Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPRODRIGUES, BrunoLIRA, Fabio S.CONSOLIM-COLOMBO, Fernanda M.ROCHA, Juraci A.CAPERUTO, Erico C.ANGELIS, Katia DeIRIGOYEN, Maria-Claudia2014-09-302014-09-302014MEDIATORS OF INFLAMMATION, 20140962-9351https://observatorio.fm.usp.br/handle/OPI/7819The cardiovascular autonomic imbalance in patients after myocardial infarction (MI) provides a significant increase in mortality rate, and seems to precede metabolic, hormonal, and immunological changes. Moreover, the reduction in the parasympathetic function has been associated with inflammatory response in different pathological conditions. Over the years, most of the studies have indicated the exercise training (ET) as an important nonpharmacological tool in the management of autonomic dysfunction and reduction in inflammatory profile after a myocardial infarction. In this work, we reviewed the effects of ET on autonomic imbalance after MI, and its consequences, particularly, in the post-MI inflammatory profile. Clinical and experimental evidence regarding relationship between alterations in autonomic regulation and local or systemic inflammation response after MI were also discussed.engopenAccesschronic heart-failurespontaneously hypertensive-ratstumor-necrosis-factorcholinergic antiinflammatory pathwayrostral ventrolateral medullamuscle-derived interleukin-6randomized controlled-trialssympathetic-nervous-systemleft-ventricular structurecoronary-artery diseasearticleCopyright HINDAWI PUBLISHING CORPORATION10.1155/2014/702473Cell BiologyImmunology1466-1861