Head and Neck Mucosal Melanoma: A Review

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Arquivos
art_LOURENCO_Head_and_Neck_Mucosal_Melanoma_A_Review_2014.PDF (1.06 MB)
Citações na Scopus
73
Tipo de produção
article
Data de publicação
2014
Editora
LIPPINCOTT WILLIAMS & WILKINS
DOI
Indexadores
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Autores
LOURENCO, Silvia V.
FERNANDES, Juliana D.
COUTINHO-CAMILLO, Claudia M.
SANGUEZA, Martin
Autor de Grupo de pesquisa
Editores
Coordenadores
Organizadores
Citação
AMERICAN JOURNAL OF DERMATOPATHOLOGY, v.36, n.7, p.578-587, 2014
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Head and neck mucosal melanoma (MM) is an aggressive and rare neoplasm of melanocytic origin. To date, few retrospective series and case reports have been reported on MM. This article reviews the current evidence on head and neck MM and the molecular pathways that mediate the pathogenesis of this disease. Head and neck MM accounts for 0.7%-3.8% of all melanomas and involve (in decreasing order of frequency) the sinonasal cavity, oral cavity, pharynx, larynx, and upper esophagus. Although many studies have examined MM of the head and neck and the underlying molecular pathways, individual genetic and molecular alterations were less investigated. Further studies are needed to complement existing data and to increase our understanding of melanocytes tumorigenesis.
Palavras-chave
head and neck, mucosal, melanoma
URI
https://observatorio.fm.usp.br/handle/OPI/7469
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Coleções
Artigos e Materiais de Revistas Científicas - FM/MDT
Artigos e Materiais de Revistas Científicas - HC/ICHC
Artigos e Materiais de Revistas Científicas - LIM/06
Artigos e Materiais de Revistas Científicas - ODS/03