PAULA SILVA FERREIRA
Projetos de Pesquisa
Unidades Organizacionais
22 resultados
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Agora exibindo 1 - 10 de 22
- Extensive cutaneous involvement by dermatomyositis: Report of six cases and review of the literature(2020) MIYASHIRO, Denis; ARNONE, Marcelo; FERREIRA, Paula Silva; ROMITI, Ricardo; SANCHES, Jose Antonio
- Longitudinal melanonychia due to voriconazole therapy during treatment of chromoblastomycosis(2018) CRIADO, P. R.; COSENZA, F. D.; JUNIOR, W. B.; FERREIRA, P. S.
- Dermatoscopy: an auxiliary resource for the diagnosis of poroid neoplasms(2018) SARAIVA, Maria Isabel Ramos; FERREIRA, Paula Silva; AVANCINI, Joao; VALENTE, Neusa Yuriko SakaiPoroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into dassic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Association of histological subtypes occurs in more than 25% of cases. We report a case of a combined poroid neoplasia of classical poroma and poroid hidradenoma, reviewing its dermatoscopic features.
bookPart Afecções das mucosas(2019) WU, Isabelle I. Hue; FERREIRA, Paula Silva; SANTI, Claudia Giuli; NICO, Marcello Menta Simonsen- Multiple Filiform Keratoses and Nodules in a 10-Year-Old Girl(2013) FERREIRA, Paula Silva; VALENTE, Neusa Yuriko Sakai; NICO, Marcello Menta Simonsen
bookPart Infecções bacterianas(2019) FERREIRA, Paula Silva- In Vivo Reflectance Confocal Microscopy of Adnexal Tumors: Evaluation of Trichoepithelioma, Sebaceoma, and Fibrofolliculoma(2022) ROSALES-DURAN, Sharon; RICAURTE-JIMENEZ, Marcela; FERREIRA, Paula S.; SANGUEZA, Martin; V, Silvia Lourenco; NICO, Marcello M. S.Cutaneous adnexal tumors are benign and malignant neoplasms that undergo morphological differentiation into cutaneous adnexa, comprising pilosebaceous, eccrine, or apocrine units. Reflectance confocal microscopy is a noninvasive diagnostic method that enables in vivo visualization of tissues at a similar resolution as conventional histopathology. The use of this method in skin imaging over the past several years has improved dermatological diagnoses, potentiating its wide application, especially for benign and malignant skin tumors. We describe the use of reflectance confocal microscopy in cases of trichoepithelioma, sebaceoma, and fibrofolliculoma and correlate the resulting clinical, histopathological, and confocal microscopy images.
bookPart Pústula(2019) FERREIRA, Paula Silva- Pigmented Kamino bodies: a little-known histological finding. Prevalence in 19 cases of Reed nevus(2017) ANTUNES, Ana Caroline Barreto; FERREIRA, Paula Silva; VESPOLI, Aline Caixeta Guimaraes; VALENTE, Neusa Yuriko SakaiThe present study aimed to determine the prevalence of Kamino bodies in Reed nevus, since most studies to date show conflicting data on this issue. This was a retrospective observational study, in which the histopathology of 19 Reed nevus lesions were reviewed. The slides were stained by hematoxylin and eosin and periodic acid-Schiff, with a special focus placed on the identification of Kamino bodies. Some clinical data were also collected. The median patient age was 12 years (range of 2 to 58). The women to men ratio was 5:4. Lesions were located on different parts of the body. Kamino bodies were found in eleven lesions (57.89%). five showed pigmented Kamino bodies (26.31%), four non-pigmented Kamino bodies (21,05%), and 2 (10.52%) had both. Kamino bodies, pigmented or not, are a common histological finding in Reed nevus and may well represent a good marker to differentiate these from malignant melanomas.
- Reflectance confocal microscopy (RCM)-based criteria for progression of lower-lip squamous cell carcinoma: A prospective study(2022) FERREIRA, Paula Silva; ROCHA, Lilian; BEZERRA, Ana Patricia Carneiro; NICO, Marcello Menta Simonsen; LOURENCO, Silvia VanessaBackground: Actinic cheilitis (AC) presents as a diffuse clinical-histopathological alteration throughout the lower lip. Objectives: To analyze AC lesions using reflectance confocal microscopy (RCM) and evaluate criteria for the early diagnosis of incipient squamous cell carcinoma (SCC). Methods: This prospective study comprised cases of clinically diagnosed AC. RCM was performed over the entire extension of the lower lip. The sites that showed the highest degree of morphological alteration by RCM, according to established criteria for AC and SCC, were biopsied. The RCM findings and histopathology were correlated to establish the precise and early diagnosis of SCC. Results: A total of 61 cases that had been clinically diagnosed with AC were included. The RCM findings that correlated independently with SCC were: nonedged papillae (sensitivity 84% and specificity 88%, p < 0.0001, and OR 42), cell-filled papillae (sensitivity 82% and specificity 93%, p < 0.0001, and OR 71.3), inflammation (sensitivity 68% and specificity 68%, p = 0.0163, and OR 4.8), large and roundish cells in the lamina propria (sensitivity 65% and specificity 100%, p < 0.0001, and OR infinity), and nests in the lamina propria (sensitivity 54% and specificity 100%, p < 0.0001, and OR infinity). An independent histopathological analysis classified the cases as partial epithelial dysplasia (25 cases, 41%) and SCC (36, 59%), and in 57 cases (94%), the results agreed with the categorization that was rendered by the RCM exam. Conclusions: RCM can be used to monitor AC cases, guide the biopsy site, and identify the early progression of AC to SCC with good sensitivity and specificity.
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