LIM/14 - Laboratório de Investigação em Patologia Hepática

LIM/14 - Laboratório de Investigação em Patologia Hepática

 

O Laboratório de Investigação em Patologia Hepática é ligado ao Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: patologia hepática, com ênfase na patogênese da evolução para formas mais graves de cirrose e para carcinoma hepatocelular; caracterização de anticorpos para estudos imuno-histoquímicos com ênfase em neoplasias digestivas, ginecológicas e condições obstétricas, neuropatologia.

Site oficial: http://www.limhc.fm.usp.br/portal/lim14-laboratorio-de-investigacao-em-patologia-hepatica/

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Recent Submissions

  • ALVES, Venancio Avancini Ferreira; RIMOLA, Jordi (THIEME MEDICAL PUBL INC, NEW YORK, USA, 2019)
    Hepatic angiosarcoma and epithelioid hemangioendothelioma (EHE) might be clinically considered a spectrum since, although more frequently presenting indolent behavior, EHE occasionally evolves to high-grade neoplasms. ...
  • POLES, Wagner A.; NISHI, Erika E.; OLIVEIRA, Mariana B. de; EUGENIO, Angela I. P.; ANDRADE, Tathiana A. de; CAMPOS, Antonio Hugo F. M.; CAMPOS JR., Ruy R. de; VASSALLO, Jose; ALVES, Antonio C.; NETO, Cristovam Scapulatempo; PAES, Roberto Antonio Pinto; LANDMAN, Gilles; ZERBINI, Maria Claudia N.; COLLEONI, Gisele W. B. (SPRINGER, NEW YORK, USA, 2019)
    Aging immune deterioration and Epstein-Barr (EBV) intrinsic mechanisms play an essential role in EBV-positive diffuse large B-cell lymphoma (DLBCL) of the elderly (EBV+DLBCLe) pathogenesis, through the expression of viral ...
  • SONG, Alice Tung Wan; ABDALA, Edson; MARTINO, Rodrigo Bronze de; MALBOUISSON, Luis Marcelo Sa; TANIGAWA, Ryan Yukimatsu; ANDRADE, Guilherme Marques; DUCATTI, Liliana; DOI, Andre Mario; PINHO, Joao Renato Rebello; GOMES-GOUVEA, Michele Soares; MALTA, Fernanda de Mello; ARANTES JR., Rubens Macedo; TONACIO, Adriana Coracini; PINTO, Lecio Figueira; HADDAD, Luciana Bertocco Paiva; SANTOS, Vinicius Rocha; PINHEIRO, Rafael Soares Nunes; NACIF, Lucas Souto; GALVAO, Flavio Henrique Ferreira; ALVES, Venancio Avancini Ferreira; ANDRAUS, Wellington; D'ALBUQUERQUE, Luiz Augusto Carneiro (WILEY, HOBOKEN, USA, 2019)
  • RABELO-SANTOS, S. H.; TERMINI, L.; BOCCARDO, E.; DERCHAIN, S.; LONGATTO-FILHO, A.; ANDREOLI, M. A.; COSTA, M. C.; NUNES, R. A. L.; âNGELO-ANDRADE, L. A. L.; VILLA, L. L.; ZEFERINO, L. C. (IMPACT JOURNALS LLC, Brasil, 2018)
    It is well known that persistent infection with high-risk HPV (hr-HPV), mostly HPV-16 and 18, is the main cause of cervical cancer development. Manganese superoxide dismutase (MnSOD or SOD2) are highly expressed in different ...
  • FERNANDES, Locio Flavio Barbour; FREGNANI, Jose Humberto T. G.; STRUNZ, Celia Maria Cassaro; NOGUEIRA, Adriana De Andrade Ramos; LONGATTO-FILHO, Adhemar (SPANDIDOS PUBL LTD, ATHENS, GREECE, 2018)
    The objective of the present study was to evaluate the role of P-selectin in patients with cancer with suspected thromboembolic events (TEEs). Patients with cancer have a four times greater risk of developing TEEs. P-selectin ...
  • PRATI, Bruna; ABJAUDE, Walason da Silva; TERMINI, Lara; MORALE, Mirian; HERBSTER, Suellen; LONGATTO-FILHO, Adhemar; NUNES, Rafaella Almeida Lima; CAMACHO, Lizeth Carolina Cordoba; RABELO-SANTOS, Silvia Helena; ZEFERINO, Luiz Carlos; AGUAYO, Francisco; BOCCARDO, Enrique (NATURE PUBLISHING GROUP, LONDON, ENGLAND, 2019)
    Alterations in specific DNA damage repair mechanisms in the presence of human papillomavirus (HPV) infection have been described in different experimental models. However, the global effect of HPV on the expression of genes ...
  • KORKUT, Anil; ZAIDI, Sobia; KANCHI, Rupa S.; RAO, Shuyun; GOUGH, Nancy R.; SCHULTZ, Andre; LI, Xubin; LORENZI, Philip L.; BERGER, Ashton C.; ROBERTSON, Gordon; KWONG, Lawrence N.; DATTO, Mike; ROSZIK, Jason; LING, Shiyun; RAVIKUMAR, Visweswaran; MANYAM, Ganiraju; RAO, Arvind; SHELLEY, Simon; LIU, Yuexin; JU, Zhenlin; HANSEL, Donna; VELASCO, Guillermo de; PENNATHUR, Arjun; ANDERSEN, Jesper B.; O'ROURKE, Colm J.; OHSHIRO, Kazufumi; JOGUNOORI, Wilma; Bao-Ngoc Nguyen; LI, Shulin; OSMANBEYOGLU, Hatice U.; AJANI, Jaffer A.; MANI, Sendurai A.; HOUSEMAN, Andres; WIZNEROWICZ, Maciej; CHEN, Jian; GU, Shoujun; MA, Wencai; ZHANG, Jiexin; TONG, Pan; CHERNIACK, Andrew D.; DENG, Chuxia; RESAR, Linda; WEINSTEIN, John N.; MISHRA, Lopa; AKBANI, Rehan (CELL PRESS, CAMBRIDGE, USA, 2018)
    We present an integromic analysis of gene alterations that modulate transforming growth factor beta (TGF-beta)Smad-mediated signaling in 9,125 tumor samples across 33 cancer types in The Cancer Genome Atlas (TCGA). Focusing ...
  • MUNARI, Fernanda Franco; CRUVINEL-CARLONI, Adriana; LACERDA, Croider Franco; OLIVEIRA, Antonio Talvane Torres de; SCAPULATEMPO-NETO, Cristovam; SILVA, Sandra Regina Morini da; CREMA, Eduardo; ADAD, Sheila Jorge; RODRIGUES, Maria Aparecida Marchesan; HENRY, Maria Aparecida Coelho Arruda; GUIMARAES, Denise Peixoto; LONGATTO-FILHO, Adhemar; REIS, Rui Manuel (BMC, LONDON, ENGLAND, 2018)
    BackgroundChronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are ...
  • FURUYA, Tatiane K.; JACOB, Carlos E.; TOMITAO, Michele T. P.; CAMACHO, Lizeth C. C.; RAMOS, Marcus F. K. P.; ELUF-NETO, Jose; ALVES, Venancio A. F.; ZILBERSTEIN, Bruno; CECCONELLO, Ivan; RIBEIRO JR., Ulysses; CHAMMAS, Roger (MDPI, BASEL, SWITZERLAND, 2018)
    The chronic inflammatory microenvironment and immune cell dysfunction have been described as critical components for gastric tumor initiation and progression. The diffuse subtype is related to poor clinical outcomes, ...
  • MORON, Roberson A.; JACOB, Carlos Eduardo; BRESCIANI, Claudio Jose Caldas; SIMOES, Kleber; ALVES, Venancio Avancini Ferreira; IRYA, Kyoshi; GAMA-RODRIGUES, Joaquim; CECCONELLO, Ivan; LONGATTO-FILHO, Adhemar; ZILBERSTEIN, Bruno (SPANDIDOS PUBL LTD, ATHENS, GREECE, 2018)
    The aim of the present study was to determine the clinical significance of p53 and p21(ras) p21(wafl), p27(kip1) and p16(ink4a) expression in cases of early gastric cancer. A total of 81 patients who had undergone gastrectomy ...
  • SANTOS, Gabriel Cezar dos; PARRA, Edwin Roger; STEGUN, Felipe Weisshaupt; CIRQUEIRA, Cinthya; DUARTE, Maria Irma; CAPELOZZI, Vera (EUROPEAN RESPIRATORY SOC JOURNALS LTD, SHEFFIELD, ENGLAND, 2012)
  • MALTA, Fernanda; LIMA, Rodrigo V.; SALLES, Ana Paula M.; STEFANO, Jose Tadeu; MAZO, Daniel; ALVES, Venancio A. F.; CARRILHO, Flair Jose; PINHO, Joao Renato R.; OLIVEIRA, Claudia P. M. S. (WILEY, HOBOKEN, USA, 2018)
  • MELARDI, Julia; CUNHA, Diego; FERREIRA, Marianna; BRIGATTI, Nathalia; CARVALHO, Filomena; COMINATO, Louise; STEINMETZ, Leandra; DAMIANI, Durval (KARGER, BASEL, SWITZERLAND, 2018)
  • ZITELLI, Patricia; GOMES-GOUVEA, Michele; MAZO, Daniel; PINHO, Joo Renato R.; ALVES, Venancio A. F.; TANIGAWA, Ryan Yukimatsu; OLIVEIRA, Claudia S.; CARRILHO, Flair Jose; PESSOA, Mario Guimaraes (WILEY, HOBOKEN, USA, 2018)
  • GOMES, Nathalia; SILVA, Thatiana; LERARIO, Antonio; BATISTA, Rafael Loch; FARIA JUNIOR, Jose Antonio; MORAES, Daniela; COSTA, Elaine Maria Frade; NISHI, Mirian; CARVALHO, Luciani Renata; FORCLAZ, Maria Veronica; PAPAZIAN, Regina; MARTINEZ-AGUAYO, Alejandro; PAULA, Leila Pedroso de; CARVALHO, Filomena Marino; VILAIN, Erick; BARSEGHYAN, Hayk Barseghyan; KEEGAN, Catherine; DOMENICE, Sorahia; MENDONCA, Berenice Bilharinho (KARGER, BASEL, SWITZERLAND, 2018)
  • OKADA, Livia Samara Reis Rodrigues; OLIVEIRA, Claudia P. M. S.; STEFANO, Jose Tadeu; NOGUEIRA, Monize Aydar; CORDEIRO, Fernanda Bertucce; ALVES, Venancio A. F.; TORRINHAS, Raquel Suzana; CARRILHO, Flair Jose; WAITZBERG, Dan Linetzky (WILEY, HOBOKEN, USA, 2018)
  • TORRECILLA, Sara; PINYOL, Roser; WEI-QIANG, Leow; WANG, Huan; MOEINI, Agrin; MONTIRONI, Carla; BASSAGANYAS, Laia; ANDREU-OLLER, Carmen; OLIVEIRA, Claudia P. M. S.; ALVES, Venancio A. F.; LACHENMAYER, Anja; ROESSLER, Stephanie; MINGUEZ, Beatriz; SCHIRMACHER, Peter; BOFFETTA, Paolo; DUFOUR, Jean-Francois; THUNG, Swan N.; UZILOV, Andrew; CARRILHO, Flair Jose; CHANG, Charissa Y.; SIA, Daniela; LLOVET, Josep M. (WILEY, HOBOKEN, USA, 2018)
  • SCHAUB, Franz X.; DHANKANI, Varsha; BERGER, Ashton C.; TRIVEDI, Mihir; RICHARDSON, Anne B.; SHAW, Reid; ZHAO, Wei; ZHANG, Xiaoyang; VENTURA, Andrea; LIU, Yuexin; AYER, Donald E.; HURLIN, Peter J.; CHERNIACK, Andrew D.; EISENMAN, Robert N.; BERNARD, Brady; GRANDORI, Carla (CELL PRESS, CAMBRIDGE, USA, 2018)
    Although the MYC oncogene has been implicated in cancer, a systematic assessment of alterations of MYC, related transcription factors, and co-regulatory proteins, forming the proximal MYC network (PMN), across human cancers ...
  • ELLROTT, Kyle; BAILEY, Matthew H.; SAKSENA, Gordon; COVINGTON, Kyle R.; KANDOTH, Cyriac; STEWART, Chip; HESS, Julian; MA, Singer; CHIOTTI, Kami E.; MCLELLAN, Michael; SOFIA, Heidi J.; HUTTER, Carolyn; GETZ, Gad; WHEELER, David; DING, Li (CELL PRESS, CAMBRIDGE, USA, 2018)
    The Cancer Genome Atlas (TCGA) cancer genomics dataset includes over 10,000 tumor-normal exome pairs across 33 different cancer types, in total >400 TB of raw data files requiring analysis. Here we describe the Multi-Center ...
  • RICKETTS, Christopher J.; CUBAS, Aguirre A. de; FAN, Huihui; SMITH, Christof C.; LANG, Martin; REZNIK, Ed; BOWLBY, Reanne; GIBB, Ewan A.; AKBANI, Rehan; BEROUKHIM, Rameen; BOTTARO, Donald P.; CHOUEIRI, Toni K.; GIBBS, Richard A.; GODWIN, Andrew K.; HAAKE, Scott; HAKIMI, A. Ari; HENSKE, Elizabeth P.; HSIEH, James J.; HO, Thai H.; KANCHI, Rupa S.; KRISHNAN, Bhavani; KWAITKOWSKI, David J.; LUI, Wembin; MERINO, Maria J.; MILLS, Gordon B.; MYERS, Jerome; NICKERSON, Michael L.; REUTER, Victor E.; SCHMIDT, Laura S.; SHELLEY, C. Simon; SHEN, Hui; SHUCH, Brian; SIGNORETTI, Sabina; SRINIVASAN, Ramaprasad; TAMBOLI, Pheroze; THOMAS, George; VINCENT, Benjamin G.; VOCKE, Cathy D.; WHEELER, David A.; YANG, Lixing; KIM, William T.; ROBERTSON, A. Gordon; SPELLMAN, Paul T.; RATHMELL, W. Kimryn; LINEHAN, W. Marston (CELL PRESS, CAMBRIDGE, USA, 2018)
    Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three ...

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