Please use this identifier to cite or link to this item: https://observatorio.fm.usp.br/handle/OPI/957
Title: Cholesterol-lowering effect of whole lupin (Lupinus albus) seed and its protein isolate
Authors: FONTANARI, Gustavo GuadagnucciBATISTUTI, Jose PaschoalCRUZ, Robison Jose daSALDIVA, Paulo Hilario NascimentoAREAS, Jose Alfredo Gomes
Citation: FOOD CHEMISTRY, v.132, n.3, p.1521-1526, 2012
Abstract: This study describes the hypocholesterolaemic effect of whole lupin and its protein in hamsters. The diets were: casein (control group HC), lupin protein isolate (group HPI) and whole lupin seed (group HWS). Diets from HPI and HWS promoted a significant reduction of total cholesterol and non-HDL cholesterol in the hamsters' plasma as compared with HC. The true digestibility of HPI and HC groups were similar and differed significantly from the HWS one, which in turn showed a significant difference in total sterol excretion as compared to the former groups. Histological analysis of the liver revealed that animals fed on HPI and HWS diets presented a low level of steatosis (level 1) as compared to the ones fed on HC diet (level 4). Our findings demonstrate that protein isolate from Lupinus albus from Brazil has a metabolic effect on endogenous cholesterol metabolism and a protector effect on development of hepatic steatosis.
Appears in Collections:Artigos e Materiais de Revistas Científicas - FM/MPT
Artigos e Materiais de Revistas Científicas - FM/Outros
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - HC/InCor
Artigos e Materiais de Revistas Científicas - LIM/05

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