ANA LUCIA MONTEIRO GUIMARAES
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bookPart Farmacodermias(2022) GUIMARãES, Ana Lúcia Monteiro; PINCELLI, Marcella Soares; NICO, Marcello Menta SimonsenbookPart Farmacodermias(2020) GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta Simonsen- Aphtha Major Perianalis(2019) GUIMARAES, Ana Lucia Monteiro; LOURENCO, Silvia Vanessa; NICO, Marcello Menta Simonsen
- Extensive scalp ulcer secondary to delusional infestation treated with antipsychotics and scalp reconstruction(2020) PINCELLI, M. S.; GUIMARARES, A. L. M.; MILCHESKI, D. A.; DWAN, A. J.; NICO, M. M. S.
- Etonogestrel-releasing contraceptive implant in a patient using thalidomide for the treatment of erythema nodosum leprosum: a case report(2022) FERREIRA-FILHO, Edson Santos; BAHAMONDES, Luis; DUARTE, Daniele Coelho; GUIMARAES, Ana Lucia Monteiro; ALMEIDA, Patricia Goncalves de; SOARES-JUNIOR, Jose Maria; BARACAT, Edmund Chada; SORPRESO, Isabel Cristina EspositoIntroduction Thalidomide is an immunomodulatory drug and first choice in the treatment of erythema nodosum leprosum. Given its teratogenic potential, it is essential that an effective contraceptive method is used, especially a long-acting reversible contraceptive (LARC) method. The subdermal etonogestrel (ENG)-releasing implant is an adequate method due to the high effectiveness and long-term use. However, interaction between thalidomide and ENG has not been well documented. Concern arises because thalidomide interacts with cytochrome P450 (CYP450) enzymes that metabolize sexual steroids. AIM: We aimed to study the effectiveness and safety of the ENG-implant in a thalidomide user. Methods Case report of a sexually active 21-year-old patient with both Hansen's disease and leprosy reaction type 2 treated with thalidomide requiring effective contraception. Follow-up was up to 36 months after implant placement. Results Contraception with ENG-implant was effective and safe, based on clinical parameters (reduction of menstrual flow and cervical mucus thickening) and laboratory parameters (gonadotropins and sexual steroids). Conclusion To the best of our knowledge, this is the first case reported which presents a patient in simultaneous use of thalidomide and ENG-implant. Although this case report preliminary supports effectiveness and safety of ENG-implant as a contraceptive option in women using thalidomide, rigorous drug-drug interaction research is needed to better characterize the interaction between thalidomide and the ENG-implant.
- Influence of Criteria Used in Determining Prevalence of Metabolic Syndrome (NCEP-ATPIII versus IDF) in Patients with Intermittent Claudication(2014) ZERATI, Antonio Eduardo; GUIMARAES, Ana Lucia Monteiro; CARVALHO, Heitor Andrei Miranda de; SAES, Glauco Fernandes; RAGAZZO, Luciana; WOLOSKER, Nelson; LUCCIA, Nelson deBackground: In patients with peripheral arterial disease, metabolic syndrome is associated with less favorable evolution of intermittent claudication. Methods: The aims of this study were to determine the prevalence of metabolic syndrome in claudicant patients using the IDF and the NCEP-ATPIII criteria, and to assess the level of agreement between the two definitions. Results: In this cross-sectional study, 200 consecutive patients with intermittent claudication (65% male) were classified with or without metabolic syndrome according both criteria. The kappa coefficient was used to assess the level of agreement. Prevalence of metabolic syndrome was 60.5% when using the NCEP-ATPIII definition and 66.5% when using the IDF definition (P = 0.088). Among men, the prevalence of MetS was 55.4% according to the NCEP-ATPIII and 63.1% according to the IDF (P = 0.110) and, among women, 70.0% according to the NCEP-ATPIII and 72.9% according to the IDF (P = 0.754). Conclusion: Although the prevalence rates were similar, the reliability analysis showed that the agreement was substantial only among women and just moderate in the total population and among men.
bookPart Farmacodermias(2019) GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta Simonsen- Dermatoscopic features of 67 excised melanocytic lesions in patients at high risk of cutaneous malignant melanoma in a Brazilian hospital(2022) ABED, N. M.; AVANCINI, J.; FERREIRA, P. S.; GUIMARãES, A. L. Monteiro; FESTA NETO, C.
bookPart Dermatoses agudas(2022) PINCELLI, Marcella Soares; GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta SimonsenbookPart Dermatoses agudas(2021) PINCELLI, Marcella Soares; GUIMARãES, Ana Lúcia Monteiro; NICO, Marcello Menta Simonsen