ALEXANDRA SIQUEIRA COLOMBO PORTUGAL

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SVFOFITO-62, Hospital Universitário

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  • article 3 Citação(ões) na Scopus
    Prevalence and Factors Associated with Sarcopenia in Hospitalized Elderly Patients
    (2022) BORGES, Rodrigo Cerqueira; CORREA, Daniel Imay; CORREA, Lourdes Jaqueline Sampaio; COLOMBO, Alexandra Siqueira; CARVALHO, Celso Ricardo Fernandes
    Background/Purpose: Sarcopenia is a public health problem; however, it remains poorly evaluated during hospitalization. The aim of this study was to evaluate the prevalence of sarcopenia and the factors associated with this condition in hospitalized elderly patients Methods: A total of 122 elderly individuals were evaluated in this case-control study (61=hospitalized and 61=non-hospitalized). Sarcopenia was defined and evaluated according to the criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). The Charlson comorbidity index, geriatric depression scale, body mass index (BMI), Barthel Index, Mini-Mental State Examination (MMSE), Lawton-Brody index, and Mini Nutritional Assessment Instrument-Short Form (MNA-SF) were also used for the evaluations. Results: The prevalence of sarcopenia was 38% in hospitalized patients compared to 11% in controls. Hospitalized elderly patients showed a significant reduction in functionality, muscle strength, and mental and nutritional status compared to the controls. Sarcopenic patients were older, had a lower BMI, and obtained worse MMSE results than non-sarcopenic individuals. There was an association between the MMSE results and the BMI in patients with sarcopenia that was independent of the group. Conclusion: Sarcopenia is highly prevalent in hospitalized elderly individuals, and it is associated with cognitive state and BMI.
  • article 60 Citação(ões) na Scopus
    Physical activity, muscle strength, and exercise capacity 3 months after severe sepsis and septic shock
    (2015) BORGES, Rodrigo Cerqueira; CARVALHO, Celso R. F.; COLOMBO, Alexandra Siqueira; BORGES, Mariucha Pereira da Silva; SORIANO, Francisco Garcia
    To quantify the physical activity in daily life (PADL), muscle strength, and exercise capacity in the short and medium term in survivors of severe sepsis and septic shock. Prospective cohort study with a follow-up from hospital admission to 3 months after hospital discharge. Seventy-two patients admitted to the ICU for severe sepsis or septic shock and a control group of healthy sedentary subjects (n = 50) were enrolled. All patients had their PADL quantified by an accelerometer during their hospital stay and 3 months after. Exercise capacity and handgrip and quadriceps muscle strength were also evaluated. During hospitalization, patients spent the majority of their time inactive in a lying or sitting position (90 +/- A 34 % of daily time). Physical inactivity was partially reduced 3 months after (58 +/- A 20 % of daily time). However, the time patients spent walking was only 63 % of the time reported for healthy subjects. Patients also showed lower movement intensity when compared with controls (2.1 +/- A 0.3 vs 2.5 +/- A 0.4 m/s(2)). At hospital discharge, muscle strength and exercise capacity were approximately 54 % of the predicted value, and these parameters showed significant increase in patients 3 months after (70 % of predicted value). Multivariable analysis demonstrated that the use of systemic corticosteroids and hospitalization time negatively influenced quadriceps strength and exercise capacity at the time of hospital discharge. Our results suggest that survivors of sepsis admitted to the ICU have a substantial reduction in physical activity, exercise capacity, and muscle strength compared to healthy subjects that persist even 3 months after hospital discharge.
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    Physiotherapy indication and accomplishment at ICU
    (2013) SILVEIRA, Leda; PEZ, Mauro; NOGUEIRA, Priscila; FURLAN, Sofia; COLOMBO, Alexandra