ANA CRISTINA SAYURI TANAKA

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5
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Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

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Agora exibindo 1 - 10 de 28
  • conferenceObject
    GOING AGAINST THE ODDS - A CASE OF SUCCESS IN A PREGNANT PATIENT WITH COMPLEX CONGENITAL HEART DISEASE
    (2021) KORMANN-MOREIRA, Mylena Cristina; MARTINS, Ana Vitoria Vitoreti; LEMOUCHE, Stephanie Ondracek; SANTANA, Marcela Devido; TANAKA, Ana Cristina Sayuri; ZORZANELLI, Leina; THOMAZ, Ana Maria; IKARI, Nana Miura; AVILA, Walkiria Samuel
  • bookPart
    Principais arritmias
    (2018) SHIMODA, Mônica Satsuki; TANAKA, Ana Cristina Sayuri
  • article 3 Citação(ões) na Scopus
    Type III glycogen storage disease mimicking hypertrophic cardiomyopathy
    (2012) SALEMI, Vera Maria Cury; DEMARCHI, Lea Maria Macruz Ferreira; CABEDA, Estevan Vieira; WAGENFUEHR, Jaqueline; TANAKA, Ana Cristina
  • article 32 Citação(ões) na Scopus
    CXCL9/Mig Mediates T cells Recruitment to Valvular Tissue Lesions of Chronic Rheumatic Heart Disease Patients
    (2013) FAE, Kellen C.; PALACIOS, Selma A.; NOGUEIRA, Luciana G.; OSHIRO, Sandra E.; DEMARCHI, Lea M. F.; BILATE, Angelina M. B.; POMERANTZEFF, Pablo M. A.; BRANDAO, Carlos; THOMAZ, Petronio G.; REIS, Maxwell dos; SAMPAIO, Roney; TANAKA, Ana C.; CUNHA-NETO, Edecio; KALIL, Jorge; GUILHERME, Luiza
    Rheumatic fever (RF) is an autoimmune disease triggered by Streptococcus pyogenes infection frequently observed in infants from developing countries. Rheumatic heart disease (RHD), the major sequel of RF, leads to chronic inflammation of the myocardium and valvular tissue. T cells are the main population infiltrating cardiac lesions; however, the chemokines that orchestrate their recruitment are not clearly defined. Here, we investigated the expression of chemokines and chemokine receptors in cardiac tissue biopsies obtained from chronic RHD patients. Our results showed that CCL3/MIP1 alpha gene expression was upregulated in myocardium while CCL1/I-309 and CXCL9/Mig were highly expressed in valvular tissue. Auto-reactive T cells that infiltrate valvular lesions presented a memory phenotype (CD4(+)CD45RO(+)) and migrate mainly toward CXCL9/Mig gradient. Collectively, our results show that a diverse milieu of chemokines is expressed in myocardium and valvular tissue lesions and emphasize the role of CXCL9/Mig in mediating T cell recruitment to the site of inflammation in the heart.
  • bookPart
    Cardiopatias congênitas no adulto
    (2018) TANAKA, Ana Cristina Sayuri; ZORZANELLI, Leína; IKARI, Nana Miura
  • conferenceObject
    RESTRICTIVE AND HYPERTROPHIC CARDIOMYOPATHIES AS INDICATION FOR HEART TRANSPLANTATION: CLINICAL OUTCOME IN A SINGLE CENTER
    (2013) TANAKA, Ana Cristina; MIURA, Nana; THOMAZ, Ana Maria; AIELLO, Vera Demarchi; BENEVENUTI, Luiz; TAVARES, Glaucia; NOMURA, Cesar; JATENE, Marcelo Biscegli; AZEKA, Estela
    PURPOSE: The purpose of this study was evaluate the prevalence and outcome of restrictive and hypertrophic cardiomyopathies in a cohort of pediatric heart transplantation. METHOD: To evaluate the prevalence and clinical outcome of children with restrictive and hypertrophic cardiomyopathies submitted heart transplantation. RESULTS: From october 1992 to 2012, 115 patients were submitted heart transplantation. 120 transplants were performed at Heart Institute (InCor) University São Paulo Medical School. Seventeen (14,7%) of these patients hat restrictive cardiomyopathy/hypertrophic cardiomyopathy and have undergone to heart transplantation. The mean age was 10,4 years. Survival was 76,4%. Follow-up period ranged from 26 days to 6,6 years. CONCLUSION: Restrictive and hypertrophic cardiomyopathies can be an indication for heart transplantation a favorable outcome.
  • article 11 Citação(ões) na Scopus
    I DIRETRIZ DE INSUFICIÊNCIA CARDÍACA (IC) E TRANSPLANTE CARDÍACO, NO FETO, NA CRIANÇA E EM ADULTOS COM CARDIOPATIA CONGÊNITA, DA SOCIEDADE BRASILEIRA DE CARDIOLOGIA
    (2014) AZEKA, E.; JATENE, M. B.; JATENE, I. B.; HOROWITZ, E. S. K.; BRANCO, K. C.; SOUZA NETO, J. D.; MIURA, N.; MATTOS, S.; AFIUNE, J. Y.; TANAKA, A. C.; SANTOS, C. C. L.; GUIMARAES, I. C. B.; MANSO, P. H.; PELLIZARI, R. C. R. S.; SANTOS, M. V. C.; THOMAZ, A. M.; CRISTOFANI, L. M.; RIBEIRO, A. C. L.; KULIKOWSKI, L. D.; SAMPAIO, M. C.; PEREIRA, A. C.; SOARES, A. M.; SOARES JUNIOR, J.; OH, G. H. Y.; MOREIRA, V; MOTA, C. C. C.; AFIUNE, C. M. C.; PEDRA, C.; PEDRA, S.; PEDROSA, A.; GUIMARAES, V; CANEO, L. F.; FERREIRO, C. R.; CAVALHEIRO FILHO, C.; STEFANELLO, B.; NEGRAO, C. E.; TURQUETTO, A. L. R.; MESQUITA, S. M. F.; MAEDA, W. T.; ZORZANELLI, L.; PANAJOTOPOLOS, N.; SIQUEIRA, A. W. S.; GALAS, F. R. B.; HAJJAR, L. A.; BENVENUTI, L. A.; VINCENZI, P.; ODONE, V; LOPES, M. H.; V, T. M. Strabelli; FRANCHI, S. M.; TAKEUTI, A. D.; DUARTE, M. F.; LEON, R. G. P.; HERMIDA, R. P. M.; SORPRESO, I. C. E.; SOARES JUNIOR, J. M.; MELO, N. R.; BARACAT, E. C.; BORTOLOTTO, M. R. F. L.; SCANAVACCA, M.; SHIMODA, M. S.; FORONDA, G.; ROMANO, B. W.; SILVA, D. B.; OMURA, M. M.; BARBEIRO, C. P. M.; VINHOLE, A. R. G.; PALOMO, J. S. H.; GONCALVES, M. A. B.; REIS, I. C. F.; OLIVEIRA, L. G.; RIBEIRO, C. C.; ISOSAKI, M.; VIEIRA, L. P.; FELTRIM, M. I. Z.; MANOEL, L. A.; ABUD, K. C. O.; PASCHOTTO, D. R.; NEVES, I. L. I.; SENAHA, L. E.; GARCIA, A. C. C. N.; CIPRIANO, S. L.; SANTOS, V. C.; FERRAZ, A. S.; MOREIRA, A. E. L. C.; PAULO, A. R. S. A. De; DUQUE, A. M. P. C.; TRINDADE, E.; BACAL, F.; AULER JUNIOR, J. O. C.; ALMEIDA, D. R.
  • conferenceObject
    SIBLINGS WITH RESTRICTIVE SYNDROME AND HYPERTROPHIC CARDIOMYOPATHY: A RARE CASE OF SUCCESSFUL HEART TRANSPLANTATION
    (2013) AZEKA, Estela; KAWASAKA, Ana Laura B. C.; TANAKA, Ana Cristina S.; PEREIRA, Alexandre C.; AIELLO, Vera D.; JATENE, Marcelo B.
    PURPOSE: To report the cases of siblings with restrictive syndrome who underwent heart transplantation and whose hearts had histological characteristics of hypertrophic cardiomyopathy (HCM). METHOD: Case1) A 7 year-old boy with recurrent pneumonias and cardiomegaly. Echocardiography showed features of restrictive cardiomyopathy. No pericardial commitment was found. Due to refractory congestive heart failure he was listed and successfully transplanted at the age 14. The analysis of the explanted heart revealed diffuse myocite disarray, with no septal asymmetry or subaortic obstruction. He is currently in clinical follow up for 5 years. Case 2) A 10 year-old female with exertion dyspnea, cyanosis and vomits. Due to the family history, she was referred for investigation. Restrictive cardiomyopathy was diagnosed. She was listed for heart transplant and successfully transplanted at the age of 13. The analysis of the explanted heart showed mild thickening of ventricular walls with no asymmetries or subaortic obstruction and several areas of myocyte disarray and fibrosis. She is currently in clinical follow up for 2 years. Blood samples of our patients were tested for mutations in genes MYH7, MYBPC and Troponin I (most frequently related to HCM in Brazil), but no alterations were found. CONCLUSION: HCM is a genetic condition related to mutations in genes that encode components of the sarcomere. It can rarely present with features of restrictive syndrome. Heart transplant is the therapeutic option for refractory congestive heart failure, before the evolution to pulmonary hypertension, with good clinical outcome.
  • article 0 Citação(ões) na Scopus
    Implementation of a High-Risk Outpatient Clinic for Children with Complex Congenital Heart Disease in a Reference Service in Brazil
    (2023) FORONDA, Gustavo; MELO, Vanessa Ferreira Amorim de; GRAU, Claudia Regina Pinheiro de Castro; PIVA, Ingrid Magatti; TAVARES, Glaucia Maria Penha; TANAKA, Ana Cristina Sayuri; MIURA, Nana
    Background: Children with congenital heart disease (CHD), even after surgical approaches, and especially those who undergo staged procedures in the first months of life, remain vulnerable to readmissions and complications, requiring very close monitoring and differentiated intervention strategies. Methods: Descriptive and exploratory study, of the experience report type, which presents the process of building the high -risk outpatient clinic for complex congenital heart diseases (AAR) at the Instituto do Coracao (InCor). Results: Report of the path taken to structure the AAR, demonstrating the organization, interface with the multidisciplinary team, admission and discharge criteria, training, and patient profile. In these five years of care, 275 patients were treated, 59.65% with biventricular interstage physiology, followed by univentricular interstage physiology (34.55%), residual defects after surgical procedures (3.63%), tumors with risk of mechanical obstruction ( 1.45%) and patients with an intrauterine approach (0.72%). The significant number of critical patients who were successfully discharged from hospital (44.72%), the low mortality rate due to sudden deaths at home and the high adherence to follow-up corroborate the impact of this specialized assistance. Conclusions: Despite the limitations of the study, this experience report showed that with few resources, there is the possibility of organizing an AAR with differentiated care, with the objective of early detection and treatment of residual injuries, identification of early interventions, education of parents for follow-up of their children, resulting in individualized treatment, promoting a better quality of life for this population.
  • bookPart
    Aspectos morfológicos e genéticos das cardiopatias e prevenção cardiovascular na infância e adolescência
    (2016) PEREIRA, Alexandre da Costa; TANAKA, Ana Cristina Sayuri; BERTOLA, Débora Romeo; JATENE, Ieda Biscegli; MIURA, Nana; AIELLO, Vera Demarchi