Liver resection and transplantation offer similar 5-year survival for Child-Pugh-Turcotte A HCC-patients with a single nodule up to 5 cm: A multicenter, exploratory analysis

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art_KIKUCHI_Liver_resection_and_transplantation_offer_similar_5_year_2013.PDF (191.74 KB)
Citações na Scopus
28
Tipo de produção
article
Data de publicação
2013
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
ELSEVIER SCI LTD
Autores
SILVA, M. F.
SAPISOCHIN, G.
STRASSER, S. I.
HEWA-GEEGANAGE, S.
CHEN, J.
WIGG, A. J.
JONES, R.
SARAIVA, R.
Citação
EJSO, v.39, n.4, p.386-395, 2013
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Background and aim: The current guideline of the American Association for the Study of Liver Diseases recommends liver resection for Child-Pugh-Turcotte A patients with a single hepatocellular carcinoma, total serum bilirubin <= 1 mg/dL and absence of significant portal hypertension. This subset of patients would have a long-term survival comparable to transplantation. The main aim of this study is to evaluate the survival rates in patients with a single nodule <= 5 cm following resection. Methods: Medical records of 105 Child-Pugh-Turcotte A patients who underwent liver resection between 1997 and 2009 were analyzed in 3 countries. Results: One, 3-, and 5-year survival rate was 97%, 83%, and 66%, respectively, and no variable that can be assessed prior to liver resection predicted survival probabilities. Conclusions: Liver resection offers 5-year survival similar to transplantation for Child-Pugh-Turcotte A patients with hepatocellular carcinoma and a single nodule up to 5 cm, independently of any patient baseline characteristics.
Palavras-chave
Hepatocellular carcinoma, Liver resection, Liver transplantation
URI
https://observatorio.fm.usp.br/handle/OPI/1944
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MGT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/07
Artigos e Materiais de Revistas Científicas - ODS/03