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DC Field | Value | Language |
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dc.contributor | Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP | - |
dc.contributor.author | MOURA JUNIOR, Nabor Bezerra de | - |
dc.contributor.author | DAS-NEVES-PEREIRA, Joao Carlos | - |
dc.contributor.author | CAMPOS, Jose Ribas Milanez de | - |
dc.contributor.author | OLIVEIRA, Flavio Roberto Garbelini de | - |
dc.contributor.author | WOLOSKER, Nelson | - |
dc.contributor.author | PARRA, Edwin Roger | - |
dc.contributor.author | CAPELOZZI, Vera Luiza | - |
dc.contributor.author | JATENE, Fabio Biscegli | - |
dc.date.accessioned | 2013-07-30T15:14:59Z | - |
dc.date.available | 2013-07-30T15:14:59Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | MOLECULAR NEUROBIOLOGY, v.45, n.2, p.362-365, 2012 | - |
dc.identifier.issn | 0893-7648 | - |
dc.identifier.uri | https://observatorio.fm.usp.br/handle/OPI/970 | - |
dc.description.abstract | The goal of this study was to evaluate if the immunohistochemical expression of alpha-3 neuronal nicotinic acetylcholine receptor subunit in sympathetic ganglia remains stable after brain death, determining the possible use of sympathetic thoracic ganglia from subjects after brain death as study group. The third left sympathetic ganglion was resected from patients divided in two groups: BD-organ donors after brain death and CON-patients submitted to sympathectomy for hyperhidrosis (control group). Immunohistochemical staining for alpha-3 neuronal nicotinic acetylcholine receptor subunit was performed; strong and weak expression areas were quantified in both groups. The BD group showed strong alpha-3 neuronal nicotinic acetylcholine receptor expression in 6.55% of the total area, whereas the CON group showed strong expression in 5.91% (p = 0.78). Weak expression was found in 6.47% of brain-dead subjects and in 7.23% of control subjects (p = 0.31). Brain death did not affect the results of the immunohistochemical analysis of sympathetic ganglia, and its use as study group is feasible. | - |
dc.language.iso | eng | - |
dc.publisher | HUMANA PRESS INC | - |
dc.relation.ispartof | Molecular Neurobiology | - |
dc.rights | restrictedAccess | - |
dc.subject | Brain death | - |
dc.subject | Ganglia | - |
dc.subject | sympathetic | - |
dc.subject | Receptors | - |
dc.subject | nicotinic | - |
dc.subject | Nicotinic receptor subunit alpha3 | - |
dc.subject | Immunohistochemistry | - |
dc.subject | Human | - |
dc.subject.other | palmar hyperhidrosis | - |
dc.subject.other | skin-response | - |
dc.subject.other | mechanisms | - |
dc.title | Preservation of Alpha-3 Neuronal Nicotinic Acetylcholine Receptor Expression in Sympathetic Ganglia After Brain Death | - |
dc.type | article | - |
dc.rights.holder | Copyright HUMANA PRESS INC | - |
dc.identifier.doi | 10.1007/s12035-012-8235-3 | - |
dc.identifier.pmid | 22274960 | - |
dc.subject.wos | Neurosciences | - |
dc.type.category | original article | - |
dc.type.version | publishedVersion | - |
hcfmusp.description.beginpage | 362 | - |
hcfmusp.description.endpage | 365 | - |
hcfmusp.description.issue | 2 | - |
hcfmusp.description.volume | 45 | - |
hcfmusp.origem | WOS | - |
hcfmusp.origem.id | WOS:000302099200012 | - |
hcfmusp.origem.id | 2-s2.0-84862693774 | - |
hcfmusp.publisher.city | TOTOWA | - |
hcfmusp.publisher.country | USA | - |
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dc.description.index | MEDLINE | - |
hcfmusp.lim.ref | 2012 | - |
hcfmusp.citation.scopus | 3 | - |
hcfmusp.scopus.lastupdate | 2024-04-12 | - |
Appears in Collections: | Artigos e Materiais de Revistas Científicas - FM/MCG Artigos e Materiais de Revistas Científicas - FM/MCP Artigos e Materiais de Revistas Científicas - FM/MPT Artigos e Materiais de Revistas Científicas - HC/ICHC Artigos e Materiais de Revistas Científicas - HC/InCor Artigos e Materiais de Revistas Científicas - LIM/28 Artigos e Materiais de Revistas Científicas - LIM/61 |
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