Detection and Characterization of Enterovirus B73 from a Child in Brazil
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Citações na Scopus
12
Tipo de produção
article
Data de publicação
2019
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
RIBEIRO, Geovani de Oliveira
LUCHS, Adriana
MILAGRES, Flavio Augusto de Padua
LOBATO, Marcia Cristina Alves Brito Sayao
BRUSTULIN, Rafael
CHAGAS, Rogerio Togisaki das
ABRAO, Maria de Fatima Neves dos Santos
SOARES, Cassia Vitoria de Deus Alves
Citação
VIRUSES-BASEL, v.11, n.1, article ID 16, 7p, 2019
Resumo
Enterovirus B73 is a new member of the Enterovirus B species. First detected in the USA, it has been subsequently identified in China, India, Oman, and the Netherlands. In this study, we characterize the first B73 strain (named TO-127) to be detected in South America. TO-127 was obtained from a child with acute gastroenteritis living in a rural area in Northern Brazil. The subject was not infected with any known enteric pathogens such as norovirus, rotavirus, helminths, or enteric bacteria. Analysis of the nearly full-length TO-127 genome (6993 nt) indicated a 74-75% nucleotide similarity with EV-B73 strains from other countries. Evolutionary analysis suggests that B73 is endemic and widespread.
Palavras-chave
enterovirus B73, virome, picornavirus, pediatric virology, gastroenteritis, phylogenetics
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