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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorPUECH-LEAO, Pedro-
dc.contributor.authorTORRES, Inez O.-
dc.contributor.authorSILVA, Erasmo S. da-
dc.contributor.authorCESTARI, Ismar N.-
dc.contributor.authorCESTARI, Idagene A.-
dc.contributor.authorROSA, Jhenyfer M. da-
dc.contributor.authorNAHAS, William C.-
dc.contributor.authorLUCCIA, Nelson De-
dc.identifier.citationANNALS OF VASCULAR SURGERY, v.94, p.301-305, 2023-
dc.description.abstractBackground: Venous compression syndromes are clinical conditions in which the large veins are compressed by other anatomical structures. Laboratory simulations may help us better understand the hemodynamics in venous compressions by creating situations similar to those seen in vivo. The aim of this study is to produce a model of the caval bifurcation using a polymer with distensibility similar to the human vena cava. Methods: Fragments of the inferior vena cava were collected from 13 deceased kidney donors (aged 15-37 years) and were tested for deformation (strain) when subjected to distension at 50 N/cm2. Strips of 5 different polymers-thermic polyurethane and Agilus30 with Vero Magenta (AV) (in 3 different hardnesses) and silicone-were subjected to the same biomechanical tests and compared with the vena cava. A model of the caval bifurcation was produced with 3-D printing. Results: The deformation (strain) of the vena cava wall was 0.16 & PLUSMN; 0.9 when submitted to stress close to 50 N/cm2. Silicone showed a strain higher than the standard deviation of venous fragments. The strain of AV resin 95 Shore was lower than the standard deviation of the venous fragments. AV Resins 70 and 85 Shore showed strains within the standard deviation of the venous specimen, with 70 Shore being closest to the mean venous strain. Therefore, this material was selected for modeling the caval bifurcation. The computed tomography scan image generated a computer model of the caval bifurcation and was printed in 3 dimensions. In addition, the segments of 2 adjacent vertebrae were also printed to reference the compression site. Conclusions: The 3-D printing of large veins can produce models with anatomy and biome-chanics similar to those of human veins and opens a field of investigation into the hemody-namics of venous compression syndromes. Polymers with Shore A70 appear to have biomechanical properties similar to those of the vena cava wall. The model obtained in this study can be used in several in vitro studies of May-Thurner Syndrome.eng
dc.relation.ispartofAnnals of Vascular Surgery-
dc.titleThe Distensibility of the Human Vena Cava and Its Importance to In Vitro Studies of Venous Compression Syndromes: A Search for a Suitable Polymer for 3-Dimensional Printingeng
dc.rights.holderCopyright ELSEVIER SCIENCE INCeng
dc.subject.wosPeripheral Vascular Diseaseeng
dc.type.categoryoriginal articleeng
hcfmusp.publisher.cityNEW YORKeng
hcfmusp.relation.referenceGailloud P, 1997, SURG RADIOL ANAT, V19, P119eng
hcfmusp.relation.referenceKATZ AI, 1969, BIOPHYS J, V9, P1261, DOI 10.1016/S0006-3495(69)86451-9eng
hcfmusp.relation.referenceRaghavan ML, 1996, ANN BIOMED ENG, V24, P573, DOI 10.1007/BF02684226eng
hcfmusp.relation.referenceRibeiro FS, 2020, J VASC SURG-VENOUS L, V8, P1058, DOI 10.1016/j.jvsv.2020.04.005eng
hcfmusp.relation.referenceSantoshi RKN, 2018, J VASC SURG-VENOUS L, V6, P202, DOI 10.1016/j.jvsv.2017.09.007eng
hcfmusp.relation.referenceShah A, 2017, NEUROL INDIA, V65, P1350, DOI 10.4103/0028-3886.217958eng
hcfmusp.relation.referenceTomov ML, 2019, J AM HEART ASSOC, V8, DOI 10.1161/JAHA.119.014490eng
hcfmusp.relation.referencevan Vuuren TMAJ, 2018, EUR J VASC ENDOVASC, V56, P874, DOI 10.1016/j.ejvs.2018.07.022eng
hcfmusp.relation.referenceYe X, 2020, J CLIN NEUROSCI, V77, P134, DOI 10.1016/j.jocn.2020.04.123eng
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - HC/IOT
Instituto de Ortopedia e Traumatologia - HC/IOT

Artigos e Materiais de Revistas Científicas - LIM/02
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica

Artigos e Materiais de Revistas Científicas - LIM/55
LIM/55 - Laboratório de Urologia

Artigos e Materiais de Revistas Científicas - LIM/65
LIM/65 - Laboratório de Investigação Médica em Bioengenharia

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