Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPTEIXEIRA, SilmarMACHADO, SergioVELASQUES, BrunaSANFIM, AntonioMINC, DanielPERESSUTTI, CarolineBITTENCOURT, JulianaBUDDE, HenningCAGY, MauricioANGHINAH, RenatoBASILE, Luis F.PIEDADE, RobertoRIBEIRO, PedroDINIZ, ClaudiaCARTIER, ConsueloGONGORA, MarianaSILVA, FarmyMANAIA, FemandaSILVA, Julio Guilherme2014-09-302014-09-302014JOURNAL OF THE NEUROLOGICAL SCIENCES, v.338, n.1-2, p.12-22, 20140022-510Xhttps://observatorio.fm.usp.br/handle/OPI/7783For many decades the parietal cortex (PC) has been considered the key area in tasks which involve the integration of different stimuli. PC is fundamental to determine spatial sense, information navigation and integration, and is involved in several aspects of the complex motor repertoire and in neurological and psychiatric disorders. In this review, we focus on seven different aspects of PC: (i) neuroanatomy of the parietal cortex; (ii) sensory motor integration processes; iii) hand movement control: reaching, grasping, and pointing; (iv) saccadic eye movements; (v) movement observation; (vi) neurological aspects: ataxia, autism and Parkinson's disease; and (vii) psychiatric aspects: schizophrenia, bipolar disorder and depression. Among these, we related the perspectives which involve the functions of the parietal cortex and mirror neurons and that seem to play a fundamental role in action prediction, planning, observation and execution. Furthermore, we focused on the relationship between posterior parietal cortex (PPC) and hand-guided movements. For this review, we conducted an academic paper search which fulfilled the objective of the study. We conclude that the PC has great participation in different motor functions and neurological/psychiatric disorders.engrestrictedAccessParietal cortexSensorimotor integrationHand movement controlNeurological and psychiatric aspectsNeuroanatomyMovement observationsaccadic eye-movementstranscranial magnetic stimulationparkinsons-diseasesomatosensory cortexoptic ataxiabipolar disordervisual-attentionmacaque monkeydifferential activationparietooccipital cortexarticleCopyright ELSEVIER SCIENCE BV10.1016/j.jns.2013.12.025Clinical NeurologyNeurosciences1878-5883