Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPRUDAKOFF, Livia Carolina SobrinhoMAGALHAES, Elma Izze da SilvaVIOLA, Poliana Cristina de Almeida FonsecaOLIVEIRA, Bianca Rodrigues deCOELHO, Carla Cristine Nascimento da SilvaBRAGANCA, Maylla Luanna Barbosa MartinsARRUDA, Soraia Pinheiro MachadoCARDOSO, Viviane CunhaBETTIOL, HeloisaBARBIERI, Marco AntonioLEVY, Renata BertazziSILVA, Antonio Augusto Moura da2023-02-232023-02-232022FRONTIERS IN NUTRITION, v.9, article ID 1006018, 12p, 20222296-861Xhttps://observatorio.fm.usp.br/handle/OPI/51649ObjectiveTo investigate the association between ultra-processed food consumption at 23-25 years of age and measurements of body composition-fat mass, fat mass distribution and lean mass at 37-39 years of age in Brazilian adults. Methods1978/1979 birth cohort study conducted with healthy adults from Ribeirao Preto, Sao Paulo, Brazil. A total of 1,021 individuals participated in the fat mass analysis (measured by air displacement plethysmography) and 815 in the lean mass analysis and fat mass distribution (assessed by dual energy X-ray absorptiometry). Food consumption was evaluated by a food frequency questionnaire. Food items were grouped according to the level of processing as per the NOVA classification. Ultra-processed food consumption was expressed as a percentage of total daily intake (g/day). Linear regression models were used to estimate the effect of ultra-processed food consumption (g/day) on body mass index, body fat percentage, fat mass index, android fat, gynoid fat, android-gynoid fat ratio, lean mass percentage, lean mass index and appendicular lean mass index. Marginal plots were produced to visualize interactions. ResultsThe mean daily ultra-processed food consumption in grams was 35.8% (813.3 g). There was an association between ultra-processed food consumption and increase in body mass index, body fat percentage, fat mass index, android fat and gynoid fat and decrease in lean mass percentage, only in women. ConclusionA high ultra-processed food consumption is associated with a long-term increase in fat mass and a decrease in lean mass in adult women.engopenAccessultra-processed foods (UPFs)food consumptiondietbody compositionbody fatribeirao-pretometaanalysissarcopeniaproteinweightadultshealthimpactarticleCopyright FRONTIERS MEDIA SA10.3389/fnut.2022.1006018Nutrition & Dietetics