Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPCASTRO-LIMA, Victor A. C.SANTOS, Ana Paula T.MUSQUEIRA, Priscila T.MALUF, Natalya Z.RAMOS, Jessica F.MARIANO, LiviaROCHA, VandersonCOSTA, Silvia F.2023-08-162023-08-162023EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, v.42, n.7, p.899-902, 20230934-9723https://observatorio.fm.usp.br/handle/OPI/54574The aim of this study was to evaluate the prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation candidates, using tuberculin skin test and QuantiFERON-TB Gold-Plus, in a high-burden tuberculosis country. Adult candidates for hematopoietic stem cell transplantation performed both tests before and those submitted to transplantation were followed up for 12 months. The prevalence of latent Mycobacterium tuberculosis infection was 17.1% and a moderate agreement between QuantiFERON-TB Gold-Plus and tuberculin skin test was observed in this population. Previous tuberculosis exposure was a risk factor for latent Mycobacterium tuberculosis infection. No cases of tuberculosis were diagnosed during follow-up period.engrestrictedAccessHematopoietic stem cell transplantationImmunocompromised hostInterferon-gamma release testsTuberculosisTuberculinrecipientsarticleCopyright SPRINGER10.1007/s10096-023-04613-wInfectious DiseasesMicrobiology1435-4373