Sleep quality is a predictor of muscle mass, strength, quality of life, anxiety and depression in older adults with obesity

Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPGENARIO, RafaelGIL, SauloOLIVEIRA-JUNIOR, GersielLEITAO, Alice ErwigFRANCO, TathianeSALES, Ruan Celio dos SantosFERRIOLLI, EduardoBUSSE, Alexandre LeopoldJACOB FILHO, WilsonGUALANO, BrunoROSCHEL, Hamilton2023-10-302023-10-302023SCIENTIFIC REPORTS, v.13, n.1, article ID 11256, 9p, 20232045-2322https://observatorio.fm.usp.br/handle/OPI/55977We aimed to investigate associations between sleep quality with selected quantitative and qualitative parameters of health in older individuals with obesity. Cross-sectional assessment (n = 95 men/women; & GE; 65 years; BMI & GE; 30 kg/m(2)) of sleep quality, body composition, handgrip strength, quality-of-life, anxiety/depression. Mean PSQI score was 6.3. Poor sleepers (n = 49) presented lower appendicular lean mass (ALM) (16.2 vs 17.8 kg; p = 0.0273), ALM/BMI (0.47 vs 0.53 kg/BMI; p = 0.0085), fat mass (48.6 vs 46.6%; p = 0.0464), handgrip strength (19.7 vs 22.0 kgf; p = 0.0542) and handgrip/BMI (0.57 vs 0.66 kgf/BMI; p = 0.0242) than good sleepers. They also had higher anxiety (8.6 vs 5.6; p = 0.0100) and depression (4.8 vs 3.2; p = 0.0197) scores, worse health-related quality-of-life and lower scores in mental (62.8 vs 73.0; p = 0.0223) and physical (52.9 vs 67.3; p = 0.0015) domains. Adjusted models showed that PSQI was negatively associated with ALM (& beta; = - 0.13, 95% CI - 0.25; - 0.01) and health-related quality of life on physical (& beta; = - 2.76, 95% CI - 3.82; - 1.70) and mental (& beta; = - 2.25, 95% CI - 3.38; - 1.12) domains, and positively associated with anxiety (& beta; = 0.57; 95% CI 0.26; 0.87) and depression (& beta; = 0.31; 95% CI 0.13; 0.49). Poor sleep quality associates with impaired selected quantitative and qualitative parameters of health. Additionally, sleep quality was shown as an independent predictor of ALM, health-related quality-of-life, anxiety and depression in older individuals with obesity.engopenAccesspoor sleeppsychiatric-disordersphysical performanceassociationvalidationdeclinehealthSleep quality is a predictor of muscle mass, strength, quality of life, anxiety and depression in older adults with obesityarticleCopyright NATURE PORTFOLIO10.1038/s41598-023-37921-4Multidisciplinary Sciences