Current pharmacological approaches and perspectives in the treatment of geriatric mood disorders

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Citações na Scopus
7
Tipo de produção
article
Data de publicação
2011
Título da Revista
ISSN da Revista
Título do Volume
Editora
LIPPINCOTT WILLIAMS & WILKINS
Citação
CURRENT OPINION IN PSYCHIATRY, v.24, n.6, p.473-477, 2011
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Purpose of review This work aims to review the most recent developments in the treatment of mood disorders (major depression and bipolar disorder) in the elderly. Recent findings In the last years, few new pharmacological interventions for mood disorders have been developed. Recent studies seek to provide alternative treatment strategies to achieve higher remission rates, including the association of antidepressants, mood stabilizers and psychotherapy and the treatment of specific clusters of symptoms, such as the adjunctive treatment of cognitive impairment with cholinesterase inhibitors. Also, recent studies have been assessing the potential of pharmacogenetic information in the prediction of treatment outcomes. Summary These factors altogether are expected to help the development of personalized treatment strategies that may improve outcomes with fewer adverse effects.
Palavras-chave
antidepressants, bipolar disorder, major depression, mood disorders, mood stabilizers, treatment
Referências
  1. Baldwin R, 2004, PSYCHOL MED, V34, P125, DOI 10.1017/S0033291703008870
  2. Costa E, 2007, AM J GERIAT PSYCHIAT, V15, P17, DOI 10.1097/01.JGP.0000230659.72417.a0
  3. Kessing LV, 2010, BIPOLAR DISORD, V12, P87, DOI 10.1111/j.1399-5618.2009.00788.x
  4. Azar AR, 2011, INT J GERIATR PSYCH, V26, P48, DOI 10.1002/gps.2485
  5. Dombrovski AY, 2007, J AFFECT DISORDERS, V103, P77, DOI 10.1016/j.jad.2007.01.020
  6. Culang ME, 2009, AM J GERIAT PSYCHIAT, V17, P881, DOI 10.1097/JGP.0b013e3181b4bf4a
  7. Bell-McGinty S, 2002, AM J PSYCHIAT, V159, P1424, DOI 10.1176/appi.ajp.159.8.1424
  8. Andreescu C, 2011, PSYCHIAT CLIN N AM, V34, P335, DOI 10.1016/j.psc.2011.02.005
  9. Charney DS, 2003, ARCH GEN PSYCHIAT, V60, P664, DOI 10.1001/archpsyc.60.7.664
  10. Alexopoulos GS, 2010, J AFFECT DISORDERS, V125, P262, DOI 10.1016/j.jad.2010.02.115
  11. Grabovich A, 2010, AM J GERIAT PSYCHIAT, V18, P227, DOI 10.1097/JGP.0b013e3181cb87d6
  12. Butters MA, 2004, ARCH GEN PSYCHIAT, V61, P587, DOI 10.1001/archpsyc.61.6.587
  13. Roose SP, 2005, J CLIN PSYCHOPHARM, V25, pS1, DOI 10.1097/01.jcp.0000162807.84570.6b
  14. Young RC, 2010, BIPOLAR DISORD, V12, P56, DOI 10.1111/j.1399-5618.2009.00779.x
  15. Pelton GH, 2008, INT J GERIATR PSYCH, V23, P670, DOI 10.1002/gps.1958
  16. Lam RW, 2009, J AFFECT DISORDERS, V117, pS26, DOI 10.1016/j.jad.2009.06.041
  17. Reynolds CF, 2011, ARCH GEN PSYCHIAT, V68, P51, DOI 10.1001/archgenpsychiatry.2010.184
  18. Lavsa SM, 2010, AM J HEALTH-SYST PH, V67, P1274, DOI 10.2146/ajhp090611
  19. Yatham LN, 2009, BIPOLAR DISORD, V11, P225, DOI 10.1111/j.1399-5618.2009.00672.x
  20. Alexopoulos GS, 2009, J AFFECT DISORDERS, V119, P132, DOI 10.1016/j.jad.2009.03.004
  21. Moller HJ, 2010, PHARMACOPSYCHIATRY, V43, P210, DOI 10.1055/s-0030-1254152
  22. Blay SL, 2007, AM J GERIAT PSYCHIAT, V15, P790, DOI 10.1097/JGP.0b013e3180654179
  23. Pinquart M, 2006, AM J PSYCHIAT, V163, P1493, DOI 10.1176/appi.ajp.163.9.1493
  24. Mottillo S, 2010, J AM COLL CARDIOL, V56, P1113, DOI 10.1016/j.jacc.2010.05.034
  25. Shores MM, 2009, J CLIN PSYCHIAT, V70, P1009
  26. Mezuk B, 2010, AM J GERIAT PSYCHIAT, V18, P245, DOI 10.1097/JGP.0b013e3181bf9ebd
  27. Meyers BS, 2009, ARCH GEN PSYCHIAT, V66, P838, DOI 10.1001/archgenpsychiatry.2009.79
  28. Forlenza OV, 2011, BRIT J PSYCHIAT, V198, P351, DOI 10.1192/bjp.bp.110.080044
  29. Reynolds CF, 2010, INT J GERIATR PSYCH, V25, P1134, DOI 10.1002/gps.2443
  30. Conradi HJ, 2011, PSYCHOL MED, V41, P1165, DOI 10.1017/S0033291710001911
  31. Lavretsky H, 2005, J CLIN PSYCHIAT, V66, P964
  32. Butters MA, 2000, AM J PSYCHIAT, V157, P1949, DOI 10.1176/appi.ajp.157.12.1949
  33. Sneed JR, 2010, AM J GERIAT PSYCHIAT, V18, P128, DOI 10.1097/JGP.0b013e3181c796d2
  34. McIntyre RS, 2010, J AFFECT DISORDERS, V126, P366, DOI 10.1016/j.jad.2010.04.012
  35. Schouws SNTM, 2010, J AFFECT DISORDERS, V125, P330, DOI 10.1016/j.jad.2009.12.004
  36. Aziz Rehan, 2006, Am J Geriatr Pharmacother, V4, P347, DOI 10.1016/j.amjopharm.2006.12.007
  37. Balanza-Martinez V, 2010, EUR J PHARMACOL, V626, P87, DOI 10.1016/j.ejphar.2009.10.018
  38. Copeland John R M, 2004, World Psychiatry, V3, P45
  39. Drago Antonio, 2009, Human Genomics, V3, P257
  40. Forlenza OV, 2001, INT PSYCHOGERIATR, V13, P75, DOI 10.1017/S1041610201007475
  41. Ihara K, 1998, Environ Health Prev Med, V3, P44, DOI 10.1007/BF02931238
  42. Jarman CN, 2010, J ALTERN COMPLEM MED, V16, P251, DOI 10.1089/acm.2009.0325
  43. Rondanelli M, 2010, J AM COLL NUTR, V29, P55
  44. Sajatovic M, 2011, PSYCHIAT CLIN N AM, V34, P319, DOI 10.1016/j.psc.2011.02.007
  45. Sousa R. T., 2011, NEUROSCI LETT, V494, P54
  46. Vasudev K, 2010, J CLIN PSYCHOPHARM, V30, P282, DOI 10.1097/JCP.0b013e3181db2684