Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorFIORELLI, A. I.-
dc.contributor.authorCOELHO, G. H. B.-
dc.contributor.authorAIELLO, V. D.-
dc.contributor.authorBENVENUTI, L. A.-
dc.contributor.authorPALAZZO, J. F.-
dc.contributor.authorSANTOS JUNIOR, V. P.-
dc.contributor.authorCANIZARES, B.-
dc.contributor.authorDIAS, R. R.-
dc.contributor.authorSTOLF, N. A. G.-
dc.identifier.citationTRANSPLANTATION PROCEEDINGS, v.44, n.8, p.2479-2482, 2012-
dc.description.abstractIntroduction. Tricuspid regurgitation (TR) is the most commonly valvular dysfunction found after heart transplantation (HTx). It may be related to endomyocardial biopsy (EMB) performed for allograft rejection surveillance. Objective. This investigation evaluated the presence of tricuspid valve tissue fragments obtained during routine EMB performed after HTx and its possible effect on short-term and long-term hemodynamic status. Method. This single-center review included prospectively collected and retrospectively analyzed data. From 1985 to 2010, 417 patients underwent 3550 EMB after HTx. All myocardial specimens were reviewed to identify the presence of tricuspid valve tissue by 2 observers initially and in doubtful cases by a third observer. The echocardiographic and hemodynamic parameters were only considered for valvular functional damage analysis in cases of tricuspid tissue inadvertently removed during EMB. Results. The 417 HTx patients to 3550 EMB, including 17,550 myocardial specimens. Tricuspid valve tissue was observed in 12 (2.9%) patients corresponding to 0.07% of the removed fragments. The echocardiographic and hemodynamic parameters of these patients before versus after the biopsy showed increased TR in 2 cases (2/12; 16.7%) quantified as moderate without progression in the long term. Only the right atrial pressure showed a significant increase (P = .0420) after tricuspid injury; however, the worsening of the functional class was not significant enough in any of the subjects. Thus, surgical intervention was not required. Conclusions. Histological evidence of chordal tissue in EMB specimens is a real-world problem of relatively low frequency. Traumatic tricuspid valve injury due to EMB rarely leads to severe valvular regurgitation; only a minority of patients develop significant clinical symptoms. Hemodynamic and echocardiographic alterations are also less often observed in most patients.-
dc.relation.ispartofTransplantation Proceedings-
dc.subject.othercardiac transplantation-
dc.titleTricuspid Valve Injury After Heart Transplantation Due to Endomyocardial Biopsy: An Analysis of 3550 Biopsies-
dc.rights.holderCopyright ELSEVIER SCIENCE INC-
dc.description.conferencedateOCT 01-04, 2011-
dc.description.conferencelocalBelem, BRAZIL-
dc.description.conferencenameBrazilian Transplant Congress of the Brazilian-Association-for-Organ-Transplantation / Luso-Brazilian Congress of Transplantation / Meeting of Transplant Nursing / Multidisciplinary Transplant Meeting / ABH's Histocompatibility Forum-
dc.type.categoryarticle; proceedings paper-
dc.type.versionpublishedVersion-, G. H. B.:Univ Sao Paulo, Sch Med, Inst Heart, Sao Paulo, Brazil- JUNIOR, V. P.:Univ Sao Paulo, Sch Med, Inst Heart, Sao Paulo, Brazil-, B.:Univ Sao Paulo, Sch Med, Inst Heart, Sao Paulo, Brazil-
hcfmusp.publisher.cityNEW YORK-
hcfmusp.relation.referenceAnderson CA, 2004, ANN THORAC SURG, V78, P1635, DOI 10.1016/j.athoracsur.2004.05.028-
hcfmusp.relation.referenceCAMARGO PR, 1990, INT J CARDIOL, V28, P293, DOI 10.1016/0167-5273(90)90311-R-
hcfmusp.relation.referenceChan MCY, 2001, J HEART LUNG TRANSPL, V20, P709, DOI 10.1016/S1053-2498(01)00258-3-
hcfmusp.relation.referenceFiorelli AI, 2009, TRANSPL P, V41, P935, DOI 10.1016/j.transproceed.2009.02.011-
hcfmusp.relation.referenceFiorelli AI, 2011, TRANSPL P, V43, P225, DOI 10.1016/j.transproceed.2010.12.049-
hcfmusp.relation.referenceFiorelli AI, 2007, TRANSPL P, V39, P2527, DOI 10.1016/j.transproceed.2007.07.025-
hcfmusp.relation.referenceHAUSEN B, 1995, ANN THORAC SURG, V59, P1134, DOI 10.1016/0003-4975(95)00089-4-
hcfmusp.relation.referenceIrwin RB, 2010, POSTGRAD MED J, V86, P648, DOI 10.1136/pgmj.2009.090886-
hcfmusp.relation.referenceJeevanandam V, 2006, ANN THORAC SURG, V82, P2089, DOI 10.1016/j.athoracsur.2006.07.014-
hcfmusp.relation.referenceLo Chung-Yu, 2007, J Chin Med Assoc, V70, P185-
hcfmusp.relation.referenceMENEGUETTI J C, 1987, Journal of Heart Transplantation, V6, P171-
hcfmusp.relation.referenceMielniczuk L, 2005, J HEART LUNG TRANSPL, V24, P586-
hcfmusp.relation.referenceMUGGE A, 1990, AM J CARDIOL, V66, P884, DOI 10.1016/0002-9149(90)90378-E-
hcfmusp.relation.referenceNguyen V, 2005, J HEART LUNG TRANSPL, V24, pS227, DOI 10.1016/j.healun.2004.07.007-
hcfmusp.relation.referenceRabischoffsky A, 2008, REV BRAS ECOCARDIOGR, V21, P27-
hcfmusp.relation.referenceSaraiva F, 2011, TRANSPL P, V43, P1908, DOI 10.1016/j.transproceed.2011.03.010-
hcfmusp.relation.referenceStewart S, 2005, J HEART LUNG TRANSPL, V24, P1710, DOI 10.1016/j.healun.2005.03.019-
hcfmusp.relation.referenceWARNECKE H, 1992, J HEART LUNG TRANSPL, V11, P1093-
hcfmusp.relation.referenceWong RCC, 2008, J HEART LUNG TRANSPL, V27, P247, DOI 10.1016/j.healun.2007.12.011-
Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MCP
Departamento de Cardio-Pneumologia - FM/MCP

Artigos e Materiais de Revistas Científicas - HC/ICr
Instituto da Criança - HC/ICr

Artigos e Materiais de Revistas Científicas - HC/InCor
Instituto do Coração - HC/InCor

Artigos e Materiais de Revistas Científicas - LIM/11
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação

Files in This Item:
File Description SizeFormat 
  Restricted Access
publishedVersion (English)130.34 kBAdobe PDFView/Open Request a copy

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.