Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPOLIART-GUZMAN, HumbertoDELFINO, Breno M.MARTINS, Antonio C.MANTOVANI, Saulo A. S.BRANA, Athos M.PEREIRA, Thasciany M.BRANCO, Fernando L. C. C.RAMALHO, Alanderson A.CAMPOS, Rhanderson G.FONTOURA, Pablo S.ARAUJO, Thiago S. deOLIVEIRA, Cristieli S. M. deMUNIZ, Pascoal T.RUBINSKY-ELEFANT, GuitaCODECO, Claudia T.SILVA-NUNES, Monica da2014-09-302014-09-302014AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, v.90, n.4, p.670-681, 20140002-9637https://observatorio.fm.usp.br/handle/OPI/7954Toxocara spp. infection and the seroconversion rate in the Amazon have been poorly investigated. This study analyzed individual and household-level risk factors for the presence of IgG antibodies to Toxocara spp. in urban Amazonian children over a period of 7 years and evaluated the seroconversion rates over a 1-year follow-up. In children < 59 months of age, the overall prevalence rate was 28.08% in 2003 and 23.35% in 2010. The 2010-2011 seroconversion rates were 13.90% for children 6-59 months of age and 12.30% for children 84-143 months of age. Multilevel logistic regression analysis identified child age, previous wheezing, and current infection with hookworm as significant associated factors for Toxocara spp. seropositivity in 2003. In 2010, age, previous helminthiasis, and having a dog were associated with seropositivity, whereas having piped water inside the household was a protective factor. Control programs mainly need to target at-risk children, water quality control, and animal deworming strategies.engopenAccesslinked-immunosorbent-assayvisceral larva migranssao-paulo staterisk-factorsspatial-distributioncanis infectionschool-childrenseroepidemiological surveyclinical expressionacre statearticleCopyright AMER SOC TROP MED & HYGIENE10.4269/ajtmh.13-0506Public, Environmental & Occupational HealthTropical Medicine1476-1645