Naturally Acquired Humoral Immunity against Malaria Parasites in Non-Human Primates from the Brazilian Amazon, Cerrado and Atlantic Forest

Imagem de Miniatura
Arquivos
art_MONTEIRO_Naturally_Acquired_Humoral_Immunity_against_Malaria_Parasites_in_2020.PDF.pdf (1.7 MB)
Citações na Scopus
12
Tipo de produção
article
Data de publicação
2020
DOI
Scopus
Web of Science
PubMed
Título da Revista
ISSN da Revista
Título do Volume
Editora
MDPI
Autores
FERNANDEZ-BECERRA, Carmen
ARAUJO, Maisa da Silva
MESSIAS, Mariluce Rezende
OZAKI, Luiz Shozo
BUENO, Marina Galvao
CATAO-DIAS, Jose Luiz
CHAGAS, Carolina Romeiro Fernandes
Citação
PATHOGENS, v.9, n.7, article ID 525, 11p, 2020
Projetos de Pesquisa
Unidades Organizacionais
Fascículo
Resumo
Non-human primates (NHPs) have been shown to be infected by parasites of the genusPlasmodium, the etiological agent of malaria in humans, creating potential risks of zoonotic transmission.Plasmodium brasilianum, a parasite species similar toP. malariaeof humans, have been described in NHPs from Central and South America, including Brazil. The merozoite surface protein 1 (MSP1), besides being a malaria vaccine candidate, is highly immunogenic. Due to such properties, we tested this protein for the diagnosis of parasite infection. We used recombinant proteins ofP. malariaeMSP1, as well as ofP. falciparumandP. vivax, for the detection of antibodies anti-MSP1 of these parasite species, in the sera of NHPs collected in different regions of Brazil. About 40% of the NHP sera were confirmed as reactive to the proteins of one or more parasite species. A relatively higher number of reactive sera was found in animals from the Atlantic Forest than those from the Amazon region, possibly reflecting the former more intense parasite circulation among NHPs due to their proximity to humans at a higher populational density. The presence ofPlasmodiumpositive NHPs in the surveyed areas, being therefore potential parasite reservoirs, needs to be considered in any malaria surveillance program.
Palavras-chave
malaria, Plasmodium malariae, MSP1, non-human primates, serology, Brazil
URI
https://observatorio.fm.usp.br/handle/OPI/38095
Referências
  1. Alvarenga DAM, 2017, MALARIA J, V16, DOI 10.1186/s12936-017-1724-0
  2. Araujo MS, 2013, MALARIA J, V12, DOI 10.1186/1475-2875-12-180
  3. Birkenmeyer L, 2010, AM J TROP MED HYG, V82, P996, DOI 10.4269/ajtmh.2010.09-0022
  4. Brasil P, 2017, LANCET GLOB HEALTH, V5, pE1038, DOI 10.1016/S2214-109X(17)30333-9
  5. Bueno MG, 2013, ECOHEALTH, V10, P48, DOI 10.1007/s10393-012-0809-z
  6. Bueno MG, 2017, INT J PRIMATOL, V38, P1017, DOI 10.1007/s10764-017-9994-5
  7. Buery JC, 2017, MALARIA J, V16, DOI 10.1186/s12936-017-2080-9
  8. Costa DC, 2014, MEM I OSWALDO CRUZ, V109, P641, DOI 10.1590/0074-0276130578
  9. da FONSECA FLAVIO, 1951, MEM INST OSWALDO CRUZ, V49, P543, DOI 10.1590/S0074-02761951000100008
  10. de Duarte AMR, 2006, J MED PRIMATOL, V35, P87, DOI 10.1111/j.1600-0684.2006.00148.x
  11. DEANE LM, 1992, MEM I OSWALDO CRUZ, V87, P1, DOI 10.1590/S0074-02761992000700001
  12. Drakeley CJ, 2005, P NATL ACAD SCI USA, V102, P5108, DOI 10.1073/pnas.0408725102
  13. Elizardez YB, 2019, PLOS ONE, V14, DOI 10.1371/journal.pone.0219629
  14. Fernandez-Becerra C, 2010, MALARIA J, V9, DOI 10.1186/1475-2875-9-29
  15. Gomez A, 2008, ANN NY ACAD SCI, V1149, P16, DOI 10.1196/annals.1428.046
  16. Gonder Richard, 1908, Malaria Leipzig, V1
  17. Guimaraes LO, 2012, ACTA TROP, V124, P27, DOI 10.1016/j.actatropica.2012.05.016
  18. Guimaraes LO, 2015, BMC INFECT DIS, V15, DOI 10.1186/s12879-015-1238-8
  19. Healer J, 2018, PARASITOLOGY, V145, P839, DOI [10.1017/S0031182017001949, 10.1017/s0031182017001949]
  20. Holder AA, 2009, PARASITOLOGY, V136, P1445, DOI 10.1017/S0031182009990515
  21. HOLDER AA, 1982, J EXP MED, V156, P1528, DOI 10.1084/jem.156.5.1528
  22. Kock RA, 2010, REV SCI TECH OIE, V29, P329, DOI 10.20506/rst.29.2.1980
  23. de Alvarenga DAM, 2015, MALARIA J, V14, DOI 10.1186/s12936-015-0606-6
  24. Mittermeier R.A., 1988, P145
  25. Mittermeier R.A., 2007, MONKEYS ATLANTIC FOR, V3
  26. de Assis GMP, 2016, MEM I OSWALDO CRUZ, V111, P570, DOI 10.1590/0074-02760160222
  27. Figueiredo MAP, 2015, REV BRAS PARASITOL V, V24, P122, DOI 10.1590/S1984-29612015034
  28. Polley SD, 2003, INFECT IMMUN, V71, P1833, DOI 10.1128/IAI.71.4.1833-1842.2003
  29. Priest JW, 2018, MALARIA J, V17, DOI 10.1186/s12936-018-2566-0
  30. Duarte AMRD, 2008, ACTA TROP, V107, P179, DOI 10.1016/j.actatropica.2008.05.020
  31. de Abreu FVS, 2019, PLOS NEGLECT TROP D, V13, DOI 10.1371/journal.pntd.0007906
  32. Silva TRM, 2019, ZOONOSES PUBLIC HLTH, V66, P798, DOI 10.1111/zph.12626
  33. Soares IS, 1997, INFECT IMMUN, V65, P1606, DOI 10.1128/IAI.65.5.1606-1614.1997
  34. Stewart L, 2009, PLOS ONE, V4, DOI 10.1371/journal.pone.0006083
  35. Yamasaki T, 2011, J MED PRIMATOL, V40, P392, DOI 10.1111/j.1600-0684.2011.00498.x

Coleções
Artigos e Materiais de Revistas Científicas - LIM/49
Artigos e Materiais de Revistas Científicas - ODS/03