ANA MARIA RIBEIRO DE CASTRO DUARTE
Projetos de Pesquisa
Unidades Organizacionais
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- Residual malaria of Atlantic Forest systems and the influence of anopheline fauna(2021) FERREIRA, Lucas Mendes; REZENDE, Helder Ricas; BUERY, Julyana Cerqueira; SILVA, Leonardo Santana da; FIGUEIREDO, Thaysa Carolina Cantanhede; FUX, Blima; DUARTE, Ana Maria Ribeiro de Castro; CERUTTI JUNIOR, CrispimIn Brazil, the Amazon region comprises 99.5% of the reported malaria cases. However, another hotspot of the disease is the Atlantic Forest regions, with the sporadic occurrence of autochthonous human cases. In such context, this study sought to investigate the role of anopheline mosquitoes (Diptera: Culicidae) in the residual malaria transmission in Atlantic Forest areas. Two rural areas in the Espirito Santo state were the surveyed sites. Mosquitoes were captured using Shannon trap and CDC light traps and identified into species based on morphological characters. Ecological indexes (Shannon-Wiener diversity, Simpson's dominance, Pielou equability, and Sorensen similarity) were the tools used in the anopheline fauna characterization and comparison along with the two explored areas. The assessment of the sampling adequacy in the studied areas was possible through the generation of a species accumulation curve. A correlation test verified the influence of climatic variables on the anopheline species abundance. A total of 1471 female anopheline mosquitoes were collected from May 2019 to April 2020, representing 13 species. The species richness was higher in Valsugana Velha (hypo-endemic) than in Alto Caparao (non-endemic). There was a significant variation in the species abundance between Valsugana Velha (n = 1438) and Alto Caparao (n = 33). The most abundant species was Anopheles (Kerteszia) cruzii complex Dyar and Knab, 1908 representing 87% of the total anophelines collected. These results suggest that the Plasmodium spp. circulation in Brazilian Atlantic Forest areas occurs mainly due to the high frequency of Anopheles (K.) cruzii complex, considered the principal vector of simian and human malaria in the region.
- Atlantic Forest Malaria: A Review of More than 20 Years of Epidemiological Investigation(2021) BUERY, Julyana Cerqueira; ALENCAR, Filomena Euridice Carvalho de; DUARTE, Ana Maria Ribeiro de Castro; LOSS, Ana Carolina; VICENTE, Creuza Rachel; FERREIRA, Lucas Mendes; FUX, Blima; MEDEIROS, Marcia Melo; CRAVO, Pedro; AREZ, Ana Paula; CERUTTI JUNIOR, CrispimIn the south and southeast regions of Brazil, cases of malaria occur outside the endemic Amazon region near the Atlantic Forest in some coastal states, where Plasmodium vivax is the recognized parasite. Characteristics of cases and vectors, especially Anopheles (Kerteszia) cruzii, raise the hypothesis of a zoonosis with simians as reservoirs. The present review aims to report on investigations of the disease over a 23-year period. Two main sources have provided epidemiological data: the behavior of Anopheles vectors and the genetic and immunological aspects of Plasmodium spp. obtained from humans, Alouatta simians, and Anopheles spp. mosquitoes. Anopheles (K.) cruzii is the most captured species in the forest canopy and is the recognized vector. The similarity between P. vivax and Plasmodium simium and that between Plasmodium malariae and Plasmodium brasilianum shared between simian and human hosts and the involvement of the same vector in the transmission to both hosts suggest interspecies transfer of the parasites. Finally, recent evidence points to the presence of Plasmodium falciparum in a silent cycle, detected only by molecular methods in asymptomatic individuals and An. (K.) cruzii. In the context of malaria elimination, it is paramount to assemble data about transmission in such non-endemic low-incidence areas.
- Ongoing host-shift speciation in Plasmodium simium(2021) OLIVEIRA, Thais C. de; RODRIGUES, Priscila T.; DUARTE, Ana Maria R. C.; RONA, Luisa D. P.; FERREIRA, Marcelo U.Plasmodium simium, a malaria parasite that infects platyrrhine monkeys and humans in the New World, is nearly identical to Plasmodium vivax. Recent genomic comparative analyses of these sister species have identified elevated divergence in a gene that may underlie P. simium adaptation to non-human primates during its gradual speciation process.