Departamento de Patologia - FM/MPT
Collections in this community
ASO Visual Abstract: Infiltrative Tumor Borders in Colorectal Liver Metastasis: Should We Enlarge Margin Size?
ANNALS OF SURGICAL ONCOLOGY, v.28, n.SUPPL 3, suppl.3, p.446-446, 2021
Infiltrative Tumor Borders in Colorectal Liver Metastasis: Should We Enlarge Margin Size?
ANNALS OF SURGICAL ONCOLOGY, v.28, n.12, p.7636-7646, 2021
Background Surgery is the only potentially curative treatment for colorectal cancer liver metastases (CRLMs). Despite an improvement in results following resection, recurrence rates remain high. Many histopathological features have been reported as prognostic factors. Infiltrative borders are kno...
The Fibrosis-Targeted Collagen/Integrins Gene Profile Predicts Risk of Metastasis in Pulmonary Neuroendocrine Neoplasms
FRONTIERS IN ONCOLOGY, v.11, article ID 706141, 12p, 2021
Recently, collagen/integrin genes have shown promise as predictors of metastasis mainly in non-small cell lung cancer and breast cancer. However, it is unknown if these gene expression profiling differ in metastatic potential of pulmonary neuroendocrine neoplasms (PNENs). In this study, we sought...
Immunomodulatory Role of Nutrients: How Can Pulmonary Dysfunctions Improve?
FRONTIERS IN NUTRITION, v.8, article ID 674258, 21p, 2021
Nutrition is an important tool that can be used to modulate the immune response during infectious diseases. In addition, through diet, important substrates are acquired for the biosynthesis of regulatory molecules in the immune response, influencing the progression and treatment of chronic lung d...
Extracellular Matrix Proteome Remodeling in Human Glioblastoma and Medulloblastoma
JOURNAL OF PROTEOME RESEARCH, v.20, n.10, p.4693-4707, 2021
Medulloblastomas (MBs) and glioblastomas (GBMs) are high-incidence central nervous system tumors. Different origin sites and changes in the tissue microenvironment have been associated with the onset and progression. Here, we describe differences between the extracellular matrix (ECM) signatures ...
Rapid Mortality Surveillance of COVID-19 Using Verbal Autopsy
INTERNATIONAL JOURNAL OF PUBLIC HEALTH, v.66, article ID 1604249, 4p, 2021
Platelet-Based Biomarkers for Diagnosis and Prognosis in COVID-19 Patients
LIFE-BASEL, v.11, n.10, article ID 1005, 8p, 2021
Coronavirus disease 2019 (COVID-19) caused millions of deaths worldwide. COVID-19's clinical manifestations range from no symptoms to a severe acute respiratory syndrome, which can result in multiple organ failure, sepsis, and death. Severe COVID-19 patients develop pulmonary and extrapulmonary i...
New paths in pediatrics - The implementation of a Unit of Integrative Pediatrics at the Institute of Children and Adolescents, University of Sao Paulo
CLINICS, v.76, article ID e3351, 2p, 2021
Extended minimally invasive autopsy: Technical imp-rovements for the investigation of cardiopulmonary events in COVID-19
CLINICS, v.76, article ID e3543, 7p, 2021
OBJECTIVES: Ultrasound-guided minimally invasive autopsies (MIA-US) are an alternative to conventional autopsies and have been used in our institution to investigate the pathophysiology of COVID-19 since the beginning of the pandemic. Owing to the limitations of post-mortem biopsies for evaluatin...
TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors
PHARMACOLOGICAL RESEARCH, v.173, article ID 105911, 11p, 2021
In melanomas, therapy resistance can arise due to a combination of genetic, epigenetic and phenotypic mechanisms. Due to its crucial role in DNA supercoil relaxation, TOP1 is often considered an essential chemotherapeutic target in cancer. However, how TOP1 expression and activity might differ in...