Parathyroid gland anatomical distribution and relation to anthropometric and demographic parameters: a cadaveric study
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Citações na Scopus
29
Tipo de produção
article
Data de publicação
2011
Editora
SPRINGER
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Título do Volume
Autores
HOJAIJ, Flavio
VANDERLEI, Felipe
PLOPPER, Caio
OLIVEIRA, Leonardo
MARCHI, Luis
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Citação
ANATOMICAL SCIENCE INTERNATIONAL, v.86, n.4, p.204-212, 2011
Resumo
Parathyroid glands play an important role in controlling calcium levels, which influence muscular contraction and neurotransmission. The number of variants, localization and ectopic positions make these glands tricky during surgical exploration. Detailed anatomical knowledge of these glands is fundamental to avoid postsurgical hypoparathyroidism, such as failures during thyroidectomy and parathyroid procedures. The purposes of this work were to study and report practical knowledge for surgeons in order to localize the glands. Dissections were performed on 56 cadavers. Gland identity was confirmed by histological study. Also, mediastinal tissue and the carotid sheath were treated with Carnoy's solution to identify ectopic glands. The thyroid gland was divided and sliced to identify parathyroid glands in the parenchymal and subcapsular space. Four or more parathyroid glands were found in 89.3% of the studied specimens. Mean gland weight was 33.1 mg, and its mean measurements were 6.7 x 3.9 x 2.0 mm. In more than 90% of the cases there was a correlation with the inferior laryngeal nerve and the parathyroid glands: the upper glands were located in medial positions, and the lower ones were found to be located laterally. In 42.8% of cases at least one ectopic gland was observed. The main ectopic regions were the mediastinum and thymus (19.6%), thyroid subcapsular space (12.5%) and thyroid parenchyma (5.4%). Quantity, gland characteristics and location were not influenced by anthropometric and demographic parameters. Here we show the high incidence of parathyroid glands positioned at ""abnormal"" locations, and as a controversial topic in endocrine surgery, this matter must be continuously studied and reported in the literature.
Palavras-chave
Parathyroid glands, Anatomical study, Thyroid glands
Referências
- Abboud B, 1996, PRESSE MED, V25, P1156
- ADINOLFI M, 1983, SOUTHERN MED J, V76, P1496
- AKERSTROM G, 1980, AM J PATHOL, V99, P685
- AKERSTROM G, 1981, ACTA PATH MICRO IM A, V89, P367
- AKERSTROM G, 1986, HUM PATHOL, V17, P520, DOI 10.1016/S0046-8177(86)80043-0
- Alveryd A, 1968, Acta Chir Scand, V389, P1
- Lefevre JH, 2007, LANGENBECK ARCH SURG, V392, P685, DOI 10.1007/s00423-007-0201-6
- Mariani G, 2003, J NUCL MED, V44, P1443
- CAKMAKLI S, 1992, INT SURG, V77, P284
- NOBORI M, 1994, SURGERY, V115, P417
- AKERSTROM G, 1984, SURGERY, V95, P14
- Araujo Filho VJ, 2000, REV HOSP CLIN FM SAO, V55, P113
- BLAND KI, 1985, SURG GYNECOL OBSTET, V160, P42
- Carty SE, 1997, SURGERY, V122, P1107, DOI 10.1016/S0039-6060(97)90215-4
- CORDEIRO AC, 1987, THESIS U SAO PAULO S, P57
- Cordeiro A C, 1972, Rev Hosp Clin Fac Med Sao Paulo, V27, P17
- DEVINE RM, 1983, SURGERY, V94, P916
- DUBOST C, 1988, J CHIR-PARIS, V125, P631
- Elgazzar AH, 2001, PATHOPHYSIOLOGIC BASIS OF NUCLEAR MEDICINE, P141
- Ferzli G, 2004, J AM COLL SURGEONS, V198, P349, DOI 10.1016/j.jamcollsurg.2003.10.014
- FREEMAN W., 1934, HUMAN BIOL, V6, P489
- GHANDURMNAYMNEH L, 1986, AM J PATHOL, V125, P292
- Gillot J C, 1995, Ann Otolaryngol Chir Cervicofac, V112, P91
- Gilmour JR, 1937, J PATHOL BACTERIOL, V45, P507, DOI 10.1002/path.1700450304
- Gilmour JR, 1938, J PATHOL BACTERIOL, V46, P133, DOI 10.1002/path.1700460113
- Giordano A, 2003, MED NUCL NELLA PRATI, P171
- Grassetto G, 2008, PET CLIN, V2, P385, DOI 10.1016/J.CPET.2008.04.005
- GUYTON A, 1995, ORMONE PARATIROIDEO, P948
- HALSTED WS, 1907, ANN SURG, V16, P489
- Hooghe L, 1992, Acta Chir Belg, V92, P1
- HUNT PS, 1968, BRIT J SURG, V55, P63, DOI 10.1002/bjs.1800550119
- LEVIN KE, 1989, ARCH SURG-CHICAGO, V124, P911
- LIECHTY RD, 1984, SURGERY, V96, P1099
- MacCallum WG, 1906, BRIT MED J, V1906, P1282
- McHenry C, 1998, AM SURGEON, V64, P678
- MITCHELL BK, 1995, SURG CLIN N AM, V75, P483
- Moore KL, 1999, CLIN ORIENTED ANATOM
- NATHANIELS E K, 1970, Annals of Surgery, V171, P165, DOI 10.1097/00000658-197002000-00001
- RAISZ LG, 1979, ANN INTERN MED, V91, P739
- RANDOLPH GW, 2003, SURG THYROID PARATHY, P507
- ROSLYN JJ, 1983, AM SURGEON, V49, P523
- RUSSELL CF, 1981, ANN SURG, V193, P805, DOI 10.1097/00000658-198106000-00016
- SEDGWICK CE, 1980, SURG THYROID PARATHY, P6
- Shaha AR, 2008, OTOLARYNG CLIN N AM, V41, P1169, DOI 10.1016/j.otc.2008.05.002
- WAGNER PK, 1987, CHIRURG, V58, P543
- Wilson DB, 1998, AM SURGEON, V64, P674