Arginine intake is associated with oxidative stress in a general population

Imagem de Miniatura
Arquivos
art_CARVALHO_Arginine_intake_is_associated_with_oxidative_stress_in_2017.PDF (438.21 KB)
Citações na Scopus
11
Tipo de produção
article
Data de publicação
2017
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCIENCE INC
Autores
CARVALHO, Aline Martins de
OLIVEIRA, Antonio Anax Falcao de
LOUREIRO, Ana Paula de Melo
FISBERG, Regina Mara
MARCHIONI, Dirce Maria
Citação
NUTRITION, v.33, p.211-215, 2017
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Objective: The aim of this study was to assess the association between protein and arginine from meat intake and oxidative stress in a general population. Methods: Data came from the Health Survey for Sao Paulo (ISA-Capital), a cross-sectional population based study in Brazil (N = 549 adults). Food intake was estimated by a 24-h dietary recall. Oxidative stress was estimated by malondialdehyde (MDA) concentration in plasma. Analyses were performed using general linear regression models adjusted for some genetic, lifestyle, and biochemical confounders. Results: MDA levels were associated with meat intake (P for linear trend = 0.031), protein from meat (P for linear trend = 0.006), and arginine from meat (P for linear trend = 0.044) after adjustments for confounders: age, sex, body mass index, smoking, physical activity, intake of fruit and vegetables, energy and heterocyclic amines, C-reactive protein levels, and polymorphisms in GSTM1 (glutathione S-transferase Mu 1) and GSTT1 (glutathione S-transferase theta 1) genes. Results were not significant for total protein and protein from vegetable intake (P > 0.05). Conclusions: High protein and arginine from meat intake were associated with oxidative stress independently of genetic, lifestyle, and biochemical confounders in a population-based study. Our results suggested a novel link between high protein/arginine intake and oxidative stress, which is a major cause of age -related diseases.
Palavras-chave
Arginine, Protein, Oxidative stress, General population, Chronic disease
URI
https://observatorio.fm.usp.br/handle/OPI/17909
Referências
  1. Balogh LM, 2011, DRUG METAB REV, V43, P165, DOI 10.3109/03602532.2011.558092
  2. Bastos AS, 2012, ANAL BIOCHEM, V423, P141, DOI 10.1016/j.ab.2012.01.016
  3. Blantz RC, 2000, ACTA PHYSIOL SCAND, V168, P21
  4. Cantwell M, 2004, CANCER EPIDEM BIOMAR, V13, P293, DOI 10.1158/1055-9965.EPI-270-2
  5. Carvalho Aline Martins de, 2016, Br J Nutr, V115, P2011, DOI 10.1017/S0007114516000969
  6. Crabtree MJ, 2011, NITRIC OXIDE-BIOL CH, V25, P81, DOI 10.1016/j.niox.2011.04.004
  7. Ferguson LR, 2010, MEAT SCI, V84, P308, DOI 10.1016/j.meatsci.2009.06.032
  8. Freedman LS, 2011, J NATL CANCER I, V103, P1086, DOI 10.1093/jnci/djr189
  9. Harasym J, 2014, NUTRITION, V30, P511, DOI 10.1016/j.nut.2013.08.019
  10. Jeremy RW, 1996, CIRCULATION, V94, P498
  11. Larsson SC, 2006, INT J CANCER, V119, P2657, DOI 10.1002/ijc.22170
  12. Lorin J, 2014, MOL NUTR FOOD RES, V58, P101, DOI 10.1002/mnfr.201300033
  13. Luiking YC, 2012, AM J PHYSIOL-ENDOC M, V303, pE1177, DOI 10.1152/ajpendo.00284.2012
  14. Luiking YC, 2010, CURR OPIN CLIN NUTR, V13, P97, DOI 10.1097/MCO.0b013e328332f99d
  15. MILLER SA, 1988, NUCLEIC ACIDS RES, V16, P1215, DOI 10.1093/nar/16.3.1215
  16. Moncada S, 2006, BRIT J PHARMACOL, V147, pS193, DOI 10.1038/sj.bjp.0706458
  17. Moncada S, 1993, NEW ENGL J MED, V329, P977
  18. Montonen J, 2013, EUR J NUTR, V52, P337, DOI 10.1007/s00394-012-0340-6
  19. Mori A, 1996, BIOCHEM MOL BIOL INT, V40, P135, DOI 10.1016/0361-9230(96)00044-5
  20. NEPA UNICAMP, 2011, BRAZ TABL FOOD COMP
  21. Santhanam L, 2008, J APPL PHYSIOL, V105, P1632, DOI 10.1152/japplphysiol.90627.2008
  22. Sasso S, 2015, AMINO ACIDS, V47, P1931, DOI 10.1007/s00726-015-1973-6
  23. Satriano J, 2004, AMINO ACIDS, V26, P321, DOI 10.1007/s00726-004-0078-4
  24. Schulman SP, 2006, JAMA-J AM MED ASSOC, V295, P58, DOI 10.1001/jama.295.1.58
  25. Wu GY, 2009, AMINO ACIDS, V37, P1, DOI 10.1007/s00726-009-0269-0
  26. Wu GY, 1998, BIOCHEM J, V336, P1
  27. Wyse ATD, 2001, BRAIN RES, V923, P50
  28. Xia Y, 1996, P NATL ACAD SCI USA, V93, P6770, DOI 10.1073/pnas.93.13.6770
  29. Xia Y, 1997, P NATL ACAD SCI USA, V94, P6954, DOI 10.1073/pnas.94.13.6954
  30. Zell JA, 2007, INT J CANCER, V120, P459, DOI 10.1002/ijc.22311

Coleções
Artigos e Materiais de Revistas Científicas - FM/MLS
Artigos e Materiais de Revistas Científicas - LIM/40