Departamento de Patologia - FM/MPT

O Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP) oferece disciplinas nas áreas de Anatomia patológica, Patologia clínica e Informática médica, além de disciplinas optativas capazes de abranger a área de estudo de maneira mais ampla, promovendo o ensino e a pesquisa.


Recent Submissions

  1. ASO Visual Abstract: Infiltrative Tumor Borders in Colorectal Liver Metastasis: Should We Enlarge Margin Size?

    ANNALS OF SURGICAL ONCOLOGY, v.28, n.SUPPL 3, suppl.3, p.446-446, 2021

  2. Infiltrative Tumor Borders in Colorectal Liver Metastasis: Should We Enlarge Margin Size?

    ANNALS OF SURGICAL ONCOLOGY, v.28, n.12, p.7636-7646, 2021

    Background Surgery is the only potentially curative treatment for colorectal cancer liver metastases (CRLMs). Despite an improvement in results following resection, recurrence rates remain high. Many histopathological features have been reported as prognostic factors. Infiltrative borders are kno...

  3. The Fibrosis-Targeted Collagen/Integrins Gene Profile Predicts Risk of Metastasis in Pulmonary Neuroendocrine Neoplasms

    FRONTIERS IN ONCOLOGY, v.11, article ID 706141, 12p, 2021

    Recently, collagen/integrin genes have shown promise as predictors of metastasis mainly in non-small cell lung cancer and breast cancer. However, it is unknown if these gene expression profiling differ in metastatic potential of pulmonary neuroendocrine neoplasms (PNENs). In this study, we sought...

  4. Immunomodulatory Role of Nutrients: How Can Pulmonary Dysfunctions Improve?

    FRONTIERS IN NUTRITION, v.8, article ID 674258, 21p, 2021

    Nutrition is an important tool that can be used to modulate the immune response during infectious diseases. In addition, through diet, important substrates are acquired for the biosynthesis of regulatory molecules in the immune response, influencing the progression and treatment of chronic lung d...

  5. Extracellular Matrix Proteome Remodeling in Human Glioblastoma and Medulloblastoma

    JOURNAL OF PROTEOME RESEARCH, v.20, n.10, p.4693-4707, 2021

    Medulloblastomas (MBs) and glioblastomas (GBMs) are high-incidence central nervous system tumors. Different origin sites and changes in the tissue microenvironment have been associated with the onset and progression. Here, we describe differences between the extracellular matrix (ECM) signatures ...

  6. Rapid Mortality Surveillance of COVID-19 Using Verbal Autopsy

    INTERNATIONAL JOURNAL OF PUBLIC HEALTH, v.66, article ID 1604249, 4p, 2021

  7. Platelet-Based Biomarkers for Diagnosis and Prognosis in COVID-19 Patients

    LIFE-BASEL, v.11, n.10, article ID 1005, 8p, 2021

    Coronavirus disease 2019 (COVID-19) caused millions of deaths worldwide. COVID-19's clinical manifestations range from no symptoms to a severe acute respiratory syndrome, which can result in multiple organ failure, sepsis, and death. Severe COVID-19 patients develop pulmonary and extrapulmonary i...

  8. New paths in pediatrics - The implementation of a Unit of Integrative Pediatrics at the Institute of Children and Adolescents, University of Sao Paulo

    CLINICS, v.76, article ID e3351, 2p, 2021

  9. Extended minimally invasive autopsy: Technical imp-rovements for the investigation of cardiopulmonary events in COVID-19

    CLINICS, v.76, article ID e3543, 7p, 2021

    OBJECTIVES: Ultrasound-guided minimally invasive autopsies (MIA-US) are an alternative to conventional autopsies and have been used in our institution to investigate the pathophysiology of COVID-19 since the beginning of the pandemic. Owing to the limitations of post-mortem biopsies for evaluatin...

  10. TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors

    PHARMACOLOGICAL RESEARCH, v.173, article ID 105911, 11p, 2021

    In melanomas, therapy resistance can arise due to a combination of genetic, epigenetic and phenotypic mechanisms. Due to its crucial role in DNA supercoil relaxation, TOP1 is often considered an essential chemotherapeutic target in cancer. However, how TOP1 expression and activity might differ in...