Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPBITTENCOURT, Aline GomesTSUJI, Robinson KojiCABRAL JUNIOR, FranciscoPEREIRA, Larissa VilelaFONSECA, Anna Carolina de OliveiraALVES, VenâncioBENTO, Ricardo Ferreira2014-07-042014-07-042013INTERNATIONAL ARCHIVES OF OTORHINOLARYNGOLOGY, v.17, n.3, p.340-343, 20131809-4864https://observatorio.fm.usp.br/handle/OPI/5867INTRODUCTION: Adenomas with neuroendocrine differentiation are defined as neuroendocrine neoplasms, and they are rarely found in the head and neck. OBJECTIVE: To describe two cases of a middle ear adenoma with neuroendocrine differentiation, with a literature review. CASE REPORT: Patient 1 was a 41-year-old woman who presented with a 3-year history of left aural fullness associated with ipsilateral ""hammer beating"" tinnitus. Patient 2 was a 41-year-old male who presented with unilateral conductive hearing loss. CONCLUSION: Adenoma with neuroendocrine differentiation of the middle ear is a rare entity, but it should be considered in patients with tinnitus, aural fullness, and a retrotympanic mass and remembered as a diferential diagnosis of tympanic paraganglioma.engopenAccessNeuroendocrine TumorsHearing LossAdenomaarticleCopyright Fundação Otorrinolaringologia10.7162/S1809-977720130003000015Otorhinolaryngology