Associations between symptoms of depression and heart rate variability: An exploratory study

Imagem de Miniatura
Arquivos
art_BORRIONE_Associations_between_symptoms_of_depression_and_heart_rate_2018.PDF (374.64 KB)
Citações na Scopus
22
Tipo de produção
article
Data de publicação
2018
Editora
ELSEVIER IRELAND LTD
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
PSYCHIATRY RESEARCH, v.262, p.482-487, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Major depressive disorder (MDD) is associated with decreased heart rate variability (HRV), a predictor of cardiovascular morbidity by many, but not all studies. This inconsistency could be due to the association of HRV with specific depressive symptoms. Here, we investigated the association of HRV parameters with components of depressive symptoms from 120 MDD patients, at baseline of a published trial comparing the effect of sertraline to transcranial direct current stimulation. We used Principal Component Analysis to extract components of the Hamilton Rating Scale for Depression (HAM-D-17), the Montgomery Asberg Depression Rating Scale (MADRS) and the Beck Inventory for Depressive Symptomatology (BDI). We constructed one equation of multiple linear regression for each HRV parameter as the dependent variable, and the components of depressive symptoms of the three scales as the independent ones, adjusted for age and gender. A component of HAM-D-17 predicted LF/HF (low frequency/high frequency) and a component of MADRS predicted LF (low frequency). ""Guilt"" and ""loss of interest/pleasure in activities"" were present in the components of both scales, and the MADRS component also included ""psychomotor retardation"". These results suggest that melancholic features might be relevant for the association between MDD and HRV. Considering multiple comparisons, these results are preliminary.
Palavras-chave
Depressive symptoms, Major depressive disorder, Heart rate, Melancholic features, Melancholia, Cardiovascular disease
URI
https://observatorio.fm.usp.br/handle/OPI/26831
Referências
  1. Aberg MAI, 2014, PSYCHOL MED, V44, P779, DOI 10.1017/S0033291713001207
  2. ABLONSKYTEDUDONIEN, 2013, MED LITH, V49, P262
  3. Bassett D, 2016, AUST NZ J PSYCHIAT, V50, P511, DOI 10.1177/0004867415622689
  4. BECK AT, 1961, ARCH GEN PSYCHIAT, V4, P561
  5. Billman GE, 2013, FRONT PHYSIOL, V4, DOI 10.3389/fphys.2013.00026
  6. Brunoni AR, 2013, JAMA PSYCHIAT, V70, P383, DOI 10.1001/2013.jamapsychiatry.32
  7. Brunoni AR, 2013, INT J NEUROPSYCHOPH, V16, P1937, DOI 10.1017/S1461145713000497
  8. Camm AJ, 1996, EUR HEART J, V17, P354
  9. CARNEY RM, 1995, AM J CARDIOL, V76, P562, DOI 10.1016/S0002-9149(99)80155-6
  10. Davydov DM, 2007, PROG NEURO-PSYCHOPH, V31, P164, DOI 10.1016/j.pnpbp.2006.08.015
  11. De Jonge P, 2007, PSYCHOSOM MED, V69, P735, DOI 10.1097/PSY.0b013e31815743ca
  12. Dinleyici EC, 2013, CARDIOL RES PRACT, DOI 10.1155/2013/196506
  13. Fourie MM, 2011, PSYCHOPHYSIOLOGY, V48, P888, DOI 10.1111/j.1469-8986.2010.01157.x
  14. Goldstein DS, 2011, EXP PHYSIOL, V96, P1255, DOI 10.1113/expphysiol.2010.056259
  15. HAMILTON M, 1960, J NEUROL NEUROSUR PS, V23, P56, DOI 10.1136/jnnp.23.1.56
  16. Hillebrand S, 2013, EUROPACE, V15, P742, DOI 10.1093/europace/eus341
  17. Hutmacher MM, 2015, BRIT J CLIN PHARMACO, V79, P132, DOI 10.1111/bcp.12451
  18. Jandackova VK, 2016, PSYCHOL MED, V46, P2121, DOI 10.1017/S003329171600060X
  19. Kemp AH, 2015, FRONT PSYCHOL, V6, DOI 10.3389/fpsyg.2015.00187
  20. Kemp AH, 2014, AM J PSYCHIAT, V171, P1328, DOI 10.1176/appi.ajp.2014.13121605
  21. Kemp AH, 2014, FRONT PSYCHOL, V5, DOI 10.3389/fpsyg.2014.01387
  22. Kemp AH, 2014, PSYCHOPHARMACOLOGY, V231, P2281, DOI 10.1007/s00213-013-3374-4
  23. Kemp AH, 2013, INT J PSYCHOPHYSIOL, V89, P288, DOI 10.1016/j.ijpsycho.2013.06.018
  24. Kemp AH, 2012, PLOS ONE, V7, DOI 10.1371/journal.pone.0030777
  25. Kemp AH, 2010, BIOL PSYCHIAT, V67, P1067, DOI [10.1016/j.biopsych.2009.12.012, 10.1016/j.biopsych.2009.11.019]
  26. Lemogne C, 2011, PSYCHOSOM MED, V73, P731, DOI 10.1097/PSY.0b013e3182365dc7
  27. Leroy M, 2010, COMPR PSYCHIAT, V51, P8, DOI 10.1016/j.comppsych.2009.01.011
  28. Licht CMM, 2008, ARCH GEN PSYCHIAT, V65, P1358, DOI 10.1001/archpsyc.65.12.1358
  29. Lichtman JH, 2014, CIRCULATION, V129, P1350, DOI 10.1161/CIR.0000000000000019
  30. MONTGOMERY SA, 1979, BRIT J PSYCHIAT, V134, P382, DOI 10.1192/bjp.134.4.382
  31. Moser M, 1998, J AFFECT DISORDERS, V48, P115, DOI 10.1016/S0165-0327(97)00164-X
  32. O'Regan C, 2015, PSYCHOL MED, V45, P623, DOI 10.1017/S0033291714001767
  33. Parker G, 2010, AM J PSYCHIAT, V167, P745, DOI 10.1176/appi.ajp.2010.09101525
  34. Pearson RM, 2012, ARCH WOMEN MENT HLTH, V15, P95, DOI 10.1007/s00737-012-0269-z
  35. del Paso GAR, 2013, PSYCHOPHYSIOLOGY, V50, P477, DOI 10.1111/psyp.12027
  36. Rottenberg J, 2007, J AFFECT DISORDERS, V103, P173, DOI 10.1016/j.jad.2007.01.028
  37. Rottenberg J, 2002, EMOTION, V2, P135, DOI 10.1037//1528-3542.2.2.135
  38. Stein PK, 2000, J PSYCHOSOM RES, V48, P493, DOI 10.1016/S0022-3999(99)00085-9
  39. Verhoeven F. E., 2011, DEPRESS RES TREAT, V2011
  40. Virtanen R, 2003, PSYCHOSOM MED, V65, P751, DOI 10.1097/01.PSY.0000088760.65046.CF
  41. Wang YM, 2013, BMC PSYCHIATRY, V13, DOI 10.1186/1471-244X-13-187
  42. Watanabe S, 2013, CIRC J, V77, P1018, DOI 10.1253/circj.CJ-12-1043
  43. Wilson ST, 2016, PSYCHIAT RES, V240, P241, DOI 10.1016/j.psychres.2016.04.033
  44. Yang AC, 2011, J AFFECT DISORDERS, V131, P179, DOI 10.1016/j.jad.2010.11.030
  45. Yeh TC, 2016, PROG NEURO-PSYCHOPH, V64, P60, DOI 10.1016/j.pnpbp.2015.07.007

Coleções
Artigos e Materiais de Revistas Científicas - FM/MCM
Artigos e Materiais de Revistas Científicas - FM/MPS
Artigos e Materiais de Revistas Científicas - HC/IPq
Artigos e Materiais de Revistas Científicas - LIM/20
Artigos e Materiais de Revistas Científicas - LIM/21
Artigos e Materiais de Revistas Científicas - LIM/27
Carregar mais