Correlation between retinal sensitivity assessed by microperimetry and structural abnormalities on optical coherence tomography after successful epiretinal membrane surgery

Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPMATOS, Aline Mota FreitasDEFINA, Raphael Lucas SampaioCOSTA-CUNHA, Luciana Virginia FerreiraZACHARIAS, Leandro CabralPRETI, Rony CarlosMONTEIRO, Mario Luiz RibeiroCUNHA, Leonardo Provetti2024-04-052024-04-052024INTERNATIONAL JOURNAL OF RETINA AND VITREOUS, v.10, n.1, article ID 24, 11p, 2024https://observatorio.fm.usp.br/handle/OPI/58930BackgroundTo verify the correlation between retinal sensitivity (RS) assessed by the microperimetry (MP) and optical coherence tomography (OCT) parameters measured in eyes submitted to pars-plana vitrectomy (PPV) for idiopathic epiretinal membrane (ERM) treatment.Methods43 patients underwent PPV. Best-corrected visual acuity (BCVA) and OCT imaging were acquired preoperatively and 6 months after surgery. The RS values were recorded 6 months after the surgery. Total macular thickness (TMT) measurements and OCT-evaluated structural findings were also analyzed. The MP examination tested 44 points, with direct topographic correspondence with the OCT-ETDRS map. Correlations between BCVA, RS, and OCT parameters were assessed.ResultsTMT measurements in patients were significantly thicker preoperatively and reduced after surgery. All patients demonstrated BCVA improvements after surgery. The RS parameters after surgery were significantly lower in patients. For OCT structural analyses, patients with lower RS at the fovea correlated with the preexisting disorganization of retinal inner layers (DRIL). In addition, lower RS values were associated with DRIL, outer retinal changes (ORC), and intraretinal microcysts after surgery.ConclusionsThe RS values after surgery were significantly lower when compared to controls. The DRIL presence before and after surgery, and microcysts and ORC after surgery were related to worse visual outcomes.engopenAccessDisorganization of the retinal inner layers/DRILDissociated optic nerve fiber layer/DONFLEpiretinal membraneMaculaMicrocystsMicroperimeter/microperimetryOptical coherence tomographyOuter retinal changesPars-plana posterior vitrectomyRetinainternal limiting membranevisual-acuityremovallayersedemaCorrelation between retinal sensitivity assessed by microperimetry and structural abnormalities on optical coherence tomography after successful epiretinal membrane surgeryarticleCopyright BMC10.1186/s40942-024-00542-8Ophthalmology2056-9920