LIM/07 - Laboratório de Gastroenterologia Clínica e Experimental

LIM/07 - Laboratório de Gastroenterologia Clínica e Experimental

 

O Laboratório de Gastroenterologia e Clínica Experimental é ligado ao Departamento de Gastroenterologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: doenças inflamatórias, autoimunes e funcionais do intestino: genética, etiopatogenia, imunologia e epidemiologia, doença celíaca: imunologia e epidemiologia; quantificação do glúten em alimentos; nano partículas e micropartículas em processo inflamatório intestinal; modelos experimentais de colite; hepatites virais, cirroses e suas complicações e hepatopatias; doença hepática gordurosa; obesidade; estresse oxidativo e síndrome metabólica.

Site oficial: http://www.limhc.fm.usp.br/portal/lim07-laboratorio-de-gastroenterologia-clinica-e-experimental/

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Recent Submissions

  • TAVARES, Rita Chelly Felix; FELDNER, Ana Cristina de Castro Amaral; PINHO, Joao Renato Rebello; MALTA, Fernanda de Mello; CARVALHO-FILHO, Roberto Jose; SANTANA, Rtibia Anita Ferraz; CASTRO, Vanessa Fusco Duarte de; DASTOLI, Gregorio Tadeu Fernando; LIMA, Juliana Custadio; FERRA, Maria Lucia Cardoso Gomes (DOVE MEDICAL PRESS LTD, ALBANY, NEW ZEALAND, 2018)
    Background: Direct-acting antiviral agents (DAAs) permit the use of interferon (IFN)-free regimens to treat hepatitis C (HCV) in patients with chronic kidney disease (CKD) on hemodialysis (HD) or renal transplant (RTx) ...
  • LEATHERS, James S.; BALDERRAMO, Domingo; PRIETO, Jhon; DIEHL, Fernando; GONZALEZ-BALLERGA, Esteban; FERREIRO, Melina R.; CARRERA, Enrique; BARREYRO, Fernando; DIAZ-FERRER, Javier; SINGH, Dupinder; MATTOS, Angelo Z.; CARRILHO, Flair; DEBES, Jose D. (KOWSAR PUBL, HOENSBROEK, NETHERLANDS, 2018)
  • FONSECA, Leonardo Gomes da; MARTA, Guilherme Nader; BRAGHIROLI, Maria Ignez Freitas Melro; CHAGAS, Aline Lopes; CARRILHO, Flair Jose; HOFF, Paulo Marcelo; SABBAGA, Jorge (BMC, LONDON, ENGLAND, 2018)
    BackgroundBefore the targeted therapies era, cytotoxic chemotherapy (CCT) was an option for advanced hepatocellular carcinoma (HCC), even with the lack of supporting evidence. Since the last decade, sorafenib has been ...
  • TODA, Karla Sawada; KIKUCHI, Luciana; CHAGAS, Aline Lopes; TANIGAWA, Ryan Yukimatsu; PARANAGUA-VEZOZZO, Denise Cerqueira; PFIFFER, Tulio; ROCHA, Manoel de Souza; ALVES, Venancio Avancini Ferreira; CARRILHO, Flair Jose (XIA & HE PUBLISHING INC, SUGAR LAND, USA, 2015)
    Background and Aims: Schistosomiasis is a major chronic disease of humans in endemic regions, and infected individuals may develop a spectrumof pathology, including hepatic fibrosis, hepatosplenomegaly, and portal hypertension. ...
  • HORVAT, Natally; ROCHA, Manoel Souza; CHAGAS, Aline Lopes; OLIVEIRA, Brunna Clemente; PACHECO, Mariana Poltronieri; BINOTTO, Maria Angelica; IKARI, Nana Miura; PARANAGUA-VEZOZZO, Denise Cerqueira; LEAO-FILHO, Hilton Muniz; VICENTINI, Joao Rafael Terneira; SILVA FILHO, Mauricio Ricardo Moreira da; JATENE, Marcelo Biscegli; CARRILHO, Flair Jose; CERRI, Giovanni Guido (AMER ROENTGEN RAY SOC, RESTON, USA, 2018)
    OBJECTIVE. Currently, there is no consensus in the literature regarding the screening of hepatic nodules in patients who have undergone the Fontan procedure. The objectives of this study are to evaluate in this population ...
  • ANDRADE, Adriana R.; BARROS, Luisa L.; AZEVEDO, Matheus F. C.; CARLOS, Alexandre S.; DAMIAO, Aderson O. M. C.; SIPAHI, Aytan M.; LEITE, Andre Z. A. (NATURE PUBLISHING GROUP, NEW YORK, USA, 2018)
    Objectives: Patients with inflammatory bowel disease have a higher risk of thrombosis, which is associated with a higher morbidity and mortality. Most data about VTE are related to hospitalized patients with active disease, ...
  • MOREIRA, Regina Celia; SANTOS, Ana Paula de Torres; LISBOA-NETO, Gaspar; MENDES-CORREA, Maria Cassia Jacintho; LEMOS, Marcilio Figueiredo; MALTA, Fernanda Mello; SANTANA, RAbia Anita Ferraz; DASTOLI, Gregorio Tadeu Fernando; CASTRO, Vanessa Fusco Duarte de; PINHO, Joao Renato Rebello (SPRINGER WIEN, WIEN, AUSTRIA, 2018)
    Hepatitis C (HCV)-infected patients are treated with direct-acting antiviral agents (DAAs) in highly effective, well-tolerated, all-oral regimens. However, naturally occurring resistance-associated amino acid substitutions ...
  • MAZO, Daniel Ferraz de Campos; MATTAR, Rejane; STEFANO, Jose Tadeu; SILVA-ETTO, Joyce Matie Kinoshita da; DINIZ, Marcio Augusto; DUARTE, Sebastiao Mauro Bezerra; RABELO, Fabiola; LIMA, Rodrigo Vieira Costa; CAMPOS, Priscila Brizolla de; CARRILHO, Flair Jose; OLIVEIRA, Claudia P. (BAISHIDENG PUBLISHING GROUP INC, PLEASANTON, USA, 2016)
    AIM To assess lactase gene (LCT)-13910C>T polymorphisms in Brazilian non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) patients in comparison with healthy controls. METHODS This was a ...
  • CAVALCANTE, Lourianne Nascimento; STEFANO, Jose Tadeu; V, Mariana Machado; MAZO, Daniel F.; RABELO, Fabiola; SANDES, Kiyoko Abe; CARRILHO, Flair Jose; CORTEZ-PINTO, Helena; LYRA, Andre Castro; OLIVEIRA, Claudia P. de (BAISHIDENG PUBLISHING GROUP INC, PLEASANTON, USA, 2015)
    AIM: To study the association between genetic ancestry, non-alcoholic fatty liver disease (NAFLD) metabolic characteristics in two cohorts of patients, from Brazil and Portugal. METHODS: We included 131 subjects from Brazil ...
  • OKADA, Livia Samara dos Reis Rodrigues; OLIVEIRA, Claudia P.; STEFANO, Jose Tadeu; NOGUEIRA, Monize Aydar; SILVA, Ismael Dale Cotrim Guerreiro da; CORDEIRO, Fernanda Bertucce; ALVES, Venancio Avancini Ferreira; TORRINHAS, Raquel Susana; CARRILHO, Flair Jose; PURI, Puneet; WAITZBERG, Dan L. (CHURCHILL LIVINGSTONE, EDINBURGH, SCOTLAND, 2018)
    Background & aims: Currently there is no FDA-approved therapy for nonalcoholic steatohepatitis (NASH). Increased n-6/n-3 polyunsaturated fatty acids (PUFA) ratio can induce endoplasmic reticulum (ER) stress and mitochondrial ...
  • RABELO, Fabiola; STEFANO, Jose Tadeu; CAVALEIRO, Ana Mercedes; LIMA, Rodrigo Vieira Costa; MAZO, DanielFerraz de Campos; CARRILHO, Flair Jose; CORREA-GIANNELLA, Maria Lucia; OLIVEIRA, Claudia P. (ELSEVIER SCIENCE BV, AMSTERDAM, NETHERLANDS, 2018)
    Background: Oxidative stress has been implicated in the progression of severe forms of non-alcoholic fatty liver disease (NAFLD). NADPH oxidase produces reactive oxygen species. In the present study, we investigated for ...
  • TANNURI, Ana Cristina Aoun; ROTONDO, Italo Geraldo; BARROS, Guilherme Garcia; VAISBERG, Victor Van; MENDES-NETO, Cicero; PAES, Vitor Ribeiro; COELHO, Maria Cecilia Mendonca; GONCALVES, Josiane; SERAFINI, Suellen; TANNURI, Uenis (HOSPITAL CLINICAS, UNIV SAO PAULO, SAO PAULO, BRAZIL, 2018)
    OBJECTIVES: The purpose of this study was to present an experimental model of short bowel syndrome (SBS) in weaning rats and to compare the adaptative mechanisms of the remaining bowel in weaning rats and adult animals by ...
  • BARROS, Guilherme Garcia; TANNURI, Ana Cristina Aoun; ROTONDO, Italo Gerardo; VAISBERG, Vitor Van; SARMENTO, Leandro Silveira; NETO, Cicero Mendes; SERAFINI, Suellen; GONCALVES, Josiane de Oliveira; COELHO, Maria Cecilia Mendonca; TANNURI, Uenis (SPRINGER, NEW YORK, USA, 2018)
    Purpose To evaluate the role of maintenance of the ileocecal valve (ICV) in intestinal adaptation mechanisms, in a weaning rat experimental model of short bowel. Methods Forty animals were operated on to produce short bowel ...
  • COSTA, Fernando Gomes de Barros; LUGãO, Renata dos Santos; MARZINOTTO, Maira Andrade Nacimbem (Manole, BARUERI, BRAZIL, 2017)
  • CHEN, André Tsin Chih; BARALDI, Helena Espindola (Manole, BARUERI, BRAZIL, 2017)
  • NACIF, L.; PARANAGUA-VEZOZZO, D.; GOMES, C.; REINOSO, G.; MISCHIATTI, M.; ANDRAUS, W.; PINHEIRO, R.; ARANTES, R.; ONO, S.; CARRILHO, F.; D'ALBUQUERQUE, L. Carneiro (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2018)
  • BOSQUI, Larissa R.; MARQUES, Priscilla D.; MELO, Gessica B. de; GONCALVES-PIRES, Maria do Rosario F.; MALTA, Fernanda M.; PAVANELLI, Wander R.; CONCHON-COSTA, Ivete; COSTA-CRUZ, Julia M.; PAULA, Fabiana M.; COSTA, Idessania N. (ADIS INT LTD, NORTHCOTE, NEW ZEALAND, 2018)
    Detection of Strongyloides stercoralis larvae is particularly challenging because only a small number of larvae are released into the feces, regardless of infection stage. Our objective was to apply conventional polymerase ...
  • FARIA, Luciana Costa; TERRABUIO, Debora Raquel Benedita; LEBLEBICIOGLU, Hakan; HUPRIKAR, Shirish (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2018)
    LIM/07
  • PAULA, Fabiana M.; MALTA, Fernanda M.; MARQUES, Priscilla D.; MELO, Gessica B.; CORRAL, Marcelo A.; GOTTARDI, Maiara; PINHO, Joao R. R.; GONCALVES, Elenice M. N.; CASTILHO, Vera L. P.; PIERROTTI, Ligia C.; ABDALA, Edson; COSTA, Silvia F.; CHIEFFI, Pedro P.; GRYSCHEK, Ronaldo C. B. (WILEY, HOBOKEN, USA, 2018)
    Strongyloidiasis can occur without any symptoms or as a potentially fatal hyperinfection or disseminated infection, principally in immunosuppressed patients. Our study aimed to evaluate the application of conventional ...
  • SILVESTRE, Odilson M.; FARIAS, Alberto Q.; RAMOS, Danusa S.; FURTADO, Meive S.; RODRIGUES, Ana C.; XIMENES, Rafael O.; MAZO, Daniel F. de Campos; ZITELLI, Patricia M. Yoshimura; DINIZ, Marcio A.; ANDRADE, Jose L.; STRUNZ, Celia; FRIEDMANN, Antonio A.; LEE, Samuel S.; CARRILHO, Flair J.; D'ALBUQUERQUE, Luiz A. C.; BACAL, Fernando (LIPPINCOTT WILLIAMS & WILKINS, PHILADELPHIA, USA, 2018)
    Background Cirrhotic cardiomyopathy is characterized by an attenuated contractile response to stress. Long-term exposure of beta-adrenergic receptors to persistently high levels of catecholamines has been implicated in its ...

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