Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/57812
Title: Management of Older Patients with Head and Neck Cancer: A Comprehensive Review
Authors: MATOS, Leandro L.SANABRIA, AlvaroROBBINS, K. ThomasHALMOS, Gyorgy B.STROJAN, PrimozNG, Wai TongTAKES, Robert P.ANGELOS, PeterPIAZZA, CesareBREE, Remco deRONEN, OhadGUNTINAS-LICHIUS, OrlandoEISBRUCH, AvrahamZAFEREO, MarkMAKITIE, Antti A.SHAHA, Ashok R.COCA-PELAZ, AndresRINALDO, AlessandraSABA, Nabil F.COHEN, OdedLOPEZ, FernandoRODRIGO, Juan P.SILVER, Carl E.STRANDBERG, Timo E.KOWALSKI, Luiz PauloFERLITO, Alfio
Citation: ADVANCES IN THERAPY, v.40, n.5, p.1957-1974, 2023
Abstract: The projected increase in life expectancy over the next few decades is expected to result in a rise in age-related diseases, including cancer. Head and neck cancer (HNC) is a worldwide health problem with high rates of morbidity and mortality. In this report, we have critically reviewed the literature reporting the management of older patients with HNC. Older adults are more prone to complications and toxicities secondary to HNC treatment, especially those patients who are frail or have comorbidities. Thus, this population should be screened prior to treatment for such predispositions to maximize medical management of comorbidities. Chronologic age itself is not a reason for choosing less intensive treatment for older HNC patients. Whenever possible, also older patients should be treated according to the best standard of care, as nonstandard approaches may result in increased treatment failure rates and mortality. The treatment plan is best established by a multidisciplinary tumor board with shared decision-making with patients and family. Treatment modifications should be considered for those patients who have severe comorbidities, evidence of frailty (low performance status), or low performance status or those who refuse the recommendations of the tumor board.
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Artigos e Materiais de Revistas Científicas - FM/MCG
Departamento de Cirurgia - FM/MCG

Artigos e Materiais de Revistas Científicas - HC/ICESP
Instituto do Câncer do Estado de São Paulo - HC/ICESP

Artigos e Materiais de Revistas Científicas - HC/ICHC
Instituto Central - HC/ICHC

Artigos e Materiais de Revistas Científicas - LIM/28
LIM/28 - Laboratório de Cirurgia Vascular e da Cabeça e Pescoço

Artigos e Materiais de Revistas Científicas - ODS/03
ODS/03 - Saúde e bem-estar


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