RENAN GONCALVES LEONEL DA SILVA
Projetos de Pesquisa
Unidades Organizacionais
LIM/39 - Laboratório de Processamento de Dados Biomédicos, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Globalizing the Scientific Bandwagon: Trajectories of Precision Medicine in China and Brazil(2021) AU, Larry; SILVA, Renan Goncalves Leonel daPrecision medicine (PM) is emerging as a scientific bandwagon within the contemporary biomedical sciences in the United States. PM brings together concepts and tools from genomics and bioinformatics to develop better diagnostics and therapies based on individualized information. Developing countries like China and Brazil have also begun pursuing PM projects, motivated by a desire to claim genomic sovereignty over its population. In spite of commonalities, institutional arrangements produced by the history of genomics research in China and Brazil are ushering PM along different trajectories. In the Chinese case, we identify a strong state-backed push for PM combined with a dynamic network of international academic and private actors along the lines of networked technonationalism that has made large-scale, speculative PM projects possible. The Brazilian case is characterized by an institutional void at the federal level in which PM is driven by domestic academic actors in universities in the regional level, resulting in smaller scale, needs-driven PM projects. Through these cases, this paper shows how a scientific bandwagon adapts to national histories and institutions. Through this peripheral translation of the scientific bandwagon, the global infrastructure of biomedical knowledge has the potential to be transformed.
- Science, Technology and Innovation-oriented health centers, a COVID-19 legacy(2021) SILVA, RENAN G.L. DA; NOVAES, HILLEGONDA M.D.; CHAMMAS, ROGER
- University participation in the production of molecular diagnostic tests for the novel coronavirus in Brazil: the response to health challenges(2020) SILVA, Renan Goncalves Leonel da; CHAMMAS, Roger; PLONSKI, Guilherme Ary; GOLDBAUM, Moises; FERREIRA, Luis Carlos de Souza; NOVAES, Hillegonda Maria Dutilh
- What is the position of the international precision medicine community in relation to the challenges raised by the COVID-19 pandemic?(2021) SILVA, Renan Goncalves Leonel da; IRIART, Jorge Alberto BernsteinPrecision medicine can be defined as a movement of transformation of contemporary biomedicine that orients academic research activity, business models, and the development of health products and services designed individually for the user, based on patients' genetic information and other biomedical markers. In recent years, this community has been quite active in the international scientific scenario. However, during the COVID-19 pandemic, it is still not clear which positions or strategies these groups have adopted to respond to the health crisis. This article aims to understand how the international precision medicine community is reacting to the COVID-19 pandemic and the basis for their approaches and potential solutions suggested for mitigation of the negative effects from the increase in SARS-CoV-2 infections. A search was thus conducted in 28 documents from 18 selected sources, analyzing the narratives adopted by precision medicine experts in scientific articles, editorials, commentaries, perspectives, newspaper stories, newsletters and online conferences of the Personalized Medicine Coalition (PMC). The objective was to understand how these groups envisage a new sociotechnical configuration to respond to the pandemic and its effects.
bookPart Melancolia, disfunção e proliferação celular: notas acerca dos paradigmas do conhecimento biomédico sobre câncer(2019) MESSORA, Elder Al Kondari; SILVA, Renan Gonçalves Leonel da- The emergence of Molecular Biology in the State of Sao Paulo, 1952-1970(2018) SILVA, Renan Goncalves Leonel da; COSTA, Maria Conceicao daThe scientific field known as Molecular Biology has been the subject of research by historians of science and sociologists in developed countries. However, little progress has been made about this topic in developing countries such as Brazil - which have traced specific pathways on the subject in their different regional and local contexts. This article addresses the emergence of Molecular Biology in Brazil, highlighting the history of its organization and development in the state of Sao Paulo between 1952 and 1970. The article presents results of documental research and bibliographical review, complemented by the application of ex-ante-fieldwork interviews with members of the scientific community and leaders of the Sao Paulo Research Foundation, FAPESP. It was verified that the promotion of Molecular Biology in regional context was the result of an explicit activity of negotiation and construction of political alliances between the scientific community and FAPESP. Thus, we sought to advance the understanding of how a set of social factors is capable of interfering on organization and development of a scientific field in Brazilian context.
- Interchangeability and substitution of biosimilars: is health technology assessment (HTA) a tool for decision-making?(2019) ASCEF, Bruna de Oliveira; SILVA, Renan Goncalves Leonel da; OLIVEIRA JUNIOR, Haliton Alves de; SOAREZ, Patricia Coelho De