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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | BARBOSA, Natasha D. Fairbanks | - |
dc.contributor.author | AGUIAR, Lana M. de | - |
dc.contributor.author | MARUTA, Celina W. | - |
dc.contributor.author | AOKI, Valeria | - |
dc.contributor.author | SOTTO, Miriam N. | - |
dc.contributor.author | LABINAS, Glaucia H. O. | - |
dc.contributor.author | PERIGO, Alexandre M. | - |
dc.contributor.author | SANTI, Claudia Giuli | - |
dc.date.accessioned | 2013-07-30T14:43:50Z | - |
dc.date.available | 2013-07-30T14:43:50Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, v.67, n.3, p.409-416, 2012 | - |
dc.identifier.issn | 0190-9622 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/573 | - |
dc.description.abstract | Background: Vulvo-cervico-vaginal involvement has rarely been reported in pemphigus vulgaris (PV) and has not been reported in pemphigus foliaceus (PF). Objectives: We sought to evaluate genital lesions and Papanicolaou (Pap) smears in female patients with PV and PF. Methods: This prospective study includes all consecutive cases of female patients with PV and PF seen from May 2009 to February 2010. Gynecologic examination was performed and Pap smears were collected for cytologic analysis from each patient. Results: A total of 56 patients were given a diagnosis of pemphigus (41 PV and 15 PF). Genital involvement was observed in 9 patients with PV (22%) and the vulva was the most common genital site of involvement. Of these 9 patients, 8 presented with active skin/mucous lesions. Four of 15 patients with PF had genital lesions and vulva was the exclusive site of involvement. Three of 4 patients with PF and genital involvement also showed active cutaneous lesions. Six of 56 patients (5 PV and 1 PF) presented with atypical squamous cells of undetermined significance in Pap smear analysis. Upon further pathologic review, acantholytic cells were seen, confirming the diagnosis of pemphigus. Limitations: A small number of PF cases were studied. Conclusions: Vulvar lesions were the second most frequent site of mucous membrane PV. Herein we report the first case to our knowledge of symptomatic genital lesions in a patient with PF. Moreover, acantholytic cells in Pap smears were found in a patient with PF who was in complete remission off therapy with no clinical genital lesions and no circulating anti-desmoglein-1 and anti-desmoglein-3 autoantibodies. Gynecologic evaluation in patients with pemphigus, including a careful evaluation of Pap smears, should be recommended. (J Am Acad Dermatol 2012;67:409-16.) | - |
dc.description.sponsorship | Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) | - |
dc.language.iso | eng | - |
dc.publisher | MOSBY-ELSEVIER | - |
dc.relation.ispartof | Journal of the American Academy of Dermatology | - |
dc.rights | restrictedAccess | - |
dc.subject | acantholytic cells | - |
dc.subject | atypical squamous cells of undetermined significance | - |
dc.subject | genital involvement | - |
dc.subject | Papanicolaou smears | - |
dc.subject | pemphigus foliaceus | - |
dc.subject | pemphigus vulgaris | - |
dc.subject.other | uterine cervix | - |
dc.subject.other | involvement | - |
dc.subject.other | cytology | - |
dc.title | Vulvo-cervico-vaginal manifestations and evaluation of Papanicolaou smears in pemphigus vulgaris and pemphigus foliaceus | - |
dc.type | article | - |
dc.rights.holder | Copyright MOSBY-ELSEVIER | - |
dc.identifier.doi | 10.1016/j.jaad.2011.10.004 | - |
dc.identifier.pmid | 22153790 | - |
dc.subject.wos | Dermatology | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.description.beginpage | 409 | - |
hcfmusp.description.endpage | 416 | - |
hcfmusp.description.issue | 3 | - |
hcfmusp.description.volume | 67 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | 2-s2.0-84865027466 | - |
hcfmusp.origem.id | WOS:000307824000024 | - |
hcfmusp.publisher.city | NEW YORK | - |
hcfmusp.publisher.country | USA | - |
hcfmusp.relation.reference | Ahmed AR, 2002, J EUR ACAD DERMATOL, V16, P313, DOI 10.1046/j.1468-3083.2002.00471.x | - |
hcfmusp.relation.reference | Akhyani M, 2008, BRIT J DERMATOL, V158, P478, DOI 10.1111/j.1365-2133.2007.08356.x | - |
hcfmusp.relation.reference | Amagai M, 2008, DERMATOLOGY, P417 | - |
hcfmusp.relation.reference | Batta K, 1999, BRIT J DERMATOL, V140, P945, DOI 10.1046/j.1365-2133.1999.02832.x | - |
hcfmusp.relation.reference | Bordman LA, 2008, OBSTET GYN CLIN N AM, V35, P599 | - |
hcfmusp.relation.reference | Chan E, 1998, ARCH DERMATOL, V134, P1485, DOI 10.1001/archderm.134.11.1485 | - |
hcfmusp.relation.reference | FRIEDMAN D, 1971, AM J OBSTET GYNECOL, V110, P1023 | - |
hcfmusp.relation.reference | Guedes ACM, 2002, ARCH DERMATOL, V138, P949, DOI 10.1001/archderm.138.7.949 | - |
hcfmusp.relation.reference | Gupta S, 2003, ACTA CYTOL, V47, P795, DOI 10.1159/000326609 | - |
hcfmusp.relation.reference | Lobo AZC, 2006, ACTA DERM-VENEREOL, V86, P355, DOI 10.2340/00015555-0107 | - |
hcfmusp.relation.reference | Malik M, 2005, OBSTET GYNECOL, V106, P1005, DOI 10.1097/01.AOG.0000185258.74177.91 | - |
hcfmusp.relation.reference | MIKHAIL GR, 1967, ARCH DERMATOL, V95, P496, DOI 10.1001/archderm.95.5.496 | - |
hcfmusp.relation.reference | Murrell DE, 2008, J AM ACAD DERMATOL, V58, P1043, DOI 10.1016/j.jaad.2008.01.012 | - |
hcfmusp.relation.reference | Onuma K, 2009, DIAGN CYTOPATHOL, V37, P832, DOI 10.1002/dc.21126 | - |
hcfmusp.relation.reference | Pantanowitz L, 2005, DIAGN CYTOPATHOL, V33, P401, DOI 10.1002/dc.20265 | - |
hcfmusp.relation.reference | Solomon D, 2002, JAMA-J AM MED ASSOC, V287, P2114, DOI 10.1001/jama.287.16.2114 | - |
hcfmusp.relation.reference | VALENTE PT, 1984, ACTA CYTOL, V28, P681 | - |
hcfmusp.relation.reference | Wright C, 2000, DIAGN CYTOPATHOL, V22, P304, DOI 10.1002/(SICI)1097-0339(200005)22:5<304::AID-DC9>3.0.CO;2-X | - |
hcfmusp.relation.reference | ZOSMER A, 1992, EUR J OBSTET GYN R B, V47, P260, DOI 10.1016/0028-2243(92)90163-S | - |
dc.description.index | MEDLINE | - |
hcfmusp.remissive.sponsorship | CNPq | - |
hcfmusp.lim.ref | 2012 | - |
hcfmusp.citation.scopus | 10 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MDT Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - LIM/53 Artigos e Materiais de Revistas Científicas - LIM/56 |
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art_BARBOSA_Vulvo_cervico_vaginal_manifestations_and_evaluation_of_Papanicolaou_2012.PDF | publishedVersion (English) | 1.01 MB | Adobe PDF | View/Open |
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