LIM/14 - Laboratório de Investigação em Patologia Hepática

O Laboratório de Investigação em Patologia Hepática é ligado ao Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: patologia hepática, com ênfase na patogênese da evolução para formas mais graves de cirrose e para carcinoma hepatocelular; caracterização de anticorpos para estudos imuno-histoquímicos com ênfase em neoplasias digestivas, ginecológicas e condições obstétricas, neuropatologia.

Site oficial: http://limhc.fm.usp.br/portal/lim14-laboratorio-de-investigacao-em-patologia-hepatica/

Browse

Recent Submissions

  1. Management of Early-Stage Cervical Cancer: A Literature Review

    CANCERS, v.14, n.3, article ID 575, 17p, 2022

    Simple Summary Despite being a preventable disease, cervical cancer still causes morbidity and deaths worldwide. In the early stages (FIGO IA1 with lymph-vascular space invasion-IIA1), the disease is highly curable. The primary treatment for early-stage cervical cancer is radical hysterectomy wit...

  2. Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes

    BREAST CANCER RESEARCH AND TREATMENT, v.192, n.1, p.43-52, 2022

    Purpose Breast cancer (BC) is considered a heterogeneous disease composed of distinct subtypes with diverse clinical outcomes. Luminal subtype tumors have the best prognosis, and patients benefit from endocrine therapy. However, resistance to endocrine therapies in BC is an obstacle to successful...

  3. Histopathological factors versus margin size in single colorectal liver metastases: Does a 1-cm margin size matter?

    SCANDINAVIAN JOURNAL OF SURGERY, v.111, n.1, article ID 14574969211069329, 8p, 2022

    Background and objective: The ideal margin width for surgical resection of colorectal liver metastases has been extensively studied, but not sufficiently in accordance with other pathological factors. The aim of this study was to assess for the first time the prognostic impact of margin widths ac...

  4. Prognostic Impact of Pathology, Cytoreduction, and Tumor Markers in Pseudomyxoma Peritonei

    JOURNAL OF SURGICAL RESEARCH, v.274, p.68-76, 2022

    Introduction: The pathologic classification of pseudomyxoma peritonei is controversial. This study aimed to standardize the histopathological evaluation of pseudomyxoma peritonei and identify the clinicopathological factors associated with survival. Methods: A pathologic review was performed to s...

  5. GASTRIC CANCER WITH POSITIVE EXPRESSION OF ESTROGEN RECEPTOR ALPHA: A CASE SERIES FROM A SINGLE WESTERN CENTER

    ABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, v.34, n.4, article ID e1635, 6p, 2021

    BACKGROUND: Despite advances in therapies, the prognosis of patients with advanced gastric cancer (GC) remains poor. Several studies have demonstrated the expression of estrogen receptor alpha (ERa); however, its significance in GC remains controversial. AIM: The present study aims to report a ca...

  6. ASSOCIATION BETWEEN PNPLA3 AND TM6SF2 GENE POLYMORPHISMS AND GENETIC ANCESTRY IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE FROM A HIGHLY ADMIXED BRAZILIAN POPULATION

    HEPATOLOGY, v.74, suppl.1, p.934A-934A, 2021

  7. Extranodal NK/T-cell lymphoma, nasal type with extensive cardiopulmonary involvement

    AUTOPSY AND CASE REPORTS, v.11, article ID e2021246, p, 2021

    Extranodal NK/T-cell lymphoma, nasal type (ENKTL-NT) is a rare type of Non-Hodgkin’s lymphoma, which usually presents with extranodal involvement and affects the nasal/upper aerodigestive tract in the classical presentation. Herein, we report the case of a 31-year-old, previously healthy, male pa...

  8. Profile of esophageal squamous cell carcinoma mutations in Brazilian patients

    SCIENTIFIC REPORTS, v.11, n.1, article ID 20596, 13p, 2021

    Esophageal cancer is an aggressive tumor that has a high rate of incidence and mortality worldwide. It is the 10th most frequent type in Brazil, being squamous cell carcinoma (ESCC) the predominant subtype. There is currently an incessant search to identify the frequently altered genes associated...

  9. A positive HPV test with positive p16/Ki-67 double staining in self-sampled vaginal material is an accurate tool to detect women at risk for cervical cancer

    CANCER CYTOPATHOLOGY, v.130, n.1, p.41-54, 2022

    BACKGROUND: The development of efficient strategies for managing high-risk human papillomavirus (HR-HPV)-positive women is a major challenge when human papillomavirus-based primary screening is being performed. The objectives of this study were to evaluate the comparative effectiveness of HR-HPV ...

  10. Hepatitis E virus infection increases the risk of diabetes and severity of liver disease in patients with chronic hepatitis C virus infection

    CLINICS, v.76, article ID e3270, 6p, 2021

    OBJECTIVES: Co-infection with hepatitis A or B viruses may aggravate liver injury in patients infected with hepatitis C virus (HCV). However, few studies have assessed co-infection with hepatitis E virus (HEV) and HCV. Therefore, this study aimed to assess the prevalence and impact of HEV infecti...