Post stroke depression: clinics, etiopathogenesis and therapeutics

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art_PEDROSO_Post_stroke_depression_clinics_etiopathogenesis_and_therapeutics_2015.PDF (183.44 KB)
Citações na Scopus
12
Tipo de produção
article
Data de publicação
2015
Editora
UNIV SAO PAULO, INST PSIQUIATRIA
DOI
Indexadores
SciELO
Scopus
Web of Science
Título da Revista
ISSN da Revista
Título do Volume
Autores
PEDROSO, Vinicius Sousa Pietra
SOUZA, Leonardo Cruz de
TEIXEIRA, Antonio Lucio
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
REVISTA DE PSIQUIATRIA CLINICA, v.42, n.1, p.18-24, 2015
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background: Stroke is a major cause of morbidity and mortality worldwide. Neuropsychiatric disorders are often associated with stroke and, among them, depression is the most prevalent. Post-stroke Depression (PSD) is related to disability, failure in returning to work, impairment in interpersonal functioning and mortality. Its etiopathogenesis is still uncertain, as well as its treatment. In Brazil, there are few data on the impact of PSD. Objective: This work is dedicated to conduct a comprehensive review of the concept of PSD, its pathophysiology, morbidity and treatment. Methods: PubMed, Medline and Lilacs searches of relevant terms yielded 3,265 papers in the last 10 years. We selected original studies and reviews that addressed the aspects mentioned above. Results: We present the history of the notion of PSD and describe its epidemiology, looking to highlight Brazilian studies. Diagnostic criteria and clinical presentation were detailed, with emphasis on cognitive aspects. The four main pathophysiological theories proposed to PSD are presented and we discuss the various treatment strategies, involving psychopharmacologic options, brain stimulation techniques and psychotherapy. Discussion: This work provides comprehensive information on PSD, of great utility for clinical practice and research in this topic.
Palavras-chave
Stroke, cerebrovascular diseases, depression, post-stroke depression, vascular depression
URI
https://observatorio.fm.usp.br/handle/OPI/11947
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Coleções
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/27
Artigos e Materiais de Revistas Científicas - ODS/03