Bipolar spectrum in major depressive disorders

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art_ANGST_Bipolar_spectrum_in_major_depressive_disorders_2018.PDF.pdf (732.15 KB)
Citações na Scopus
24
Tipo de produção
article
Data de publicação
2018
Editora
SPRINGER HEIDELBERG
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
ANGST, J.
MERIKANGAS, K. R.
CUI, L.
METER, A. Van
AJDACIC-GROSS, V.
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, v.268, n.8, p.741-748, 2018
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Growing evidence for the spectrum concept of most mental disorders, particularly mood disorders, has challenged the arbitrary distinctions inherent in the contemporary categorical diagnostic classification system. Detection of manic symptoms in the context of episodes of depression is particularly important because of the implications for differential treatment of bipolar vs unipolar depression. The purpose of this study is to characterize the magnitude and clinical correlates of subthreshold manic syndromes or symptoms among people with major depressive disorder (MDD) compared to those without a history of manic symptoms. We defined two subthreshold manifestations-manic syndrome or symptoms-that did not include a criterion for duration. In the context of MDD, we found that the clinical correlates of those with the subthreshold manic syndrome were more similar to those with bipolar-II disorder than to MDD alone, whereas those with manic symptoms only were intermediate between those with subthreshold manic syndrome and MDD alone. These results confirm the spectrum concept of mania and suggest that a manic syndrome should be considered when evaluating people with MDD.
Palavras-chave
Epidemiology, Major depression, Mania, Hypomania, Bipolar spectrum
URI
https://observatorio.fm.usp.br/handle/OPI/30296
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Coleções
Artigos e Materiais de Revistas Científicas - LIM/27