FRANCISCO AKIRA MALTA CARDOZO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
35 resultados
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conferenceObject Incidence and outcome of perioperative myocardial injury after noncardiac surgeries diagnosed by different high sensitivity troponin assays(2018) GUALANDRO, D. M.; PUELACHER, C.; CARAMELLI, B.; LURATIBUSE, G.; CARDOZO, F. A.; CALDERARO, D.; YU, P. C.; SAZGARY, L.; HIDVEGI, R.; STRUNZ, C.; BOLLIGER, D.; OSSWALD, S.; MUELLER, C.- Advances in medical technology and new digital educational platforms(2019) MADRINI JUNIOR, Vagner; CARDOZO, Francisco Akira Malta; GOMES, Brenno Rizerio; ALMEIDA, Mozar Suzigan de; SCUDELER, Thiago Luis; SCARPA, Bruna Romanelli
conferenceObject Acute heart failure after non-cardiac surgery: incidence, phenotypes, determinants and outcomes(2022) GUALANDRO, D. M.; PUELACHER, C.; CHEW, M. S.; ANDERSSON, H.; BUSE, G. Lurati; GLARNER, N.; MUELLER, D.; CARDOZO, F. A. M.; BURRI, K.; MORK, C.; WUSSLER, D.; BOLLIGER, D.; OSSWALD, S.; CARAMELLI, B.; MUELLER, C.- Long-term outcomes of perioperative myocardial infarction/injury after non-cardiac surgery(2023) PUELACHER, Christian; GUALANDRO, Danielle M.; GLARNER, Noemi; BUSE, Giovanna Lurati; LAMPART, Andreas; BOLLIGER, Daniel; STEINER, Luzius A.; GROSSENBACHER, Mario; BURRI-WINKLER, Katrin; GERHARD, Hatice; KAPPOS, Elisabeth A.; CLERC, Olivier; BINER, Laura; ZIVZIVADZE, Zaza; KINDLER, Christoph; HAMMERER-LERCHER, Angelika; FILIPOVIC, Miodrag; CLAUSS, Martin; GURKE, Lorenz; WOLFF, Thomas; MUJAGIC, Edin; BILICI, Murat; CARDOZO, Francisco A.; OSSWALD, Stefan; CARAMELLI, Bruno; MUELLER, ChristianAims Perioperative myocardial infarction/injury (PMI) following non-cardiac surgery is a frequent cardiac complication. Better understanding of the underlying aetiologies and outcomes is urgently needed.Methods and results Aetiologies of PMIs detected within an active surveillance and response programme were centrally adjudicated by two independent physicians based on all information obtained during clinically indicated PMI work-up including cardiac imaging among consecutive high-risk patients undergoing major non-cardiac surgery in a prospective multicentre study. PMI aetiologies were hierarchically classified into 'extra-cardiac' if caused by a primarily extra-cardiac disease such as severe sepsis or pulmonary embolism; and 'cardiac', further subtyped into type 1 myocardial infarction (T1MI), tachyarrhythmia, acute heart failure (AHF), or likely type 2 myocardial infarction (lT2MI). Major adverse cardiac events (MACEs) including acute myocardial infarction, AHF (both only from day 3 to avoid inclusion bias), life-threatening arrhythmia, and cardiovascular death as well as all-cause death were assessed during 1-year follow-up. Among 7754 patients (age 45-98 years, 45% women), PMI occurred in 1016 (13.1%). At least one MACE occurred in 684/7754 patients (8.8%) and 818/7754 patients died (10.5%) within 1 year. Outcomes differed starkly according to aetiology: in patients with extra-cardiac PMI, T1MI, tachyarrhythmia, AHF, and lT2MI 51%, 41%, 57%, 64%, and 25% had MACE, and 38%, 27%, 40%, 49%, and 17% patients died within 1 year, respectively, compared to 7% and 9% in patients without PMI. These associations persisted in multivariable analysis.Conclusion At 1 year, most PMI aetiologies have unacceptably high rates of MACE and all-cause death, highlighting the urgent need for more intensive treatments.Study registration.
book Os 100 trials que mudaram a história da cardiologia(2019) SCUDELER, Thiago Luis; GOMES, Brenno Rizerio; MADRINI JUNIOR, Vagner; CARDOZO, Francisco Akira Malta; RAMIRES, José Antonio Franchini; KALIL FILHO, RobertobookPart Anticoagulação no idoso(2022) BISCAIA, Gabriela Tanajura; CARDOSO, Francisco Akira Malta; CRENITTE, Milton Roberto FurstbookPart O exame cardíaco(2021) CARDOZO, Francisco Akira Malta; CARAMELLI, Bruno- Impact of the period of the day on all-cause mortality and major cardiovascular complications after arterial vascular surgeries(2023) ARTIOLI, Thiago; GUALANDRO, Danielle Menosi; CARDOZO, Francisco Akira Malta; ROJAS, Maria Carmen Escalante; CALDERARO, Daniela; YU, Pai Ching; CASELLA, Ivan Benaduce; LUCCIA, Nelson de; CARAMELLI, BrunoBackgroundConflicting results are reported about daytime variation on mortality and cardiac outcomes after non-cardiac surgeries. In this cohort study, we evaluate whether the period of the day in which surgeries are performed may influence all-cause mortality and cardiovascular outcomes in patients undergoing non-cardiac arterial vascular procedures. Methods1,267 patients who underwent non-cardiac arterial vascular surgeries between 2012 and 2018 were prospectively included in our cohort and categorized into two groups: morning (7 a.m. to 12 a.m., 79%) and afternoon/night (12:01 p.m. to 6:59 a.m. in the next day, 21%) surgeries. Primary endpoint was all-cause mortality within 30 days and one year. Secondary endpoints were the incidence of perioperative myocardial injury/infarction (PMI), and the incidence of major adverse cardiac events (MACE, including acute myocardial infarction, acute heart failure, arrhythmias, cardiovascular death) at hospital discharge. ResultsAfter adjusting for confounders in the multivariable Cox proportional regression, all-cause mortality rates at 30 days and one year were higher among those who underwent surgery in the afternoon/night (aHR 1.6 [95%CI 1.1-2.3], P = 0.015 and aHR 1.7 [95%CI 1.3-2.2], P < 0.001, respectively). Afternoon/night patients had higher incidence of PMI (aHR 1.4 [95%CI 1.1-1.7], P < 0.001). There was no significant difference in the incidence of MACE (aHR 1.3 [95%CI 0.9-1.7], P = 0.074). ConclusionsIn patients undergoing arterial vascular surgery, being operated in the afternoon/night was independently associated with increased all-cause mortality rates and incidence of perioperative myocardial injury/infarction.
conferenceObject Incidence and outcome of perioperative myocardial infarction/injury after non-cardiac surgeries diagnosed by high-sensitivity cardiac troponin I(2019) GUALANDRO, D. M.; PUELACHER, C.; HIDVEGI, R.; CARDOZO, F. A.; MARBOT, S.; YU, P. C.; VOGT, R.; CALDERARO, D.; GUECKEL, J.; STRUNZ, C.; BOLLIGER, D.; RENTSCH, K.; CARAMELLI, B.; MUELLER, C.conferenceObject Impact of the period of the day on mortality and major cardiovascular complications after vascular surgeries(2020) CARDOZO, F. A. M.; ARTIOLI, T.; CARAMELLI, B.; CALDERARO, D.; YU, P. C.; ROJAS, M. C. E.; CASELLA, I. B.; LUCCIA, N. De; GUALANDRO, D. M.