• MANAGEMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME IN A CHILD WITH ADENOVIRUS PNEUMONIA: CASE REPORT AND LITERATURE REVIEW 

  OLIVEIRA, Felipe Rezende Caino de; MACIAS, Krisna de Medeiros; ROLLI, Patricia Andrea; COLLETI JUNIOR, José; CARVALHO, Werther Brunow de (Sociedade de Pediatria de São Paulo, 2020)

  ABSTRACT Objective: To report the case of a child who developed acute respiratory distress syndrome (ARDS) from a pulmonary infection by adenovirus. Case description: A female patient aged 2 years and 6 months, weighting ...
• Identifying NAHR mechanism between two distinct Alu elements through breakpoint junction mapping by NGS 

  NOVO-FILHO, Gil M.; CARVALHO, Gleyson F. S.; NASCIMENTO, Amom M.; MONTENEGRO, Marilia M.; DAMASCENO, Jullian G.; ZANARDO, Evelin A.; CHEHIMI, Samar N.; OLIVEIRA, Yanca G.; DIAS, Alexandre T.; KIM, Chong A.; KULIKOWSKI, Leslie D. (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)

  Genomic rearrangements encompass deletions, duplications, inversions, insertions and translocations and may be the cause of several genetic diseases. One of the most frequent mechanisms that generate these rearrangements ...
• Gene expression profile suggesting immunological dysregulation in two Brazilian Bloom's syndrome cases 

  MONTENEGRO, Marilia M.; QUAIO, Caio R.; PALMEIRA, Patricia; GASPARINI, Yanca; RANGEL-SANTOS, Andreia; DAMASCENO, Julian; NOVAK, Estela M.; GIMENEZ, Thamires M.; YAMAMOTO, Guilherme L.; RONJO, Rachel S.; NOVO-FILHO, Gil M.; CHEHIMI, Samar N.; ZANARDO, Evelin A.; DIAS, Alexandre T.; NASCIMENTO, Amom M.; COSTA, Thais V. M. M.; DUARTE, Alberto J. da S.; COUTINHO, Luiz L.; KIM, Chong A.; KULIKOWSKI, Leslie D. (WILEY, HOBOKEN, USA, 2020)

  Background Bloom syndrome (BS) is a rare autosomal recessive chromosome instability disorder. The main clinical manifestations are growth deficiency, telangiectasic facial erythema, immunodeficiency, and increased risk to ...
• LRBA deficiency: a new genetic cause of monogenic lupus 

  LIPHAUS, Bernadete L.; CARAMALHO, Iris; RANGEL-SANTOS, Andreia; SILVA, Clovis A.; DEMENGEOT, Jocelyne; CARNEIRO-SAMPAIO, Magda Maria Salles (BMJ PUBLISHING GROUP, LONDON, ENGLAND, 2020)
• Involvement of the central nervous system in neuroblastomas: A potential direct pathway 

  ODONE-FILHO, Vicente; CRISTOFANI, Lilian Maria; MALUF, Paulo Taufi; ALMEIDA, Maria Tereza Assis; HALLEY, Nathalia; VINCE, Carolina Sgarioni Camargo; AZAMBUJA, Alessandra Milani Prandini de; BRUMATTI, Melina; LUBRAICO, Priscilla; LOPES, Luiz Heraldo Arouche da Camara; LEITE, Katia Ramos Moreira; SILVA, Joao Luis Fernandes; PLESE, Jose Pindaro Pereira; WELTMAN, Eduardo (CHURCHILL LIVINGSTONE, EDINBURGH, SCOTLAND, 2020)

  Although frequently disseminated to other anatomical sites, neuroblastoma (NB) is rarely reported as involving the central nervous system (CNS), which may reflect insufficient research in poorly controlled systemic disease. ...
• Profile of health professionals who completed a master's, doctoral, or post-doctoral degree in one Brazilian pediatric program 

  SILVA, Clovis Artur; TRINDADE, Vitor Cavalcanti; CRUZ, Amanda Monteiro da; BLANCO, Bruna Paccola; SANTOS, Joao Fernando Vecchi; FERRARO, Alexandre Archanjo; ODONE-FILHO, Vicente; TANNURI, Uenis; CARVALHO, Werther Brunow; CARNEIRO-SAMPAIO, Magda; VIEIRA, Sandra Elisabete; GRISI, Sandra Josefina Ferraz Ellero (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2020)

  OBJECTIVE: This study aimed to determine the personal and professional characteristics, and the physical, psychiatric/psychological, and professional issues that exist among master's-, doctoral-, and post-doctoral-level ...
• Is Delirium Pediatric Confusion Assessment Method Tools Confiable? 

  OLIVEIRA, Felipe Rezende Caino de; ARAUJO, Orlei Ribeiro de; CARVALHO, Werther Brunow de (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2020)
• COVID-19 Diagnostic and Management Protocol for Pediatric Patients 

  CARLOTTI, Ana Paula de Carvalho Panzeri; CARVALHO, Werther Brunow de; JOHNSTON, Cintia; RODRIGUEZ, Isadora Souza; DELGADO, Artur Figueiredo (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2020)

  This review aims to verify the main epidemiologic, clinical, laboratory-related, and therapeutic aspects of coronavirus disease 2019 (COVID-19) in critically ill pediatric patients. An extensive review of the medical ...
• Brainstem auditory pathway of children with acute lymphoid leukemia on chemotherapy with methotrexate 

  LEITE, Renata Aparecida; VOSGRAU, Jessica Sales; CORTEZ NETO, Leticia; SANTOS, Nayara Pereira; MATAS, Sandro Luiz de Andrade; ODONE FILHO, Vicente; MATAS, Carla Gentile (ASSOC ARQUIVOS NEURO- PSIQUIATRIA, SAO PAULO SP, BRAZIL, 2020)

  Objective: Investigate the auditory pathway in the brainstem of children with acute lymphoblastic leukemia submitted to chemotherapy (by intravenous or intrathecal infusion). Methods: Fourteen children aged between 2 and ...
• Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review 

  AMARAL, Joice Anaize Tonon do; SALATINI, Renata; ARAB, Claudia; ABREU, Luiz Carlos; VALENTI, Vitor E.; MONTEIRO, Carlos B. M.; TANNURI, Uenis; TANNURI, Ana Cristina Aoun (MDPI, BASEL, SWITZERLAND, 2020)

  Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5-9.5% in the general population. Up to 40% of cirrhotic ...
• Macrophage profile and homing into breast milk in response to ongoing respiratory infections in the nursing infant 

  ZHENG, Yingying; CORREA-SILVA, Simone; SOUZA, Eloisa Correa de; RODRIGUES, Regina Maria; FONSECA, Fernanda A. Macaferri da; GILIO, Alfredo Elias; CARNEIRO-SAMPAIO, Magda; PALMEIRA, Patricia (ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, LONDON, ENGLAND, 2020)

  Studies have shown that immune components of human milk can be changed during an infection in the nursing infant. Macrophages are abundant in human milk and they are classified into inflammatory (CD16(-)) and noninflammatory ...
• The early mobilization for children in Pediatric Intensive Care 

  JOHNSTON, Cintia; CARVALHO, Werther Brunow de (ASSOC MEDICA BRASILEIRA, SAO PAULO, BRAZIL, 2020)
• A new Real Time PCR with species-specific primers from Plasmodium malariae/P. brasilianum mitochondrial cytochrome b gene 

  SANTOS, Emilly Henrique dos; YAMAMOTO, Lidia; DOMINGUES, Wilson; SANTI, Silvia Maria di; KANUNFRE, Kelly Aparecida; OKAY, Thelma Suely (ELSEVIER IRELAND LTD, CLARE, IRELAND, 2020)

  Plasmodium malariae mainly causes asymptomatic submicroscopic parasitemia in the endemic Amazon and non-endemic Atlantic Forest, where the number of cases and transmission of malaria through blood transfusion has increased. ...
• A PCR and RFLP-based molecular diagnostic algorithm for visceral leishmaniasis 

  GODOY, Natalia Souza de; LIMA-JUNIOR, Manoel Sebastiao da Costa; LINDOSO, Jose Angelo Lauletta; PEREIRA-CHIOCCOLA, Vera Lucia; OKAY, Thelma Suely; BRAZ, Lucia Maria Almeida (WOLTERS KLUWER MEDKNOW PUBLICATIONS, MUMBAI, INDIA, 2020)

  Objective: To determine an algorithm for molecular diagnosis of visceral leishmaniasis (VL) by kinetoplast DNA (kDNA) (RV1/ RV2) and internal transcriber spacer (ITS1) (LITSR/L5.8S) polymerase chain reaction (PCR), ...
• Mucopolysaccharidosis type VI: case report with first neonatal presentation with ascites fetalis and rapidly progressive cardiac manifestation 

  HONJO, Rachel Sayuri; VACA, Evelyn Cristina Nunez; LEAL, Gabriela Nunes; ABELLAN, Deipara Monteiro; IKARI, Nana Miura; JATENE, Marcelo Biscegli; MARTINS, Ana Maria; KIM, Chong Ae (BMC, LONDON, ENGLAND, 2020)

  Background The Mucopolysaccharidosis type VI (MPS VI), also known as Maroteaux-Lamy syndrome (OMIM 253200) is an autosomal recessive lysosomal disorder, caused by the deficiency of the enzyme N-acetylgalactosamine 4-sulfatase ...
• Understanding the dynamics of hydroxychloroquine blood levels in lupus nephritis 

  PEDROSA, Tatiana N.; PASOTO, Sandra G.; AIKAWA, Nadia E.; YUKI, Emily F. N.; BORBA, Eduardo F.; FERREIRA FILHO, Julio C. R.; CARRICONDO, Pedro C.; ZANETTI, Caio B.; CONDE, Paola G.; DUARTE, Nilo J. C.; FONTOURA, Nicole; ROMANO, Paschoalina; CARVALHO, Valdemir M.; SILVA, Clovis A.; BONFA, Eloisa (SAGE PUBLICATIONS LTD, LONDON, ENGLAND, 2020)

  Objectives It is unknown if hydroxychloroquine blood level dynamics impact flare rates in lupus nephritis patients. We prospectively evaluated hydroxychloroquine levels to determine which blood-based patterns are more ...
• Choledochal cysts in children: How to Diagnose and Operate on 

  TANNURI, Ana Cristina Aoun; HARA, Lucas Arjona de Andrade; PAGANOTI, Guilherme de Freitas; ANDRADE, Wagner de Castro; TANNURI, Uenis (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2020)

  OBJECTIVE: To identify the best mode for diagnosing and treating the patients with choledochal cysts. METHODS: A retrospective study was performed with medical records of patients diagnosed with choledochal cysts from ...
• Resuscitation in Extensive Burn in Pediatrics and Fluid Creep: an Update 

  DITTRICH, M.H.M.; HOSNI, N.D.; CARVALHO, W.B. de (SPRINGER, 2019)

  Purpose of review: Excessive administration of crystalloid and the abandonment of colloid replenishment at certain point of resuscitation are the major contributors to fluid overload, leading to a phenomenon termed fluid ...
• Nutritional Assessment and Body Composition in Critically Ill Children as Prognostic Indicators 

  ZAMBERLAN, P.; CARVALHO, W.B. de; DELGADO, A.F. (SPRINGER INTERNATIONAL PUBLISHING, 2019)

  Purpose of review: Malnutrition is very common in critically ill patients, mainly children and adolescents, and it increases morbidity, length of stay, medical costs, and mortality. Anthropometric and body composition ...
• Neonatal Hypotension: What Is the Efficacy of Each Anti-Hypotensive Intervention? A Systematic Review 

  MATSUSHITA, F.Y.; KREBS, V.L.J.; CARVALHO, W.B. de (SPRINGER, 2019)

  Purpose of review: There is no consensus in the treatment of hemodynamic instability in the preterm newborn. Blood pressure is one of the few measurable objective parameters for hemodynamic evaluation in this population. ...

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