LIM/14 - Laboratório de Investigação em Patologia Hepática

LIM/14 - Laboratório de Investigação em Patologia Hepática

 

O Laboratório de Investigação em Patologia Hepática é ligado ao Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo (FMUSP).

Linhas de pesquisa: patologia hepática, com ênfase na patogênese da evolução para formas mais graves de cirrose e para carcinoma hepatocelular; caracterização de anticorpos para estudos imuno-histoquímicos com ênfase em neoplasias digestivas, ginecológicas e condições obstétricas, neuropatologia.

Site oficial: http://limhc.fm.usp.br/portal/lim14-laboratorio-de-investigacao-em-patologia-hepatica/

Collections in this community

Recent Submissions

  • CASTRO, Joana Vieira de; GONCALVES, Celine S.; MARTINS, Eduarda P.; MIRANDA-LORENZO, Irene; CERQUEIRA, Mariana T.; LONGATTO-FILHO, Adhemar; PINTO, Afonso A.; REIS, Rui L.; SOUSA, Nuno; HEESCHEN, Christopher; COSTA, Bruno M. (MDPI, BASEL, SWITZERLAND, 2021)
    Simple Summary Since glioblastoma stem cells (GSCs) have paramount roles in tumor initiation, progression, recurrence, and therapy resistance, innovative approaches to specifically identify and isolate GSCs in a straightforward ...
  • MATOS, Leandro Luongo; MENDERICO JUNIOR, Gilberto Mendes; THEODORO, Therese Rachell; PASINI, Fatima Solange; ISHIKAWA, Marina de Menezes; RIBEIRO, Andromeda Aryane Bomtempo; MELLO, Evandro Sobroza de; PINHAL, Maria Aparecida da Silva; MOYSES, Raquel Ajub; KULCSAR, Marco Aurelio Vamondes; DEDIVITIS, Rogerio Aparecido; CERNEA, Claudio Roberto; KOWALSKI, Luiz Paulo (ELSEVIER, AMSTERDAM, NETHERLANDS, 2020)
    The objective of the present study was to evaluate the role of microRNA-mediated remodeling of the extracellular matrix in the process of tumor invasion of oral squamous cell carcinoma and to evaluate its relationship with ...
  • RAMOS, Marcus Fernando Kodama Pertille; PEREIRA, Marina Alessandra; CASTRIA, Tiago Biachi de; RIBEIRO, Renan Ribeiro e; CARDILI, Leonardo; MELLO, Evandro Sobroza de; ZILBERSTEIN, Bruno; RIBEIRO-JUNIOR, Ulysses; CECCONELLO, Ivan (SPRINGER, NEW YORK, UNITED STATES, 2020)
    Purpose The importance of targeted therapy and interest in the study of predictive markers in gastric cancer (GC) have increased in recent years with the use of anti-HER2 therapy and immunotherapy with anti-PD1/PD-L1 for ...
  • STEFANO, Jose Tadeu; GUEDES, Laura Vilar; SOUZA, Arthur Alencar Arrais de; VANNI, Denise Siqueira; ALVES, Venancio Avancini Ferreira; CARRILHO, Flair Jose; LARGURA, Alvaro; ARRESE, Marco; OLIVEIRA, Claudia P. (ELSEVIER ESPANA, MADRID, SPAIN, 2021)
    Introduction/aims: Liver fibrosis assessment is a key issue in the evaluation of nonalcoholic fatty liver disease (NAFLD) patients. In the present study, we aimed to validate a noninvasive marker panel to assess significant ...
  • CARVALHO, Jesus Paula; GIGLIO, Auro Del; ACHATZ, Maria Isabel; CARVALHO, Filomena Marino (KARGER, BASEL, SWITZERLAND, 2020)
    Endometrial cancer is the only gynecological cancer that is rising in incidence and associated mortality worldwide. Although most cases are diagnosed as early stage disease, with chances of cure after primary surgical ...
  • LOPES, Daniel Thomas Pereira; GOMES, Samila Marissa Pinheiro; SIQUEIRA, Sheila Aparecida Coelho; FRASSETTO, Fernando Pereira; SAMPAIO, Pedro Henrique Martins Arruda; MORENO, Cristiane Araujo Martins; ROCHA, Maria Sheila Guimaraes; ESTEPHAN, Eduardo Paula (GEORG THIEME VERLAG KG, STUTTGART, GERMANY, 2020)
    Myasthenia gravis and thymoma are often presented in association with similar to 10% of myasthenic cases having concomitant thymoma. Thymic carcinoma is one of the rarest/aggressive human epithelial tumors and has no ...
  • FERRAZ, Maria Lucia; STRAUSS, Edna; PEREZ, Renata Mello; SCHIAVON, Leonardo; ONO, Suzane Kioko; GUIMARAES, Mario Pessoa; FERREIRA, Adalgisa Paiva; NABUCO, Leticia; CARVALHO-FILHO, Roberto; TOVO, Cristiane; SOUTO, Francisco; ABRAO, Paulo; REUTER, Tania; DANTAS, Thor; VIGANI, Aline; PORTA, Gilda; FERREIRA, Marcelo Simao; PARANA, Raymundo; CIMERMAN, Sergio; BITTENCOURT, Paulo Lisboa (ELSEVIER BRAZIL, RIO DE JANEIRO, BRAZIL, 2020)
    Chronic hepatitis B is an important health problem that can progress to cirrhosis and complications such as hepatocellular carcinoma. There is approximately 290 million of people with chronic hepatitis B virus (HBV) infection ...
  • MAK, Milena Perez; PASINI, Fatima Solange; DIAO, Lixia; GARCIA, Fabyane O. Teixeira; TAKAHASHI, Tiago Kenji; NAKAZOTO, Denyei; MARTINS, Renata Eiras; ALMEIDA, Cristiane Maria; KULCSAR, Marco Aurelio Vamondes; LAMOUNIER, Valdelania Aparecida; NUNES, Emily Montosa; SOUZA, Isabela Cristina de; GARCIA, Marcio Ricardo Taveira; AMADIO, Alex Vieira; SIQUEIRA, Sheila Aparecida C.; SNITCOVSKY, Igor Moyses Longo; SICHERO, Laura; WANG, Jing; JR, Gilberto de Castro (CANCER INTELLIGENCE LTD, BRISTOL, ENGLAND, 2020)
    Background: Cisplatin-based chemoradiation (CCRT) offers locally advanced head and neck squamous cell carcinoma (LAHNSCC) patients high local control rate, however, relapses are frequent. Our goal was to evaluate if ...
  • BUSS, Lewis F.; LEVI, Jose E.; LONGATTO-FILHO, Adhemar; COHEN, Diane D.; CURY, Lise; MARTINS, Toni R.; FUZA, Luiz M.; VILLA, Luisa L.; ELUF-NETO, Jose (WILEY, HOBOKEN, USA, 2021)
    Objective To investigate factors associated with colposcopy attendance in HPV-positive women in Sao Paulo, Brazil. Methods We analyzed data from a prospective cohort of women positive for high-risk HPV (hr-HPV) undergoing ...
  • RASSI-CRUZ, Marcela; MARIA, Andrea G.; FAUCZ, Fabio R.; LONDON, Edra; VILELA, Leticia A. P.; SANTANA, Lucas S.; BENEDETTI, Anna Flavia F.; GOLDBAUM, Tatiana S.; TANNO, Fabio Y.; SROUGI, Vitor; CHAMBO, Jose L.; PEREIRA, Maria Adelaide A.; CAVALCANTE, Aline C. B. S.; CARNEVALE, Francisco C.; PILAN, Bruna; BORTOLOTTO, Luiz A.; DRAGER, Luciano F.; LERARIO, Antonio M.; LATRONICO, Ana Claudia; V, Maria Candida B. Fragoso; MENDONCA, Berenice B.; ZERBINI, Maria Claudia N.; STRATAKIS, Constantine A.; ALMEIDA, Madson Q. (BIOSCIENTIFICA LTD, BRISTOL, ENGLAND, 2021)
    Familial primary aldosteronism (PA) is rare and mostly diagnosed in early-onset hypertension (HT). However, 'sporadic' bilateral adrenal hyperplasia (BAH) is the most frequent cause of PA and remains without genetic etiology ...
  • RAMOS, Marcus Fernando Kodama P.; PEREIRA, Marina Alessandra; CASTRIA, Tiago Biachi; RIBEIRO, Renan Ribeiro e; MELLO, Evandro Sobroza; DIAS, Andre Roncon; ZILBERSTEIN, Bruno; RIBEIRO JR., Ulysses; CECCONELLO, Ivan (ELSEVIER SCIENCE INC, NEW YORK, USA, 2020)
  • PEREIRA, Marina A.; RAMOS, Marcus Fernando Kodama P.; RIBEIRO, Renan Ribeiro e; DIAS, Andre R.; RIBEIRO JR., Ulysses; ZILBERSTEIN, Bruno; CECCONELLO, Ivan; MELLO, Evandro Sobroza; CASTRIA, Tiago B. (ELSEVIER SCIENCE INC, NEW YORK, USA, 2020)
  • PIQUE-GILI, Marta; PINYOL, Roser; TORRECILLA, Sara; WANG, Huan; MONTIRONI, Carla; RAMADORI, Pierluigi; WILLOUGHBY, Catherine E.; ANDREU-OLLER, Carmen; TORRES-MARTIN, Miguel; LEOW, Wei-Qiang; MOEINI, Agrin; TAIK, Patricia; GALLOFRE, Judit Peix; OLIVEIRA, Claudia P. M. S.; ALVES, Venancio A. F.; LACHENMAYER, Anja; ROESSLER, Stephanie; MINGUEZ, Beatriz; SCHIRMACHER, Peter; BOFFETTA, Paolo; DUFOUR, Jean-Francois; THUNG, Swan N.; REEVES, Helen; UZILOV, Andrew; CARRILHO, Flair J.; CHANG, Charissa Y.; HEIKENWAELDER, Mathias; SANYAL, Arun J.; FRIEDMAN, Scott L.; SIA, Daniela; LLOVET, Josep M. (WILEY, HOBOKEN, USA, 2020)
  • DIAS, Tauana Christina; LONGATTO-FILHO, Adhemar; CAMPANELLA, Nathalia C. (FUTURE SCI LTD, LONDON, ENGLAND, 2020)
    The biological importance of human papillomavirus (HPV) in the field of medicine - related to cervical carcinogenesis - has been extensively reported in the last decades. For the first time, a direct correlation between ...
  • PEIXOTO, Renata D'Alpino; ROCHA-FILHO, Duilio R.; WESCHENFELDER, Rui F.; REGO, Juliana F. M.; RIECHELMANN, Rachel; COUTINHO, Anelisa K.; FERNANDES, Gustavo S.; JACOME, Alexandre A.; ANDRADE, Aline C.; MURAD, Andre M.; MELLO, Celso A. L.; MIGUEL, Diego S. C. G.; GOMES, Diogo B. D.; RACY, Douglas J.; MORAES, Eduardo D.; AKAISHI, Eduardo H.; CARVALHO, Elisangela S.; MELLO, Evandro S.; MALUF FILHO, Fauze; COIMBRA, Felipe J. F.; CAPARELI, Fernanda C.; ARRUDA, Fernando F.; VIEIRA, Fernando M. A. C.; TAKEDA, Flavio R.; COTTI, Guilherme C. C.; PEREIRA, Guilherme L. S.; PAULO, Gustavo A.; RIBEIRO, Heber S. C.; LOURENCO, Laercio G.; CROSARA, Marcela; TONETO, Marcelo G.; OLIVEIRA, Marcos B.; OLIVEIRA, Maria de Lourdes; BEGNAMI, Maria Dirlei; FORONES, Nora M.; YAGI, Osmar; ASHTON-PROLLA, Patricia; AGUILLAR, Patricia B.; AMARAL, Paulo C. G.; HOFF, Paulo M.; ARAUJO, Raphael L. C.; PAULA FILHO, Raphael P. Di; GANSL, Rene C.; GIL, Roberto A.; PFIFFER, Tulio E. F.; SOUZA, Tulio; JR, Ulysses Ribeiro; JESUS, Victor Hugo F.; JR, Wilson L. Costa; PROLLA, Gabriel (CANCER INTELLIGENCE LTD, BRISTOL, ENGLAND, 2020)
    Gastric cancer is among the ten most common types of cancer worldwide. Most cases and deaths related to the disease occur in developing countries. Local socio-economic, epidemiologic and healthcare particularities led us ...
  • CARVALHO, Joao Paulo Mancusi de; SALIM, Rafael C.; CARVALHO, Filomena Marino; GENTA, Maria Luiza Nogueira Dias; BARACAT, Edmund Chada; CARVALHO, Jesus Paula (BMJ PUBLISHING GROUP, LONDON, ENGLAND, 2020)
    Aims L1 cell adhesion molecule (L1CAM) has been shown to be correlated with tumour progression, attributed to its possible association with epithelial-mesenchymal transition (EMT), characterised by the expression of vimentin ...
  • SANTANA, Nathalie Oliveira; LERARIO, Antonio Marcondes; SCHMERLING, Claudia Kliemann; MARUI, Suemi; ALVES, Venancio Avancini Ferreira; HOFF, Ana O.; KOPP, Peter; DANILOVIC, Debora Lucia Seguro (BIOSCIENTIFICA LTD, BRISTOL, ENGLAND, 2020)
    Objective: Genomic alterations in Hurthle cell carcinomas (HCC) include chromosomal losses, mitochondria! DNA mutations, and changes in the expression profile of the PI3K-AKT-mTOR and Wnt/beta-catenin pathways. This study ...
  • GOUVEIA, Gisele R.; FERREIRA, Suzete C.; SIQUEIRA, Sheila A. C.; LAGE, Luis Alberto de Padua Covas; HALLACK NETO, Abrahao E.; COSTA, Renata de Oliveira; PEREIRA, Juliana (BMC, LONDON, ENGLAND, 2020)
    BackgroundOCT-1 gene is a member of the POU-homeodomain family of transcriptional regulators of B-lymphocyte differentiation by controlling expression of B-cell specific genes. BCL-2 gene is a potent inhibitor of apoptosis ...
  • PEREHUDOFF, Katrina; VERMANDERE, Heleen; WILLIAMS, Alex; BAUTISTA-ARREDONDO, Sergio; PAEPE, Elien De; DIAS, Sonia; GAMA, Ana; KEYGNAERT, Ines; LONGATTO-FILHO, Adhemar; ORTIZ, Jose; PADALKO, Elizaveta; REIS, Rui Manuel; VANDERHEIJDEN, Nathalie; VEGA, Bernardo; VERBERCKMOES, Bo; DEGOMME, Olivier (BMC, LONDON, ENGLAND, 2020)
    Background Cervical cancer claims 311,000 lives annually, and 90% of these deaths occur in low- and middle-income countries. Cervical cancer is a highly preventable and treatable disease, if detected through screening at ...
  • WEIGAND, Isabel; ALTIERI, Barbara; LACOMBE, Amanda M. F.; BASILE, Vittoria; KIRCHER, Stefan; LANDWEHR, Laura-Sophie; SCHREINER, Jochen; ZERBINI, Maria C. N.; RONCHI, Cristina L.; MEGERLE, Felix; BERRUTI, Alfredo; CANU, Letizia; VOLANTE, Marco; PAIVA, Isabel; CASA, Silvia Della; SBIERA, Silviu; FASSNACHT, Martin; V, Maria Candida B. Fragoso; TERZOLO, Massimo; KROISS, Matthias (ENDOCRINE SOC, WASHINGTON, USA, 2020)
    Context: Objective response rate to mitotane in advanced adrenocortical carcinoma (ACC) is approximately 20%, and adverse drug effects are frequent. To date, there is no marker established that predicts treatment response. ...

View more

Search DSpace



Browse

My Account

Discover

Statistics

RSS Feeds