CAROLINE GIL DE GODOY
Projetos de Pesquisa
Unidades Organizacionais
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- PULMONARY REHABILITATION IN INDIVIDUALS POS-ACUTE COVID-19 INFECTION: PRELIMINARY RESULTS(2021) XAVIER, Rafaella; GODOY, Caroline; SILVA, Erika Gouveia E.; IAMONTI, Vinicius; POMPEU, Jose Eduardo; TOUFEN JR., Carlos; CARVALHO, Carlos; CARVALHO, Celso
- Protocol for Functional Assessment of Adults and Older Adults after Hospitalization for COVID-19(2021) GODOY, Caroline Gil de; SILVA, Erika Christina Gouveia e; OLIVEIRA, Danielle Brancolini de; GAMBETA, Amislaine Cristina; SILVA, Elizabeth Mendes da; CAMPOS, Camila Machado de; SCHMITT, Ana Carolina Basso; CARVALHO, Celso R. F.; FU, Carolina; TANAKA, Clarice; NAKAGAWA, Naomi Kondo; TOUFEN JUNIOR, Carlos; CARVALHO, Carlos Roberto Ribeiro de; HILL, Keith; POMPEU, Jose Eduardo
- Risk Factors for the Impairment of Ambulation in Older People Hospitalized with COVID-19: A Retrospective Cohort Study(2023) SILVA, E. C. G. E.; SCHMITT, A. C. B.; GODOY, C. G. de; OLIVEIRA, D. B. de; TANAKA, C.; TOUFEN, C. Jr.; CARVALHO, C. R. R. de; CARVALHO, C. R. F.; FU, C.; HILL, K. D.; POMPEU, J. E.(1) Background: Some older people hospitalized with COVID-19 have experienced reduced ambulation capacity. However, the prevalence of the impairment of ambulation capacity still needs to be established. Objective: To estimate the prevalence of, and identify the risk factors associated with, the impairment of ambulation capacity at the point of hospital discharge for older people with COVID-19. (2) Methods: A retrospective cohort study. Included are those with an age > 60 years, of either sex, hospitalized due to COVID-19. Clinical data was collected from patients’ medical records. Ambulation capacity prior to COVID-19 infection was assessed through the patients’ reports from their relatives. Multiple logistic regressions were performed to identify the risk factors associated with the impairment of ambulation at hospital discharge. (3) Results: Data for 429 older people hospitalized with COVID-19 were randomly collected from the medical records. Among the 56.4% who were discharged, 57.9% had reduced ambulation capacity. Factors associated with reduced ambulation capacity at discharge were a hospital stay longer than 20 days (Odds Ratio (OR): 3.5) and dependent ambulation capacity prior to COVID-19 (Odds Ratio (OR): 11.3). (4) Conclusion: More than half of the older people who survived following hospitalization due to COVID-19 had reduced ambulation capacity at hospital discharge. Impaired ambulation prior to the infection and a longer hospital stay were risks factors for reduced ambulation capacity.
- Functional impact on adults and older people after hospitalization by Covid-19(2023) OCHIAI, Gabriela Sayuri; GODOY, Caroline Gil de; SILVA, Erika Christina Gouveia E; OLIVEIRA, Danielle Brancolini de; SILVA, Elizabeth Mendes da; VIANA, Bianca de Oliveira Candido; SILVA, Juliana Magalhaes da; SOUZA, Roberta Oliveira Bueno de; SANTOS, Michelle Didone dos; CAMPOS, Camila Machado de; SCHMITT, Ana Carolina Basso; CARVALHO, Celso Ricardo Fernandes de; FU, Carolina; TANAKA, Clarice; TOUFEN JR., Carlos; CARVALHO, Carlos Roberto Ribeiro de; POMPEU, Jose EduardoBackground and Objectives Hospitalization by Covid-19 can cause persistent functional consequences after hospital discharge due to direct and indirect effects of SARS-COV-2 in several organs and systems of the body added to post-intensive care syndrome and prolonged bed rest. These impacts can lead to dependency in activities of daily living, mainly in older people due to aging process and functional decline. This study aimed to compare the effects of hospitalization by Covid-19 on functional capacity of adults and older people and to identify its associated factors. Methods Cross-sectional observational study of 159 survivors of hospitalization by Covid-19 after 1 month from discharge at Hospital das Clinicas of the University of Sao Paulo, divided into groups: adults (aged < 60 years) and older people (aged >= 60 years). Those who did not accept to participate, without availability or without ability to understand the questionnaires were excluded. Functional capacity was assessed by the Barthel Index and patients were classified according to their scores. Data analysis was performed in JASP Statistics program and the sample was compared between the age groups. Wilcoxon test was applied to compare before and after periods, Mann-Whitney test was used for between groups comparison. We adopted alpha = 0.05. Results The total Barthel Index median score was lower 1 month after hospital discharge than in the pre-Covid-19 period. Older people had worse functional status than adults before and also showed greater impairment after hospital discharge. Both groups showed lower Barthel Index classification than before, and older people presented more functional dependence than adults in both periods. Age, sarcopenia and frailty were associated factors. Discussion Hospitalization by Covid-19 impacts functional capacity after 1 month from discharge, especially in older people. Age, sarcopenia and frailty are associated factors. These results suggest need for care and rehabilitation of Covid-19 survivors.
- Association between functionality and respiratory impairment after hospitalization for COVID-19: a cohort study(2021) CARVALHO, Celso Ricardo Fernandes de; GODOY, Caroline Gil; GOUVEIA-SILVA, Erika Christina; XAVIER, Rafaella Fagundes; OLIVEIRA, Danielle Brancolini; CASSIMIRO, Luciana; IAMONTI, Vinicius; TOUFEN JR., Carlos; CARVALHO, Carlos R. R.; POMPEU, Jose Eduardo
- Physical and pulmonary capacities of individuals with severe coronavirus disease after hospital discharge: A preliminary cross-sectional study based on cluster analysis(2021) ALONSO, Angelica Castilho; SILVA-SANTOS, Paulo Roberto; QUINTANA, Marilia Simoes Lopes; SILVA, Vanderlei Carneiro da; BRECH, Guilherme Carlos; BARBOSA, Lorena Goncalves; POMPEU, Jose Eduardo; SILVA, Erika Christina Gouveia e; SILVA, Elizabeth Mendes da; GODOY, Caroline Gil de; GREVE, Julia Maria D'AndreaOBJECTIVE: This study aimed to analyze the physical and pulmonary capacities of hospitalized patients with severe coronavirus disease and its correlation with the time of hospitalization and complications involved. METHODS: A total of 54 patients, aged >= 18 years of both sexes, were evaluated 2-4 months after hospital discharge in Sao Paulo, Brazil. The physical characteristics analyzed were muscle strength, balance, flexibility, and pulmonary function. The K-means cluster algorithm was used to identify patients with similar physical and pulmonary capacities, related to the time of hospitalization. RESULTS: Two clusters were derived using the K-means algorithm. Patients allocated in cluster 1 had fewer days of hospitalization, intensive care, and intubation than those in cluster 2, which reflected a better physical performance, strength, balance, and pulmonary condition, even 2-4 months after discharge. Days of hospitalization were inversely related to muscle strength, physical performance, and lung function: hand grip D (r= -0.28, p=0.04), Short Physical Performance Battery score (r= -0.28, p=0.03), and forced vital capacity (r= -0.29, p=0.03). CONCLUSION: Patients with a longer hospitalization time and complications progressed with greater loss of physical and pulmonary capacities.
- Ambulation capacity, age, immunosuppression, and mechanical ventilation are risk factors of in-hospital death in severe COVID-19: a cohort study(2022) SILVA, Erika Christina Gouveia e; SCHMITT, Ana Carolina Basso; GODOY, Caroline Gil de; GAMBETA, Amislaine Cristina; CARVALHO, Celso Ricardo Fernandes de; FU, Carolina; TANAKA, Clarice; TOUFEN JUNIOR, Carlos; CARVALHO, Carlos Roberto Ribeiro de; POMPEU, Jose EduardoImportance: Despite ambulation capacity being associated with a decreased level of physical activity and survival may be influenced by the functional capacity, studies have not addressed the association between ambulation capacity and death in patients hospitalized by COVID-19. Objective: To verify the functional, clinical, and sociodemographic risk factors associated with in-hospital death in individuals with severe COVID-19. Methods: It is a cohort retrospective study performed at a large tertiary hospital. Patients 18 years of age or more, of both sexes, hospitalized due to severe COVID-19 were included. Cases with dubious medical records and/or missing essential data were excluded. Patients were classified according to their ambulation capacity before the COVID-19 infection. Information regarding sociodemographic characteristics, in-hospital death, total hospital stays, Intensive Care Unit (ICU) stays, and the necessity of Mechanical Ventilation (MV) were collected from medical records and registered in a RedCap database. Multiple logistic regression analysis was used to identify possible factors associated with the in-hospital death rate. Results: Data from 1110 participants were included in the statistical analysis. The median age of the patients was 57 (46-66) years, 58.42% (n = 590) were male, and 61.73% (n = 602) were brown or black. The case fatality rate during hospitalization was 36.0% (n = 363). In-hospital death was associated with ambulation capacity; dependent ambulators (OR = 2.3; CI 95% = 1.2-4.4) and non-functional ambulation (OR = 1.9; CI 95% = 1.1-3.3), age [older adults (OR = 3.0; CI 95% = 1.9-4.), ICU stays (OR = 1.4; CI 95% = 1.2-1.4), immunosuppression (OR = 5.5 CI 95% = 2.3-13.5) and mechanical ventilation (OR = 27.5; CI 95% = 12.0-62.9). Conclusion and relevance: Decreased ambulation capacity, age, length of ICU stay, immunosuppression, and mechanical ventilation was associated with a high risk of in-hospital death due to COVID-19.