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dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP-
dc.contributor.authorCORREIA-DEUR, Joya Emilie de M.-
dc.contributor.authorCLAUDIO, Luz-
dc.contributor.authorIMAZAWA, Alice Takimoto-
dc.contributor.authorELUF-NETO, Jose-
dc.identifier.citationAMERICAN JOURNAL OF INDUSTRIAL MEDICINE, v.55, n.12, Special Issue, p.1087-1098, 2012-
dc.description.abstractBackground In the last 20 years, there has been an increase in the incidence of allergic respiratory diseases worldwide and exposure to air pollution has been discussed as one of the factors associated with this increase. The objective of this study was to investigate the effects of air pollution on peak expiratory flow (PEF) and FEV1 in children with and without allergic sensitization. Methods Ninety-six children were followed from April to July, 2004 with spirometry measurements. They were tested for allergic sensitization (IgE, skin prick test, eosinophilia) and asked about allergic symptoms. Air pollution, temperature, and relative humidity data were available. Results Decrements in PEF were observed with previous 24-hr average exposure to air pollution, as well as with 310-day average exposure and were associated mainly with PM10, NO2, and O3 in all three categories of allergic sensitization. Even though allergic sensitized children tended to present larger decrements in the PEF measurements they were not statistically different from the non-allergic sensitized. Decrements in FEV1 were observed mainly with previous 24-hr average exposure and 3-day moving average. Conclusions Decrements in PEF associated with air pollution were observed in children independent from their allergic sensitization status. Their daily exposure to air pollution can be responsible for a chronic inflammatory process that might impair their lung growth and later their lung function in adulthood. Am. J. Ind. Med. 55:10871098, 2012. (c) 2012 Wiley Periodicals, Inc.-
dc.description.sponsorshipMount Sinai School of Medicine ITREOH Program-
dc.description.sponsorshipFogarty International Center of the National Institutes of Health (NIH-FIRCA) [1D43 TW000640]-
dc.description.sponsorshipFogarty International Center, National Institute of Environmental Health Sciences (NIH-NIEHS)-
dc.description.sponsorshipNational Institutes of Health (NIH)-
dc.description.sponsorshipFogarty International Center (NIH-FIRCA) [D43TW000640]-
dc.description.sponsorshipNational Institute of Environmental Health Sciences (NIH-NIEHS)[D43ES018745]-
dc.relation.ispartofAmerican Journal of Industrial Medicine-
dc.subjectair pollution-
dc.subjectadverse effects-
dc.subjectpeak expiratory flow-
dc.subjectallergic sensitization-
dc.subjectlinear models-
dc.subject.otherenvironmental tobacco-smoke-
dc.subject.otherinner-city children-
dc.subject.otherrespiratory symptoms-
dc.subject.otherozone exposure-
dc.subject.otherpm10 pollution-
dc.subject.otherambient ozone-
dc.titleVariations in peak expiratory flow measurements associated to air pollution and allergic sensitization in children in Sao Paulo, Brazil-
dc.rights.holderCopyright WILEY-BLACKWELL-
dc.subject.wosPublic, Environmental & Occupational Health-
dc.type.categoryoriginal article-
dc.type.versionpublishedVersion-, Luz:Mt Sinai Sch Med, Dept Prevent Med, New York, NY USA-, Alice Takimoto:Univ Sao Paulo, Dept Endocrinol & Metabol, Fac Med, BR-01246903 Sao Paulo, Brazil-
hcfmusp.description.issueSpecial Issue-
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Appears in Collections:

Artigos e Materiais de Revistas Científicas - FM/MPR
Departamento de Medicina Preventiva - FM/MPR

Artigos e Materiais de Revistas Científicas - LIM/25
LIM/25 - Laboratório de Endocrinologia Celular e Molecular

Artigos e Materiais de Revistas Científicas - LIM/38
LIM/38 - Laboratório de Epidemiologia e Imunobiologia

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