Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPNETO, Taurino dos Santos RodriguesNETO, Epitacio Dias da SilvaHIGASHI, Alex HaruoMEGNIS, Bianca PartezaniHADDAD, Maria Aparecida OnukiMONTEIRO, Mario Luiz RibeiroZACHARIAS, Leandro Cabral2024-04-052024-04-052024ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, v.87, n.5, article ID e20210472, 7p, 20240004-2749https://observatorio.fm.usp.br/handle/OPI/58926Purpose: Microperimetry has been used for several years as a form of visual function testing in patients with retinal diseases. Normal microperimetry values obtained with microperimeter MP-3 have not yet been fully published, and baseline values for topographic macular sensitivity and correlations with age and sex are needed to establish degrees of impairment. This study aimed to determine values for light sensitivity thresholds and fixation stability using the MP-3 in healthy individuals. Methods: Thirty-seven healthy volunteers (age, 28-68 years), underwent full-threshold microperimetry using a 4-2 (fast) staircase strategy with the standard Goldmann III stimulus size and 68 test points positioned identically to those in the Humphrey Field Analyzer 10-2 test grid. The fixation stability was simultaneously recorded during the microperimetry test. The relationship between global sensitivity and age was calculated using linear regression analysis. Results: Microperimetry was performed on 37 participants (74 eyes). The global mean sensitivity was 29.01 +/- 1.44 (range, 26-31) dB. The mean central sensitivity at 2 degrees measured by the MP-3 was 28.5 +/- 1.77 dB in the right eye (OD) and 28.75 +/- 1.98 dB in the left eye (OS). The total median fixation stability values within 2 degrees and 4 degrees were 80% and 96%, respectively. The linear regression analysis also revealed an age-related global sensitivity decline per year of -0.051 dB +/- 0.018 (OD) and -0.078 dB +/- 0.021 (OS). Conclusions: Microperimetry performed with the MP-3 allows for an automatic, accurate, and topography-specific examination of retinal sensitivity thresholds. The results of this study provide a normal and age-matched database of MP-3 microperimetry.engopenAccessVisual fieldsVisual field testsRetinaMicroperi- metryAgesensitivityarticleCopyright CONSEL BRASIL OFTALMOLOGIA10.5935/0004-2749.2021-0472Ophthalmology1678-2925