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Title: Effects of Exercise Intensity on Cardiometabolic Parameters of Ovariectomized Obese Mice
Authors: DOS-SANTOS, AdrianoCARVALHO, Bruno do NascimentoCOSTA-SANTOS, Nicolas DaMELLO-SILVA, Fernanda Queiroz dePEREIRA, Abel de AssisJESUS, Ney Roberto deANGELIS, Katia DeIRIGOYEN, Maria ClaudiaBERNARDES, NathaliaCAPERUTO, Erico ChagasSCAPINI, Katia BilharSANCHES, Iris Callado
Citation: INTERNATIONAL JOURNAL OF SPORTS MEDICINE, v.44, n.8, p.584-591, 2023
Abstract: The aim of this study was to compare the effects of continuous-moderate vs. high-intensity interval aerobic training on cardiovascular and metabolic parameters in ovariectomized high-fat-fed mice. C57BL/6 female ovariectomized were divided into four groups (n=8): low-fat-fed sedentary (SLF); high-fat-fed sedentary (SHF); high-fat-fed moderate-intensity continuous trained (MICT-HF); and high-fat-fed high-intensity interval aerobic trained (HIIT-HF). The high-fat diet lasted 10 weeks. Ovariectomy was performed in the fourth week. The exercise training was carried out in the last four weeks of protocol. Fasting glycemia, oral glucose tolerance, arterial pressure, baroreflex sensitivity, and cardiovascular autonomic modulation were evaluated. Moderate-intensity continuous training prevented the increase in arterial pressure and promoted a reduction in HR at rest, associated with an improvement in the sympathovagal balance in MICT-HF vs. SHF. The high-intensity interval training reduced blood glucose and glucose intolerance in HIIT-HF vs. SHF and MICT-HF. In addition, it improved sympathovagal balance in HIIT-HF vs. SHF. Moderate-intensity continuous training was more effective in promoting cardiovascular benefits, while high-intensity interval training was more effective in promoting metabolic benefits.
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Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/05
LIM/05 - Laboratório de Poluição Atmosférica Experimental

Artigos e Materiais de Revistas Científicas - LIM/59
LIM/59 - Laboratório de Biologia Celular

Artigos e Materiais de Revistas Científicas - LIM/65
LIM/65 - Laboratório de Investigação Médica em Bioengenharia

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