Livros e Capítulos de Livros - LIM/31
URI Permanente para esta coleção
A coleção de Livros e Capítulos de Livros reúne capítulos e resumos de obras produzidas por autores do sistema FMUSP-HC que inclui a Faculdade de Medicina da Universidade de São Paulo (FMUSP), o Hospital das Clínicas da FMUSP e demais institutos associados.
Navegar
Submissões Recentes
- Management of immune-mediated thrombocytopenia(2022) GABE, C.; ARNOLD, D. M.; SMITH, J. W.; WARKENTIN, T. E.Low circulating platelet numbers can be caused by platelet underproduction, sequestration, hemodilution, consumption, or destruction. This chapter explores the problem of immune-mediated thrombocytopenia, including autoimmune conditions, secondary immune conditions, and alloimmune conditions. Platelets are usually quantitated during a complete blood cell count with a particle counter. Various monoclonal antibody-based assays can be used to detect plate let antibodies. The principal mechanism for immune-mediated thrombocytopenia is antibody-mediated destruction of platelets. Drugs can produce several immune-mediated thrombocytopenic disorders. Heparin-induced thrombocytopenia is a clinicopathologic syndrome, that is, the diagnosis is made most reliably on both clinical and serologic grounds. Alloantigens are genetically determined molecular variations of proteins or carbohydrates that can be recognized immunologically by some healthy persons. Platelet transfusion refractoriness, which is failure to achieve the expected platelet increment after two consecutive platelet transfusion episodes, has several explanations. © 2022 John Wiley & Sons Ltd.
bookPart Cricotireoidostomia(2023) SOARES, Arthur de Campos; PEREIRA, Juliana; MAIA, Ian Ward AbdallabookPart Porfirias(2023) MARIANO, Lívia; SUGANUMA, Liliana MitiebookPart Anemias(2023) MARIANO, Lívia; SUGANUMA, Liliana MitiebookPart Princípios de hemoterapia(2023) COLOMBO, Elisabetta Sachsida; DINARDO, Carla LuanabookPart Alterações neoplásicas dos leucócitos(2023) ABDO, André Neder Ramires; LAGE, Luís Alberto de Pádua CovasbookPart Síndromes mieloproliferativas crônicas(2023) BASTOS, Fernanda Queiroz; CARVALHO, Priscila dos Reis; SEGURO, Fernanda SallesbookPart Sepse(2023) FATOBENE, GiancarlobookPart Suporte transfusional em UTI(2023) DINARDO, Carla Luana; ARRAIS, Cyntia AraújobookPart O hemograma(2021) VELLOSO, Elvira D. R. P.; OTSUKA, Liliana Mitie Suganuma; PENTEADO, Rosana M. CosentinobookPart Erros inatos da imunidade(2023) DUARTE, Alberto José da Silva; VASCONCELOS, Dewton de Moraes; SANTOS, Andréia Rangel; SUMITA, Nairo Massakazu; CARNEIRO-SAMPAIO, MagdabookPart Anemias(2023) CELESTE, Daniele Martins; SUGANUMA, Liliana Mitie; GUALANDRO, Sandra Fatima MenosibookPart 0 Citação(ões) na Scopus Nutraceuticals to prevent thrombogenesis and its application to women's health(2013) SUBBIAH, M. T. R.; BYDLOWSKI, S. P.; MASELLI, L.Thrombosis plays an important role in diseases affecting the arterial and venous vascular systems and substantially contributes to morbidity and mortality in Western countries. The etiology of both arterial and venous thrombosis is complex and involves environmental and genetic factors. Atherothrombosis represents an advanced stage of atherosclerosis in which plaque rupture or erosion trigger increased clotting activity, leading to the formation of an arterial thrombus. Platelets play a pivotal role in the development of atherosclerosis. This important contribution of platelets is strengthened by the observed benefits of antiplatelet agents like aspirin and clopidogrel in primary and secondary therapy of atherothrombotic disorders. Advances in human genome project have enabled scientific investigators to identify a number of mutations in genes that increase the risk of thrombosis. These genetic tests are routinely carried out in the laboratory to identify individuals that may have increased risk for thrombosis and they come under the 'thrombophilic panel' of tests. There are some issues unique to women' health that deserves increased attention for the risk of thrombosis. Oral contraceptive use in women is associated with increased risk of deep vein thrombosis and stroke and risk is even greater for those women with prothrombin and factor V Leiden mutations. Similarly, hormone replacement therapy (HRT) in postmenopausal has also indicated the negative effects on the risk of stroke and venous thrombosis. Women's Health Initiative (WHI) trial using estrogen plus progestin reported a doubling of the risk of stroke and venous thrombosis. These observations provide opportunities to develop nutraceuticals to reduce the activity of platelets and the risk of thrombosis. Antioxidants, procyanidins from guarana (paulinnia cupana), polyphenols from grape and other berries, green tea and garlic phytochemicals are being explored to as nutraceuticals to combat thrombosis. Such nutraceuticals may play a preventive role as dietary supplements, especially in women taking oral contraceptives in reproductive years or hormone replacement therapy in menopause. © 2013 by Nova Science Publishers, Inc. All rights reserved.- Purification and characterization of mouse olfactory ensheathing cells and their potential use for therapy in amyotrophic lateral sclerosis (ALS)(2015) ALVES, C. J.; GUIMARãES, A. B.; MAXIMINO, J. R.; BYDLOWSKI, S. P.; CHADI, G.Olfactory ensheathing cells ( OECs ) are a specialized type of glia that supports axonal regeneration of olfactory neurons . OECs derived from olfactory mucosa represent a potential candidate for therapeutic use in neurological disorders, like amyotrophic lateral sclerosis ( ALS ). The protocol described below produces a highly enriched population of proliferating OECs from neonatal mouse olfactory mucosa by means of an anti-Thy 1.2 antibody leading to a specific cytotoxic lysis of contaminating fibroblasts without damaging the OECs. Purified OECs expressing the two main antigenic markers, the S100 and p75 neurotrophin receptors ( p75NTR ), are plated onto laminin-coated coverslips for immunofluorescence characterization, or Petri dishes for expansion and further investigations. © Springer Science+Business Media New York 2015. All rights are reserved.
- Umbilical Cord Blood Transplantation in Children and Adults(2018) SANZ, J.; VEYS, P.; ROCHA, V.
bookPart Imunoterapia: conceito, principais abordagens clínicas, vantagens e desvantagens(2022) ASSIS, Nadine Gimenez de; TESSAROLLO, Nayara Gusmão; BARBUTO, José Alexandre MarzagãobookPart Icterícia(2020) BRANDãO NETO, Rodrigo Antonio; SANTOS, Fabio Pires de Souza; SATOMI, ErikabookPart Icterícia(2021) BRANDãO NETO, Rodrigo Antonio; SANTOS, Fabio Pires de Souza; SATOMI, ErikabookPart Fármacos utilizados no tratamento de anemias(2021) ALVARENGA, Aline Morgan; DINARDO, Carla Luana; SANTOS, Paulo Caleb Júnior de LimabookPart Metabolismo de lípides plasmáticos e exercicio fisico(2019) NUNES, Ana Paula de Oliveira Barbosa; VINAGRE, Carmen Guilherme Christiano de Matos; MARANHãO, Raul Cavalcante
- «
- 1 (current)
- 2
- 3
- »