Instituto de Psiquiatria - HC/IPq
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The thalamus and its subnuclei-a gateway to obsessive-compulsive disorder
TRANSLATIONAL PSYCHIATRY, v.12, n.1, article ID 70, 10p, 2022
Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population. Particular thalamic subregions may drive these differences. The ENIGMA-OCD working group conducted mega- and meta-analyses to study t...
Counseling about sudden unexpected death in epilepsy (SUDEP): A global survey of neurologists' opinions
EPILEPSY & BEHAVIOR, v.128, article ID 108570, 7p, 2022
Objective: To investigate the opinions and attitudes of neurologists on the counseling about sudden unex-pected death in epilepsy (SUDEP) worldwide. Methods: Practicing neurologists from around the world were invited to participate in an online survey. On February 18th, 2021, we emailed an invita...
Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 2. Screening, intervention, and prevention
BRAZILIAN JOURNAL OF PSYCHIATRY, v.43, n.5, p.538-549, 2021
This article continues our presentation of the Brazilian Psychiatric Association guidelines for the management of patients with suicidal behavior, with a focus on screening, intervention, postvention, prevention, and promotion. For the development of these guidelines, we conducted a systematic re...
Ketamine in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
HARVARD REVIEW OF PSYCHIATRY, v.30, n.2, p.135-145, 2022
Introduction First-line treatment for obsessive-compulsive disorder (OCD) includes exposure and response prevention behavioral therapy and serotonin reuptake inhibitors, particularly in combination. New and more effective treatments are needed, give that recent studies suggest that glutamatergic ...
Barriers to treatment for mental disorders in six countries of the Americas: A regional report from the World Mental Health Surveys
JOURNAL OF AFFECTIVE DISORDERS, v.303, p.273-285, 2022
ABS T R A C T Background: Mental health treatment is scarce and little resources are invested in reducing the wide treatment gap that exists in the Americas. The regional barriers are unknown. We describe the barriers for not seeking treatment among those with mental and substance use disorders f...
Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 1. Risk factors, protective factors, and assessment
BRAZILIAN JOURNAL OF PSYCHIATRY, v.43, n.5, p.525-537, 2021
Suicide is a global public health problem that causes the loss of more than 800,000 lives each year, principally among young people. In Brazil, the average mortality rate attributable to suicide is approximately 5.23 per 100,000 population. Although many guidelines have been published for the man...
I don't need any treatment'' - barriers to mental health treatment in the general population of a megacity
BRAZILIAN JOURNAL OF PSYCHIATRY, v.43, n.6, p.590-598, 2021
Objective: Most countries fail to treat individuals with psychopathologies. Investigating treatment barriers and reasons for dropout are key elements to overcoming this scenario. Methods: A representative sample of 2,942 urban-dwelling adults was interviewed face-to-face within a cross-sectional,...
The Family Health Strategy as an indicator for coping with COVID-19 in Santa Catarina, Brazil
ARCHIVOS DE MEDICINA, v.21, n.1, p.238-246, 2021
Objective: to relate the coverage by the FHS and the availability of respirators with the transmission and mortality rate of COVID-19 in the state of Santa Catarina, Brazil. Materials and methods: this is an ecological study, which uses computational models of geospatial analysis on the progress ...
Global mortality from dementia: Application of a new method and results from the Global Burden of Disease Study 2019
ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS, v.7, n.1, article ID e12200, 28p, 2021
Introduction Dementia is currently one of the leading causes of mortality globally, and mortality due to dementia will likely increase in the future along with corresponding increases in population growth and population aging. However, large inconsistencies in coding practices in vital registrati...
Different routes of administration in chronic migraine prevention lead to different placebo responses: a meta-analysis
PAIN, v.163, n.3, p.415-424, 2022
Placebo response is a powerful determinant of health outcomes in several disorders. Meta-analysis of clinical trials in pain conditions shows that it can contribute up to 75% of the overall treatment effect. Placebo response deriving from different routes of administration is poorly understood in...