Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPPEREIRA, Graziella HannaGARCIA, Doroti O.MOSTARDEIRO, MarceloFANTI, Karina S. V. N.LEVIN, Anna S.2013-09-232013-09-232013MEMORIAS DO INSTITUTO OSWALDO CRUZ, v.108, n.1, p.113-115, 20130074-0276https://observatorio.fm.usp.br/handle/OPI/1972This study describes a carbapenem-resistant Klebsiella pneumoniae (CRKP) outbreak that occurred from October 2008-December 2010. Polymerase chain reaction assays were performed to detect the bla(KPC) gene and molecular typing was performed using pulsed-field gel electrophoresis (PFGE). There were 33 CRKP infections; PFGE revealed five genotypes: genotype A in five (15%), B in 18 (55%), C in eight (24%) and two unique profiles. Genotype B was disseminated in all hospital units and belonged to the same clone identified in 11 different hospitals in the state of Sao Paulo. Sixteen (48%) patients died. Seven isolates (21%) were resistant to polymyxin B and 45% were resistant to tigecycline and amikacin.engopenAccesscarbapenem-resistant K. pneumoniaenosocomial outbreakpolymyxin resistancefield gel-electrophoresisbeta-lactamasebrazilinfectionarticleCopyright FUNDACO OSWALDO CRUZ10.1590/S0074-02762013000100019ParasitologyTropical Medicine