Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPFARIAS, Luis Arthur Brasil GadelhaHOLANDA, Pablo Eliack Linhares deSILVA, Ana Danielle Tavares daCAVALCANTE, Karene FerreiraJUCA, Marina Catunda PinheiroNETO, Lauro Vieira PerdigaoDAMASCENO, Lisandra Serra2024-04-052024-04-052023REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, v.56, article ID e02282023, 4p, 20230037-8682https://observatorio.fm.usp.br/handle/OPI/59106Herein, we report two cases of severe mpox in patients with advanced acquired immunodeficiency syndrome from Brazil who developed atypical lesions and prolonged illness, one of whom had a fatal outcome. Both patients experienced serious complications involving the perianal and genital regions and prolonged disease with persistent viremia.engopenAccessMpoxHIVImmunosuppressionarticleCopyright SOC BRASILEIRA MEDICINA TROPICAL10.1590/0037-8682-0228-2023ParasitologyTropical Medicine