CYNTHIA ROTHSCHILD
Índice h a partir de 2011
0
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Acquired von willebrand syndrome secondary to monoclonal gammopathy of undetermined significance: long-term remission after treatment with bortezomib(2023) SALDANHA, Artur; VEIGA, Maria Eduarda; OKAZAKI, Erica; ROTHSCHILD, Cynthia; MARTINEZ, Gracia; ROCHA, Vanderson; ORSI, Fernanda A.; VILLACA, PaulaMonoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder that can precede the diagnosis of multiple myeloma. MGUS is characterized by the presence of a monoclonal paraprotein without evidence of multiple myeloma or other lymphoplasmacytic malignancies. Even though MGUS is an asymptomatic condition that does not require management strategies other than periodic follow-up to prevent complications, secondary nonmalignant diseases may arise, requiring control of the plasma cell clone. Acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder that occurs in patients with no prior personal or family history of bleeding. It is associated with several other disorders, such as neoplasia, mainly hematological (including MGUS and other lymphoproliferative disorders), autoimmune, infectious and cardiac diseases. At diagnosis, patients usually present with cutaneous and mucosal bleeding, including gastrointestinal bleeding. Here, we report a case of a patient with MGUS who developed AVWS after one year of follow-up. The patient was refractory to glucocorticoids and cyclophosphamide and achieved remission only after monoclonal paraprotein was eradicated following treatment with bortezomib and dexamethasone. Our report sdemonstrates that, for refractory cases, eradication of the monoclonal paraprotein may be necessary to treat bleeding complications due to MGUS-associated AVWS.
- Safety and efficacy of splenectomy for the treatment of chronic immune thrombocytopenia(2022) SALDANHA, Artur; ORSI, Fernanda A.; OKAZAKI, Erica; ROTHSCHILD, Cynthia; PRESTES, Paula; STEFANELLO, Bianca; ALVES, Lucas; ROCHA, Vanderson; VILLACA, Paula
conferenceObject Educational and financial impact of a recommendation on cancer-associated thrombosis (CAT) management: experience of a Brazilian oncological Public Hospital for adults(2021) ROTHSCHILD, C.; DIZ, M. P. E.; ZERATI, A. E.; SABANAI, A. H.; ALBUQUERQUE, G. M.; TAKAHASHI, T. T.; BRANDAO, A. A. G. S.; PEREIRA, J.; ROCHA, V.- Extracellular Vesicles As Markers of Inflammation and Hypercoagulability during the First Month of Sars-COV-2 Infection in Outpatients and Hospitalized Patients(2022) BARION, Barbara Gomes; ROCHA, Tania Rubia; Ho Yeh-Li; VILLACA, Paula Ribeiro; MAZETTO, Bruna M.; OKASAKI, Erica; STEFANELLO, Bianca; ROTHSCHILD, Cynthia; ROCHA, Vanderson Gomes; ORSI, Fernanda Andrade
conferenceObject Pharmaceutical vigilance and education: the first 6 months of a new anticoagulant at a Brazilian cancer institute(2021) ROTHSCHILD, C.; SABANAI, A. H.; SANTOS, A. A.; SOUSA, C. O.; SIQUEIRA, R. S.; FERRETTI, T.; BRANDAO, A. A. G. S.; DIZ, M. P. E.; PEREIRA, J.; ROCHA, V.