RICARDO RIBEIRO DIAS
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina
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- Answer to ""Key points of reducing neurologic complications in frozen elephant trunk technique""(2015) DIAS, Ricardo Ribeiro; DUNCAN, Jose Augusto
- Nonatherosclerotic Giant Right Coronary Artery Aneurysm(2022) CARDOSO, Lucas Figueredo; DIAS, Ricardo Ribeiro; DEMARCHI, Lea Maria Macruz Ferreira; SILVEIRA, Lucas Molinari Veloso da; MADY, Charles; JATENE, Fabio B.We present an unusual case of a 67-year-old woman with an incidental finding of a cardiac mass on a chest computed tomography. Coronary angiotomography confirmed the diagnosis of right coronary artery aneurysm, with 5.7x5.7 cm. The patient underwent aneurysm resection and coronary bypass surgery, with subsequent histologic study suggestive of arteritis sequelae. Giant coronary artery aneurysms have a high risk of complications and aneurysm exclusion must be beneficial. This is a rare condition that can also be part of a systemic inflammatory disease.
conferenceObject Inhibition of TGfb axis and renin-angiotensin system in human ascending aorta aneurysms(2016) BORGES, L.; ALVARENGA, L. A. A.; FALCAO, R. S. P.; DIAS, R. R.; LACCHINI, S.; GUTIERREZ, P. S.; MICHEL, J. B.bookPart Aneurisma da aorta torárica(2016) SANTIAGO, José Augusto Duncan; DIAS, Ricardo Ribeiro- Aortopulmonary fistula mimicking ductus arteriosus aneurysm on imaging exams(2023) ANDRADE, Alan Rodrigues; CORREIA, Vinicius Machado; SANTIAGO, Jose Augusto Duncan; DIAS, Ricardo Ribeiro; MADRINI JUNIOR, Vagner
- Artéria coronária direita anômala com origem na artéria pulmonar e pericardite constritiva: uma associação inusitada(2013) SILVESTRE, Odilson Marcos; ADAM, Eduardo Leal; MELO, Dirceu Thiago Pessoa de; DIAS, Ricardo Ribeiro; RAMIRES, Felix J. A.; MADY, CharlesThe association of anomalous right coronary artery originating from the pulmonary artery and constrictive pericarditis has never been showed in the literature. We present the first case of this unusual association in a patient with right heart failure. After diagnosis, the patient was referred to surgery and underwent phrenic-to-phrenic pericardiectomy; graft implant of right internal thoracic artery to right coronary artery; and ligation of the anomalous origin of the right coronary artery from the pulmonary artery. Such procedures solved the potential risk of sudden death related to anomalous right coronary artery originating from the pulmonary artery and alleviated the symptoms of heart failure caused by constrictive pericarditis.
- The value of B-type natriuretic peptide as a predictor of mortality in patients with constrictive pericarditis undergoing pericardiectomy(2016) MELO, Dirceu Thiago Pessoa de; MADY, Charles; RAMIRES, Felix Jose Alvarez; DIAS, Ricardo Ribeiro; GUALANDRO, Danielle Menosi; CARAMELLI, Bruno; KALIL FILHO, Roberto; FERNANDES, Fabio
- Transforming growth factor-beta 1 SMAD effectors and medial cell number in ascending aorta diseases(2016) APARECIDA-SILVA, Rosemeire; BORGES, Luciano Figueiredo; KESSLER, Ketty; DIAS, Ricardo Ribeiro; MOREIRA, Luiz Felipe Pinho; KALIL, Jorge; GUTIERREZ, Paulo SampaioIn ascending aorta aneurysms and dissections, the extracellular matrix is degraded. Transforming growth factor (TGF)-beta 1 modulates its synthesis. The production and presence of SMADs, intracellular effectors of TGF-beta 1 signaling, were analyzed in patients with these diseases. To verify whether medial cells are lost, their total numbers were computed. Ascending aorta samples from 19 patients and 18 controls underwent immunoperoxidase reactions to SMADs 2, 3, 4, and 7. Positive and negative cells were counted, and total numbers of cells and positive/total ratios were calculated. Samples from other 14 patients and 7 normal controls were used for the quantification of SMAD3, SMAD4, and SMAD7 mRNA. For SMAD4, both mRNA (2.36 vs. 0.37, P=. 03) and ratio of positive cells (0.94 vs. 0.73, P=. 02) are increased in patients with ascending aortic diseases. SMAD3 mRNA was also increased (1.19 vs. 0.20, P=. 05). The cell ratios of this and the other SMADs, SMAD7 mRNA, and the total cell count did not differ between groups. In conclusion, in ascending aortic aneurysms and dissections, there is an increase in SMAD4, implicated in extracellular matrix production, possibly as an attempt to compensate for extracellular matrix deficiency. Lost medial cells are replaced, since their number is not diminished.
- Acute Myocardial Infarction and Severe Prosthetic Dysfunction after Bentall Procedure(2015) HOTTA, Viviane Tiemi; BARROS, Pedro Gabriel de Melo; GUTIERREZ, Paulo Sampaio; BOLONHEZ, Angela Cristina Pasiani; MATHIAS, Wilson; DIAS, Ricardo Ribeiro
bookPart Dissecção aguda de aorta(2015) MASSOTI, Maria Raquel; DIAS, Ricardo Ribeiro