Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPGENTA-PEREIRA, Daniel CastanhoPEDROSA, Rodrigo P.LORENZI-FILHO, GeraldoDRAGER, Luciano F.2015-02-062015-02-062014CURRENT HYPERTENSION REPORTS, v.16, n.8, article ID 459, 7p, 20141522-6417https://observatorio.fm.usp.br/handle/OPI/8305Two main sleep disturbances, namely obstructive sleep apnea (OSA) and sleep deprivation, have gained growing interest in the field of hypertension research. This fact is supported not only by evidence that both disturbances are quite common in modern societies but also that OSA and sleep deprivation are associated with several pathways that may contribute to a predisposition to hypertension or even exacerbate blood pressure levels in hypertensive patients. In the present review, we will discuss current evidence supporting a potential role of these sleep disturbances in the resistant hypertension scenario.engrestrictedAccessCardiovascular riskHypertensionSleep apneaSleep deprivationSleep disturbancespositive airway pressurerenin-angiotensin systemrostral fluid shiftblood-pressurearterial stiffnesshealthy-subjectsincreased endothelin-1berlin questionnaireintermittent hypoxiaapnea syndromearticleCopyright SPRINGER10.1007/s11906-014-0459-3Peripheral Vascular Disease1534-3111