Please use this identifier to cite or link to this item:
Title: Neuropeptide Downregulation in Sepsis
Authors: SILVA, Fabiano Pinheiro daMACHADO, Marcel Cerqueira CesarSALLET, Paulo ClementeZAMPIERI, Fernando GodinhoGOULART, Alessandra CarvalhoTORGGLER FILHO, FranciscoBARBEIRO, Hermes VieiraVELASCO, Irineu TadeuCRUZ NETO, Luiz Monteiro daSOUZA, Heraldo Possolo de
Citation: INFLAMMATION, v.37, n.1, p.142-145, 2014
Abstract: Neuropeptides are an extremely conserved arm of neurobiology. Despite their effects as neurohormones and neurotransmitters, a multitude of other effects have been described, putting in evidence their importance as regulators of immune responses, such as chemotaxis, oxidative burst, pro-inflammatory signaling, and many others. The effects of neuropeptides in the pathophysiology of sepsis, however, remain poorly investigated. A prospective cohort study to investigate the effects of neuropeptides in sepsis was carried out. Here, we describe that neuropeptides are downregulated during septic shock. We propose that it may be a protective mechanism of the host to avoid further inflammatory injury.
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - FM/MCM
Departamento de Clínica Médica - FM/MCM

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - HC/IPq
Instituto de Psiquiatria - HC/IPq

Artigos e Materiais de Revistas Científicas - LIM/51
LIM/51 - Laboratório de Emergências Clínicas

Files in This Item:
File Description SizeFormat 
  Restricted Access
publishedVersion (English)371.38 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.