Sistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSPCARVALHO, Daniel GleisonVASCONCELOS, Dewton de MoraesSANTOS, Andreia Cristiane RangelLINDOSO, Jose Angelo Lauletta2023-12-152023-12-152023REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, v.56, article ID e03222023, 4p, 20230037-8682https://observatorio.fm.usp.br/handle/OPI/57699Visceral Leishmaniasis (VL) is a potentially fatal disease and may be associated with primary or acquired immunodeficiencies. There are few reports, in the literature, of inborn errors of immunity. Here, we report two cases of VL as a marker of inborn errors of immunity, namely, GATA2 and RAB27A deficiency. Our data suggest that VL patients should be screened for primary immunodeficiency, particularly in cases of VL relapse.engopenAccessVisceral LeishmaniasisPrimary ImmunodeficiencyCellular immunodeficiencyarticleCopyright SOC BRASILEIRA MEDICINA TROPICAL10.1590/0037-8682-0322-2023ParasitologyTropical Medicine