EDIELLE DE SANT'ANNA MELO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
11 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 11
conferenceObject EFFECT OF INTERMITTENT FASTING ON CYTOKINE (IL-6 AND TNF-ALFA) LEVELS IN KNOCKOUT MICE LDL -/-(2013) AZEVEDO, F. Reis de; MELO, E. Sant'anna; JURADO, M. C.; PASTANA, A. F.; CARAMELLI, B.conferenceObject MORPHOLOGIC ALTERATIONS IN KNOCKOUT LDL-/- MICE AORTA SUBJECT TO DIETARY RESTRICTION(2013) MELO, E. S.; AZEVEDO, F. R.; MONTEIRO, L. H.; JURADO, M. C.; GUTIERREZ, P. S.; CARAMELLI, B.conferenceObject WHAT BARRIERS FOR A REHABILITATION CLINICAL TRIAL CAN TEACH US ABOUT PROFILES OF PATIENTS WITH STROKE IN A DEVELOPING COUNTRY(2013) CONFORTO, A. B.; ANJOS, S. M.; MELLO, E. A.; FERREIRO, K. N.; NAGAYA, E. M.; MELO, E. S.; REIS, F. I.; COHEN, L. G.- Comparison of high-sensitivity cardiac troponin I and T for the prediction of cardiac complications after non-cardiac surgery(2018) GUALANDRO, Danielle M.; PUELACHER, Christian; LURATIBUSE, Giovanna; LAMPART, Andreas; STRUNZ, Celia; CARDOZO, Francisco A.; YU, Pai C.; JAFFE, Allan S.; BARAC, Sanela; BOCK, Lukas; BADERTSCHER, Patrick; LAVALLAZ, Jeanne du Fay de; MARBOT, Stella; SAZGARY, Lorraine; BOLLIGER, Daniel; RENTSCH, Katharina; TWERENBOLD, Raphael; HAMMERER-LERCHER, Angelika; MELO, Edielle S.; CALDERARO, Daniela; DUARTE, Alberto J. S.; LUCCIA, Nelson de; CARAMELLI, Bruno; MUELLER, ChristianBackground: We aimed to directly compare preoperative high-sensitivity cardiac troponin (hs-cTn) I and T concentration for the prediction of major cardiac complications after non-cardiac surgery. Methods: We measured hs-cTnI and hs-cTnT preoperatively in a blinded fashion in 1022 patients undergoing non-cardiac surgery. The primary endpoint was a composite of major cardiac complications including cardiac death, cardiac arrest, myocardial infarction, clinically relevant arrhythmias, and acute heart failure within 30 days. We hypothesized that the type of surgery may impact on the predictive accuracy of hs-cTnI/T and stratified all analyses according to the type of surgery. Results: Major cardiac complications occurred in 108 (11%) patients, 58/243 (24%) patients undergoing vascular surgery and 50/779 (6%, P < .001) patients undergoing non-vascular surgery. Using regulatory-approved 99th percentile cut-off concentrations, preoperative hs-cTnI elevations were less than one-fifth as common as preoperative hs-cTnT elevations (P < .001). Among patients undergoing vascular surgery, preoperative hs-cTnI concentrations, but not hs-cTnT, was an independent predictor of cardiac complications (adjusted odds ratio (aOR) 1.5, 95% confidence interval (95% CI) 1.0-2.1). The area under the receiver-operating characteristics curve (AUC) was 0.67 (95% CI, 0.59-0.75) for hs-cTnI versus 0.59 (95% CI 0.51-0.67, P=.012) for hs-cTnT. In contrast, among patients undergoing non-vascular surgery both preoperative hs-cTnI and hs-cTnT were independent predictors of the primary endpoint (aOR 1.6, 95% CI 1.3-2.0, and aOR 3.0, 95% CI 2.0-4.6, respectively) and showed higher predictive accuracy (AUC 0.77, 95% CI, 0.71-0.83, and 0.79, 95% CI 0.73-0.85, P = ns). Conclusions: Preoperative hs-cTnI and hs-cTnT concentrations predict major cardiac complications after non-vascular surgery, while, in patients undergoing vascular surgery, hs-cTnI may have better accuracy.
conferenceObject THE IMPACT OF BARIATRIC SURGERY ON CARDIOMETABOLIC PROFILE AND ADIPOKINE LEVELS(2016) RABELLO, F. Reis de Azevedo; PEREIRA, S. Santoro dos Santos; CORREA-GIANNELLA, M. L.; GIANNELLA NETO, D.; MELO, E. Sant'Anna; CARAMELLI, B.conferenceObject Predictors of acute heart failure after vascular surgery(2015) GUALANDRO, D. M.; MARCONDES-BRAGA, F. G.; YU, P. C.; CARDOZO, F. A. M.; LLOBET, G. B.; CALDERARO, D.; MELO, E. S.; CASELLA, I. B.; LUCCIA, N.; CARAMELLI, B.conferenceObject Comparison of high-sensitivity cardiac troponin I and T for the prediction of cardiac complications after non-cardiac surgery(2017) GUALANDRO, D. M.; PUELACHER, C.; LURATI-BUSE, G.; STRUNZ, C.; CARDOZO, F. A.; YU, P. C.; JAFFE, A.; TWERENBOLD, R.; HAMMERER-LERCHER, A.; MELO, E. S.; CALDERARO, D.; DUARTE, A. J. S.; LUCCIA, N.; CARAMELLI, B.; MUELLER, C.- Carcinoid Heart Disease: A Case Report and Literature Review(2023) COSTA, Isabela Bispo Santos da Silva; MELO, Edielle de Sant Anna; FURTADO, Armando; SOBRAL-ALVES, Juliana Barbosa; RIZK, Stephanie Itala; BENVENUTI, Luiz Alberto; ROCHITTE, Carlos E.; BRANDAO, Carlos Manuel de Almeida; POMARENTZEFF, Pablo Maria; BITTAR, Cristina Salvadori; GALAS, Filomena Regina Barbosa Gomes; AULER JUNIOR, Jose Otavio Costa; HOFF, Paulo Marcelo Gehm; KALIL FILHO, Roberto; JATENE, Fabio Biscegli; HAJJAR, Ludhmila Abrahao
conferenceObject EFFECT OF INTERMITTENT FASTING ON CYTOKINE (IL-6 AND TNF-?) LEVELS IN KNOCKOUT MICE LDL -/-(2013) AZEVEDO, F. Reis de; MELO, E. Sant'anna; JURADO, M. C.; PASTANA, A. F.; CARAMELLI, B.conferenceObject DIET AND CARDIOVASCULAR RISK: THE EFFECTS OF INTERMITTENT FASTING ON THE SYSTEMIC AND ARTHERIAL WALL INFLAMMATION IN MURINE A MODEL OF ACCELERATED ATHEROGENESIS(2015) MELO, E. S.; MELE, M.; MONTEIRO, L. H.; AZEVEDO, F. R.; MEIRELLES, G. V.; GIOVAMBATTISTA, P.; CARAMELLI, B.